Presence of risk factors for thyroid cancer does not improve the performance of ultrasound screening for thyroid nodules in patients with obesity.

PURPOSE: It has been suggested, on a theoretical basis, that ultrasound screening of thyroid nodules in obese patients with additional risk factors (family history, chronic autoimmune thyroiditis or high thyrotropin) might be cost-effective for the early detection and treatment of thyroid cancer. The present study evaluates if this approach can be validated in a real clinical setting. METHODS: Patients with obesity who attended hospital-based clinics were evaluated for risk factors of thyroid cancer and ultrasound screened for thyroid nodularity. Detected nodules were evaluated according to current guidelines. RESULTS: A total of 429 patients were evaluated (70.2% women, mean age 49.1 ± 11.0, mean body mass index 42.6 ± 5.8 kg/m2 ). Risk factors were present in 129 (30.1%) patients. Thyroid nodules with indication for fine-needle aspiration biopsy were detected in 69 (16.1%). We did not find differences in the risk of harbouring thyroid nodules according to the presence of risk factors (no risk factors 16.6%, risk factors 14.1%, P = .64). No single risk factor conferred an increased risk for thyroid nodules During the screening procedure, four cases of thyroid cancer were detected, none of them with the evaluated risk factors. CONCLUSION: The presence of known risk factors for thyroid cancer does not improve the performance of a US screening strategy aimed at the detection of thyroid nodules in obese patients. According to current guidelines, screening for thyroid nodules in obese patients is not recommended regardless of the presence of thyroid cancer risk factors.

Use of communication technologies by people with type 1 diabetes in the social networking era. A chance for improvement.

AIMS: To evaluate the health-related use of Web 2.0 tools by patients with type 1 diabetes. METHODS: Cross-sectional survey assessing views and usage of the Internet, Apps and Web 2.0. RESULTS: Number of participants: 289 (age 42.8±13.5 years; diabetes duration 18.4±12.2 years; 58.7% males; 39% with an upper secondary or higher education level). Web 2.0 usage for health purposes was low with 19.6% and 14% of Web 2.0 members (147; 50.9%) having health-related contacts and posting health comments. Health-related Apps were used by 35.4% of Smartphone owners (161; 55.7%). 75.3% patients would share information online with professionals, preferably through e-mail (78.7%) rather than Facebook (47.7%). 141 (66.5%) of those willing to share information would participate in a professional-moderated Facebook group. CONCLUSIONS: Web 2.0 and Apps usage for health purposes is low. The difference between the use of Web 2.0 networks and the willingness to participate in professional-moderated Web 2.0 groups points to the need of a higher implication of health professionals in promoting Web 2.0 technologies if these are to be adopted in a clinical setting. Currently, e-mail is the tool to be considered when aiming to increase online communication with patients with type 1 diabetes.

Aspectos epidemiológicos y carga asistencial de gastroenteritis agudas por Campylobacter y Salmonella / Campylobacter and Salmonella acute gastroenteritis: Epidemiology and health care utilization

Fundamento y objetivo: En Cataluña, los sistemas de notificación y vigilancia no permiten conocer la incidencia real ni la carga asistencial de las gastroenteritis agudas (GEA) bacterianas de origen alimentario por Campylobacter ySalmonella, objeto de este estudio. Pacientes y métodos: Estudio descriptivo de los casos de GEA por Campylobacter y Salmonella en los años 2002 y 2012 en una región de Cataluña, España, identificados a partir de cultivos microbiológicos. Resultados: La incidencia estimada de GEA por Salmonella se redujo un 50% en 2012, y la de Campylobacter, un 20%. Los niños entre 1-4 años fueron los más afectados en ambos períodos. Se observaron diferencias significativas según el microorganismo en la presentación clínica de algunos síntomas y en la duración de la enfermedad. Acudieron al Servicio de Urgencias el 63,7% de los casos, y un 15% requirieron hospitalización, siendo más frecuente entre los casos de salmonelosis. Conclusión: La incidencia de GEA por Campylobacter y Salmonella se ha reducido, pero continúa siendo importante, como lo es la carga asistencial para ambas infecciones. El control de estas dolencias requiere una mayor adecuación de los actuales sistemas de vigilancia epidemiológica (AU)

