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J Perinatol ; 43(8): 982-990, 2023 08.
Article in English | MEDLINE | ID: mdl-37188774

ABSTRACT

OBJECTIVE: To provide the best clinical practice guidance for surfactant use in preterm neonates with respiratory distress syndrome (RDS). The RDS-Neonatal Expert Taskforce (RDS-NExT) initiative was intended to add to existing evidence and clinical guidelines, where evidence is lacking, with input from an expert panel. STUDY DESIGN: An expert panel of healthcare providers specializing in neonatal intensive care was convened and administered a survey questionnaire, followed by 3 virtual workshops. A modified Delphi method was used to obtain consensus around topics in surfactant use in neonatal RDS. RESULT: Statements focused on establishing RDS diagnosis and indicators for surfactant administration, surfactant administration methods and techniques, and other considerations. After discussion and voting, consensus was achieved on 20 statements. CONCLUSION: These consensus statements provide practical guidance for surfactant administration in preterm neonates with RDS, with a goal to contribute to improving the care of neonates and providing a stimulus for further investigation to bridge existing knowledge gaps.


Subject(s)
Pulmonary Surfactants , Respiratory Distress Syndrome, Newborn , Infant, Newborn , Humans , Infant, Premature , Surface-Active Agents/therapeutic use , Respiratory Distress Syndrome, Newborn/drug therapy , Pulmonary Surfactants/therapeutic use , Intensive Care, Neonatal
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