ABSTRACT
The results of clinico-morfological investigation of 220 arteries of the brain base from dead patients with aneurisms are in the article. The new facts and terms such as bifurcational hemodynamic aneurisms, segmental arterial ring of the brain and aneurysmal disease of the brain have been introduced. We have showed that aneurisms forms in the area of bifurcation, but not in linear segments of vessels. A junction of arteries in the bifurcation of vessels, formed by connective tissue, units muscle segments and takes place in development of aneurisms. The term of "aneurism" as a saccular evagination of all layers of arterial wall was prejudiced. A term as "diverticulum" could be use for denomination of evagination. Two types of aneurysmal disease of the brain clinical course have been separated out. The fist one is dysembryoplastic type with connective tissue deficiency and the second one--involutional hypertensive type at patients with long-term arterial hypertension.
Subject(s)
Cerebral Arteries/pathology , Cerebral Arteries/physiopathology , Intracranial Aneurysm/classification , Intracranial Aneurysm/pathology , Intracranial Aneurysm/physiopathology , HumansSubject(s)
Brain Neoplasms/diagnosis , Brain Neoplasms/therapy , Germinoma/diagnosis , Germinoma/therapy , Adolescent , Animals , Biomarkers, Tumor/analysis , Brain Neoplasms/pathology , Chemotherapy, Adjuvant , Cranial Irradiation , Germinoma/pathology , Humans , Magnetic Resonance Imaging , Male , Prognosis , Radiotherapy Dosage , Radiotherapy, AdjuvantABSTRACT
One hundred and twenty patients who died in 2003 to 2008 were examined; of them 27 patients died from ruptured aneurysm of the cerebral arterial ring (CAR). Vascular anthropometry and morphometry were made. Correlation analysis revealed a close direct correlation between the perimeters of elastic vessels (the aorta) and those of vessels of muscular type (the major arteries of the basis cerebri) and a close inverse correlation between the perimeters of the above arteries and human height. On the basis of these data, the authors identified three constitutional types of CAR: hypoplastic, normoplastic, and hyperplastic. The distribution by age and height (somatotype) in the variational series made up of those who had died from ruptured aneurysm was found to be bimodal. The clinical and morphological comparisons of the course of aneurysmal disease in these subgroups can identify two constitutional risk groups for development of aneurysmal disease: dysplastic and involutionally hypertensive.
