1.
Chemistry
; 25(17): 4491-4495, 2019 Mar 21.
Article
in English
| MEDLINE
| ID: mdl-30793810
ABSTRACT
The reductive Barbier coupling of aromatic halides and electrophiles has been achieved using a CoBr2 /1,10-phenanthroline catalytic system and over stoichiometric amounts of zinc. The reaction displayed a broad scope of substrates, including (hetero)aryl chlorides as pro-nucleophiles and aldehydes or imines as electrophiles, leading to diarylmethanols and diarylmethylamines in moderate to excellent yields, respectively.