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Arkh Patol ; 54(8): 24-7, 1992.
Article in Russian | MEDLINE | ID: mdl-1482304

ABSTRACT

Cell composition of the parathyroid gland was studied under normal conditions, after the hypo- or hyperloading with calcium gluconate and at hyperfunction. Three types of parathyrocytes were established that probably reflect different stages of their life cycle: the first--poorly differentiated cell, the second--mature differentiated cell and the third--degenerated cell. The majority of cells were represented by the parathyrocytes of the 2nd type the varieties of which reflect a non-active (A-subtype) and active (B-subtype) phases of secretion. The number of A-cells is increased under the condition of the hyposecretion and the relative number of B-cells under the condition of experimental hypersecretion.


Subject(s)
Calcium/metabolism , Parathyroid Glands/pathology , Animals , Calcium Gluconate/pharmacology , Cell Differentiation/drug effects , Homeostasis/drug effects , Homeostasis/physiology , Parathyroid Glands/drug effects , Parathyroid Glands/metabolism , Rats
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