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1.
World Neurosurg ; 182: 58, 2024 Feb.
Article in English | MEDLINE | ID: mdl-37979683

ABSTRACT

Aneurysms at the superior cerebellar artery (SCA) are commonly treated endovascularly because of their location around the basilar artery,1,2 but they are not intimately related with thalamoperforators. Therefore in younger patients, those with wide-necked aneurysms, or those with multiple ipsilateral aneurysms, surgery remains a treatment option.3 We present a 52-year-old woman with dizziness in whom multiple, unruptured intracranial aneurysms were identified. Imaging demonstrated a 9-mm right-sided SCA aneurysm and 5-mm right and mirror 3-mm left M1 segment middle cerebral artery aneurysms. The patient gave consent to undergo surgery after counseling regarding her treatment options. A pterional and temporal craniotomy was performed to allow for half-and-half subtemporal and transsylvian approaches (Video 1). Here, we discuss the nuances of the approach related to the anatomy of SCA aneurysms. The challenges of the surgery can be mediated with techniques including division of the tentorium for enhanced exposure and early proximal control with temporary clinping or the use of adenosine (cardiac arrest). Our patient remained neurologically stable postoperatively and in 1-year follow-up. SCA aneurysms are easily visualized by the subtemporal and transsylvian approaches; they are frequently located adjacent to the posterior cerebral artery above and the SCA below. A modified transcavernous approach using the orbitozygomatic craniotomy has been described for access to basilar tip aneurysms.4 While comparable, this case demonstrates the efficient workflow to clip multiple aneurysms using a single, combined approach. In patients with multiple aneurysms presenting ipsilaterally or with comorbid conditions that complicate endovascular embolization, surgery should be considered as a definitive and safe treatment strategy. The patient consented to publication.


Subject(s)
Intracranial Aneurysm , Middle Cerebral Artery , Humans , Female , Middle Aged , Middle Cerebral Artery/surgery , Intracranial Aneurysm/complications , Intracranial Aneurysm/diagnostic imaging , Intracranial Aneurysm/surgery , Basilar Artery/diagnostic imaging , Basilar Artery/surgery , Posterior Cerebral Artery/surgery , Craniotomy/methods
2.
Acta Neurochir (Wien) ; 165(12): 3793-3798, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37779179

ABSTRACT

BACKGROUND: Dural arteriovenous fistulas (dAVFs) at the superior petrosal sinus are a rare but important subtype that pose a high risk of mortality and morbidity. Treatment for these lesions can be challenging with stand-alone endovascular methods. METHODS: We describe our "in-out-in" technique for disconnecting dAVFs at the superior petrosal sinus, which includes definitive sacrifice of the superior petrosal sinus and the transverse sigmoid sinus, if involved. This method achieves complete fistula obliteration and minimizes recurrence risk with new arterial feeders. CONCLUSIONS: The in-out-in technique is a safe and effective approach for the treatment of dAVFs involving the superior petrosal sinus.


Subject(s)
Central Nervous System Vascular Malformations , Embolization, Therapeutic , Endovascular Procedures , Transverse Sinuses , Humans , Cranial Sinuses/diagnostic imaging , Cranial Sinuses/surgery , Central Nervous System Vascular Malformations/diagnostic imaging , Central Nervous System Vascular Malformations/surgery , Embolization, Therapeutic/methods , Endovascular Procedures/methods
3.
Cancers (Basel) ; 15(11)2023 May 24.
Article in English | MEDLINE | ID: mdl-37296858

ABSTRACT

The sellar and parasellar region can be affected by diverse pathologies. The deep-seated location and surrounding critical neurovascular structures make treatment challenging; there is no singular, optimal approach for management. The history and development of transcranial and transsphenoidal approaches by pioneers in skull base surgery were largely aimed at treating pituitary adenomas, which are the most common lesions of the sella. This review explores the history of sellar surgery, the most commonly used approaches today, and future considerations for surgery of the sellar/parasellar region.

4.
Acta Neurochir (Wien) ; 165(12): 3737-3741, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37256439

ABSTRACT

BACKGROUND: Posterior inferior cerebellar artery (PICA) aneurysms are uncommon, and their management is challenging because of the complex angioarchitecture of the PICA and the frequently nonsaccular aneurysm presentation. Endovascular therapy may not be feasible. METHODS: We describe our technique of clip trapping with occipital artery (OA)-to-PICA bypass to treat a PICA aneurysm. Because the aneurysm affected the ipsilateral, dominant PICA, an OA-PICA bypass was chosen to ensure adequate flow and reduce risk to the contralateral PICA supply. CONCLUSION: The OA-PICA anastomosis is a safe and effective method to successfully achieve flow preservation with bypass reconstruction and aneurysm trapping.


