Subject(s)
Dermatitis, Occupational/etiology , Food Handling , Seafood/adverse effects , Urticaria/etiology , Adult , Female , Humans , MaleABSTRACT
Anetoderma is a rare elastolytic disorder included within the group of cutaneous atrophies. Its pathogenesis is not yet clearly established, but immunological mechanisms could play an important role in dermal elastolysis. It has been associated with different autoantibodies and autoimmune disorders. We present a case of anetoderma in a systemic lupus erythematosus patient with anti-proliferating-cell-nuclear-antigen and antiphospholipid antibodies, highlighting the peculiarities of such an association.
Subject(s)
Lupus Erythematosus, Systemic/complications , Skin Diseases/complications , Adult , Antibodies, Antinuclear/blood , Antibodies, Antiphospholipid/blood , Elastic Tissue/pathology , Humans , Lupus Erythematosus, Systemic/immunology , Lupus Erythematosus, Systemic/pathology , Male , Proliferating Cell Nuclear Antigen/immunology , Skin Diseases/immunology , Skin Diseases/pathologyABSTRACT
Presentamos el caso de dos hermanos con distrofia de las veinte uñas (DVU). Se describen los aspectos clínicos, histopatológicos y etiopatogénicos de esta rara entidad. Destacamos la escasa frecuencia con la que en la literatura dermatológica aparecen descritos casos de DVU de presentación familiar (AU)
Subject(s)
Humans , Male , Child , Nails, Malformed/genetics , Nail Diseases/genetics , AtrophyABSTRACT
We present further evidence that granuloma annulare and autoimmune thyroiditis may be associated. Only 11 cases have been previously reported with this association as far as we know. It may be advantageous to consider checking the thyroid-stimulating hormone and/or antithyroid antibodies before administering medications that could affect thyroid function in patients with granuloma annulare.