1.
J Pharm Sci
; 66(2): 263-4, 1977 Feb.
Article
in English
| MEDLINE
| ID: mdl-839425
ABSTRACT
Several derivatives of 2-indolyl 5-(1,2,3,6-tetrahydropyridyl) ketone with various substituents on the pyridine nitrogen and with or without a benzenesulfonyl group on the indole nitrogen were synthesized and characterized by spectroscopic and analytical data. Only one showed erratic but confirmed activity in the P-388 screen. The other derivatives were inactive in the L-1210 leukemia screen.
Subject(s)
Antineoplastic Agents/chemical synthesis , Indoles/chemical synthesis , Alkylation , Animals , Antineoplastic Agents/therapeutic use , Cell Survival/drug effects , Cells, Cultured , Indoles/pharmacology , Leukemia L1210/drug therapy , Leukemia, Experimental/drug therapy , Mice , Oxidation-Reduction , Pyridines/chemical synthesis , Pyridines/pharmacology
2.
Thromb Res
; 4(2): 261-9, 1974 Feb.
Article
in English
| MEDLINE
| ID: mdl-4831004
3.
Tetrahedron Lett
; (7): 507-8, 1970 Feb.
Article
in English
| MEDLINE
| ID: mdl-5417088