Subject(s)
Cerebral Revascularization , Intracranial Aneurysm , Vertebral Artery Dissection , Humans , Cerebral Revascularization/methods , Cerebellum/surgery , Vertebral Artery/surgery , Vertebral Artery Dissection/surgery , Intracranial Aneurysm/diagnostic imaging , Intracranial Aneurysm/surgery
5.
Neurosurg Clin N Am ; 34(3): 417-423, 2023 Jul.
Article in English | MEDLINE | ID: mdl-37210130

ABSTRACT

Meningiomas are the most common intracranial brain tumor. Spheno-orbital meningiomas are a rare subtype that originate at the sphenoid wing and characteristically extend to the orbit and surrounding neurovascular structures via bony hyperostosis and soft tissue invasion. This review summarizes early characterizations of spheno-orbital meningiomas, presently understood tumor characteristics, and current management strategies.


Subject(s)
Brain Neoplasms , Meningeal Neoplasms , Meningioma , Humans , Meningioma/surgery , Treatment Outcome , Sphenoid Bone/surgery , Neoplasm Recurrence, Local/pathology , Brain Neoplasms/pathology , Meningeal Neoplasms/surgery
6.
Int J Mol Sci ; 24(6)2023 Mar 21.
Article in English | MEDLINE | ID: mdl-36982990

ABSTRACT

Inflammatory disease of the pituitary gland is known as hypophysitis. There are multiple histological subtypes, the most common being lymphocytic, and the pathogenesis is variable and diverse. Hypophysitis can be primary and idiopathic or autoimmune related, or secondary to local lesions, systemic disease, medications, and more. Although hypophysitis was previously accepted as an exceedingly rare diagnosis, a greater understanding of the disease process and new insights into possible etiologic sources have contributed to an increased frequency of recognition. This review provides an overview of hypophysitis, its causes, and detection strategies and management.


Subject(s)
Hypophysitis , Humans , Hypophysitis/diagnosis , Hypophysitis/etiology , Pituitary Gland , Lymphocytes/pathology
7.
World Neurosurg ; 172: 71, 2023 Apr.
Article in English | MEDLINE | ID: mdl-36739899

ABSTRACT

Tumors of the optic pathway and/or hypothalamus are uncommon, and the majority occur in patients with neurofibromatosis type 1.1,2 These lesions can be managed with a "watch-and-wait" approach; however, when treatment is indicated, the optimal strategy is wholly case dependent. We present a 22-year-old female patient with neurofibromatosis type 1 who had a partially cystic mass within the right mamillary body (Video 1). The mass was present on prior imaging but had increased in size and was newly enhancing with evidence of mass effect on the right optic tract. Given her history and the lesion's progression, treatment was recommended. The patient elected for surgery over radiation. Preoperatively, there were no visual field deficits or signs of hypopituitarism. We undertook a unilateral, extended transsphenoidal approach. Additional bony removal of the tuberculum sellae and planum sphenoidale enabled greater exposure of the anterior cranial fossa. The circular sinus was cauterized and divided for visualization of the pituitary stalk and clear identification of the hypothalamus. This provided an operative corridor superior to the pituitary gland and just beneath the optic nerves. The procedure proceeded without complication, and gross total resection was achieved. Postoperative imaging demonstrated gross total resection with a normal-appearing pituitary gland. Of note, the patient did experience mildly elevated postoperative sodium and was treated with desmopressin for transient diabetes insipidus. Twelve- and 24-month follow-up imaging showed no recurrence. The extended transsphenoidal approach used here offers a safe and suitable working corridor to achieve total resection of hypothalamic lesions without injury to the pituitary gland.


Subject(s)
Hypothalamic Neoplasms , Meningeal Neoplasms , Neurofibromatosis 1 , Adult , Female , Humans , Young Adult , Hypothalamic Neoplasms/surgery , Meningeal Neoplasms/surgery , Pituitary Neoplasms/diagnostic imaging , Pituitary Neoplasms/surgery , Pituitary Neoplasms/pathology , Retrospective Studies , Sella Turcica/surgery , Treatment Outcome
8.
J Rare Dis Orphan Drugs ; 3: 11-26, 2022 Jun 07.
Article in English | MEDLINE | ID: mdl-36221287

ABSTRACT

Dural Arteriovenous Fistulas (AVF) represent about 10% of all intracranial vascular lesions. Although they seem benign in nature, the presence of retrograde venous makes them aggressive, with a high risk of complications. Patients may be clinically asymptomatic or experience symptoms ranging from mild to severe hemorrhage, depending on their location. Different treatments are available, but recently, the development of catheter intervention allows most patients to be cured with transcatheter embolization. Stereotactic radiosurgery achieves excellent rates of obliteration for low-grade lesions. In this review, we try to highlight the recent advances in the management of dural AVF.

9.
Biomedicines ; 11(1)2022 Dec 20.
Article in English | MEDLINE | ID: mdl-36672510

ABSTRACT

Pediatric stroke is an important cause of mortality and morbidity in children. There is a paucity of clinical trials pertaining to pediatric stroke management, and solidified universal guidelines are not established for children the way they are for the adult population. Diagnosis of pediatric stroke can be challenging, and it is often delayed or mischaracterized, which can result in worse outcomes. Understanding risks and appropriate therapy is paramount to improving care.

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