Background and objective: In Catalonia the current surveillance systems do not allow to know the true incidence or the health care utilization of acute gastroenteritis (AGE) caused by Campylobacter and Salmonella infections. The aim of this study is to analyze these characteristics. Patients and methods: Descriptive study of Campylobacter and Salmonella infections reported in 2002 and 2012 in Catalonia, Spain. We included cases isolated and reported by the laboratory to a regional Surveillance Unit. Results: The estimated incidence of Salmonella and Campylobacter AGE decreased by almost 50% and 20% respectively in 2012. Children between one and 4 years old were the most affected in both years. Significant differences in the clinical characteristics and disease duration were observed betweenCampylobacter and Salmonella. Visits to the Emergency Department and hospitalization rates were 63.7% and 15%, being more frequent among salmonellosis cases. Conclusion The estimated incidence of Campylobacter and Salmonella infections has decreased, however rates are still important, as well as it is the health care utilization in both diseases. Current surveillance systems need appropriateness improvements to reach a better control of these infections (AU)

[Campylobacter and Salmonella acute gastroenteritis: epidemiology and health care utilization]. / Aspectos epidemiológicos y carga asistencial de gastroenteritis agudas por Campylobacter y Salmonella.

BACKGROUND AND OBJECTIVE: In Catalonia the current surveillance systems do not allow to know the true incidence or the health care utilization of acute gastroenteritis (AGE) caused by Campylobacter and Salmonella infections. The aim of this study is to analyze these characteristics. PATIENTS AND METHODS: Descriptive study of Campylobacter and Salmonella infections reported in 2002 and 2012 in Catalonia, Spain. We included cases isolated and reported by the laboratory to a regional Surveillance Unit. RESULTS: The estimated incidence of Salmonella and Campylobacter AGE decreased by almost 50% and 20% respectively in 2012. Children between one and 4 years old were the most affected in both years. Significant differences in the clinical characteristics and disease duration were observed between Campylobacter and Salmonella. Visits to the Emergency Department and hospitalization rates were 63.7% and 15%, being more frequent among salmonellosis cases. CONCLUSION: The estimated incidence of Campylobacter and Salmonella infections has decreased, however rates are still important, as well as it is the health care utilization in both diseases. Current surveillance systems need appropriateness improvements to reach a better control of these infections.

Pertussis epidemic despite high levels of vaccination coverage with acellular pertussis vaccine

INTRODUCTION: We describe the pertussis epidemic, based only on confirmed whooping cough cases. We have analyzed data on the diagnosis, epidemiology and vaccine history in order to understand the factors that might explain the trends of the disease. METHODS: A descriptive study of the confirmed pertussis cases reported during 2011 in the Vallès region (population 1,283,000). Laboratory criteria for confirmed pertussis cases include isolation of Bordetella pertussis from a clinical specimen or detection of B. pertussis by PCR in nasopharyngeal swabs. RESULTS: A total of 421 pertussis confirmed cases were reported, which was the highest incidence reported in the last decade (33 cases/100,000 people/year in 2011). The highest incidence rate was among infants less than 1 year old (448/100,000), followed by children 5-9 years old (154/100,000). Pertussis cases aged 2 months-1 year were 90% vaccinated following the current DTaP schedule for their age group in Catalonia, and cases of 5-9 years were 87% fully vaccinated with 5 doses of DTaP vaccine. There were no deaths, although 8% of cases were hospitalized. Pertussis was more severe in infants, 30% required hospitalization despite having received the vaccine doses corresponding to their age. Children of 5-9 years were most often identified as primary cases in households or school clusters. CONCLUSIÓN: Despite high levels of vaccination coverage, pertussis circulation cannot be controlled at all. The results question the efficacy of the present immunization programmes

INTRODUCCIÓN: Se describe la epidemia de tos ferina en el año 2011 solo en casos confirmados. Se analizan datos sobre diagnóstico, epidemiología y antecedentes vacunales que podrían explicar las tendencias de la enfermedad. MÉTODOS: Estudio descriptivo de los casos confirmados de tos ferina notificados durante 2011 en la región del Vallès (población 1.283.000 habitantes). Los criterios de laboratorio para confirmación de un caso incluyen el aislamiento de Bordetella pertussis mediante cultivo en una muestra clínica o detección deB. pertussis por PCR en muestras nasofaríngeas. RESULTADOS: Fueron declarados 421 casos confirmados, siendo la incidencia más alta de los últimos 10 años (33 casos por 100.000 personas/año en 2011). La mayor tasa de incidencia fue en niños < 1 año de edad (448/100.000), seguido de los de 5-9 años (154/100.000). Los casos entre 2 meses y 1 año de edad estaban el 90% vacunados con DTaP según el calendario vacunal vigente en Cataluña para esta edad, entre 5-9 años el 87% estaban completamente vacunados con 5 dosis de DTaP. No hubo defunciones, pero el 8% de los casos fueron hospitalizados. La enfermedad fue más grave en < 1 año, y el 30% fueron hospitalizados a pesar de estar bien vacunados para su edad. Los casos de 5-9 años fueron más frecuentemente identificados como casos primarios en los hogares o grupos escolares. CONCLUSIÓN: A pesar de los altos niveles de cobertura vacunal, la circulación de la tos ferina no se puede controlar del todo. Los resultados ponen en duda la eficacia de los programas de inmunización actuales

Does health education affect BMI? Evidence from a school-based randomised-control trial.

