ABSTRACT
Um número crescente de cepas de Staphylococcus aureus meticilina resistente (MRSA) apresentam resistência a múltiplos agentes antimicrobianos e são implicadas como causas de infecções hospitalares. S.aureus podem ser isolados de ambiente hospitalar e profissionais da saúde, revelando o risco de transmissão desses microrganismos pelo contato direto ou indireto com pacientes hospitalizados. Objetivou-se nesta revisão correlacionar este microrganismo com infecções hospitalares e avaliar as possíveis fontes de infecção, bem como enfatizar a importância do investimento em ações de educação em saúde que culminem em minimização de infecções hospitalares.
A growing number of methicillin-resistant Staphylococcusaureus strains in the hospital are acquiring multidrug resistance and S. aureus is the most commonly isolated pathogen in hospital infections. Since viable S. aureus can be isolated from hospital staff, there is a real risk of their transmission by direct or indirect contact with hospital patients. The aim of this review was to correlate these microorganisms with hospital infections and assess the possible sources of infection, with an emphasis one ducational measures as the most important factor in reducing nosocomial infection rates.
Subject(s)
Cross Infection , Methicillin Resistance , Staphylococcal Infections , Staphylococcus aureusABSTRACT
Endophytic microorganisms are relatively unstudied as potential sources of novel natural products for medical and commercial exploitation. The aim of this work was to investigate some Brazilian tropical savannah trees Cassia leptophylla and Prunus spp. in order to isolate the endophytic microorganisms associated with these plants. The samples were disinfected to eliminate the epiphytic population. Colonies were diluted and displayed as drops in media and growing colonies were inactivated. Staphylococcus coagulase-positive strain was used as indicator microorganism and subjected to the antibioses test. Data showed that the microorganisms isolated from Cassia leptophylla had no inhibition against Staphylococcus. On the other hand, microorganisms isolated from Prunus spp. leaves showed antibacterial activity and inhibited Staphylococcus when cultivated in peptone agar as well as in yeast extract agar. Investigation proceeds in order to classify the isolated microorganisms presenting bioactive substance and exploit the potential of the compounds produced to inhibit the indicator bacteria. Other bioactive properties will be investigated.