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Bull Exp Biol Med ; 135(5): 495-8, 2003 May.
Article in English | MEDLINE | ID: mdl-12910293

ABSTRACT

We studied the retinoprotective effect of Epithalon administered to the offspring of Campbell rats during postnatal ontogeny and to mothers before mating and during pregnancy. After this treatment the morphological structure and functional activity of the retina were preserved for a longer period compared to control rats (by 2 times) and to the animals receiving the peptide only during postnatal ontogeny (by 30%).


Subject(s)
Eye Diseases, Hereditary/drug therapy , Eye Diseases, Hereditary/pathology , Oligopeptides/therapeutic use , Pigment Epithelium of Eye/pathology , Retinal Degeneration/drug therapy , Retinal Degeneration/pathology , Age Factors , Animals , Animals, Newborn , Atrophy , Female , Humans , Pigment Epithelium of Eye/anatomy & histology , Pigment Epithelium of Eye/metabolism , Pregnancy , Rats
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