We examine the effects of a comprehensive school-based health education programme (introducing healthy habits in the curriculum) to combat childhood obesity in the mid-size urban city of Granollers (Catalonia, Spain). The intervention was carried out between 2006 and 2008. New anthropometric measurements were obtained in 2008, 2010 and 2012. The length of the intervention evaluation constitutes a valuable contribution to the existing literature. Data refers to 509 schoolchildren aged 6 years old from 16 schools that were randomly assigned to either the intervention group or to the control group. Our results indicate that children's BMI in the treatment group was reduced by 1.13 kg/m(2) four years after the intervention, representing on average and for an average height, a loss of 1.6 kg. We examine heterogeneity and find that most effect is driven by children coming from disadvantaged backgrounds whilst no differences were obtained differentiating by gender.

Pertussis epidemic despite high levels of vaccination coverage with acellular pertussis vaccine.

INTRODUCTION: We describe the pertussis epidemic, based only on confirmed whooping cough cases. We have analyzed data on the diagnosis, epidemiology and vaccine history in order to understand the factors that might explain the trends of the disease. METHODS: A descriptive study of the confirmed pertussis cases reported during 2011 in the Vallès region (population 1,283,000). Laboratory criteria for confirmed pertussis cases include isolation of Bordetella pertussis from a clinical specimen or detection of B. pertussis by PCR in nasopharyngeal swabs. RESULTS: A total of 421 pertussis confirmed cases were reported, which was the highest incidence reported in the last decade (33 cases/100,000 people/year in 2011). The highest incidence rate was among infants less than 1 year old (448/100,000), followed by children 5-9 years old (154/100,000). Pertussis cases aged 2 months-1 year were 90% vaccinated following the current DTaP schedule for their age group in Catalonia, and cases of 5-9 years were 87% fully vaccinated with 5 doses of DTaP vaccine. There were no deaths, although 8% of cases were hospitalized. Pertussis was more severe in infants, 30% required hospitalization despite having received the vaccine doses corresponding to their age. Children of 5-9 years were most often identified as primary cases in households or school clusters. CONCLUSION: Despite high levels of vaccination coverage, pertussis circulation cannot be controlled at all. The results question the efficacy of the present immunization programmes.

Evaluación a medio plazo de una intervención educativa en hábitos alimentarios y de actividad física en escolares: estudio Avall 2 / Medium-term evaluation of an educational intervention on dietary and physical exercise habits in schoolchildren: The Avall 2 study

Objetivo Determinar si los beneficios observados en alimentación, actividad física e índice de masa corporal se mantenían a los 2 años de haber finalizado la intervención educativa. Material y método Estudio longitudinal experimental de 4 años de duración, aleatorizado por conglomerados, para evaluar un programa de intervención dirigido a escolares de primer curso de educación primaria de las escuelas de Granollers. La intervención consistió en promover hábitos alimentarios saludables y potenciar la actividad física mediante la pedagogía educativa Investigación, Visión, Acción y Cambio (IVAC) aplicada a lo largo de 2 cursos escolares (2006-2008). Se determinó in situ el peso y la talla de cada niño, y las familias autocompletaron una encuesta de actividad física y alimentación en el 2006, 2008 y 2010.ResultadosEn el 2010 se observó un mayor incremento del índice de masa corporal de los escolares del grupo control (2,84±0,22 vs 1,96±0,163 kg/m2, p<0,001). La prevalencia de escolares con sobrepeso y obesidad aumentó respectivamente en un 8 y un 0,5% en el grupo control, mientras que en el grupo intervención se incrementó la prevalencia de sobrepeso (5,3%) y se redujo la de obesidad (3,6%). La prevalencia de escolares con exceso de peso aumentó en un 8,5% en el grupo control y en un 1,8% en el de intervención. A los 2 años de finalizar la intervención educativa se mantuvo la reducción del incremento del índice de masa corporal, independientemente del sexo, la procedencia, la obesidad materna y el nivel de estudios de los progenitores. Conclusiones La intervención educativa mediante el empleo del método pedagógico IVAC ayuda a contener el actual incremento de obesidad infantil (AU)

Objective To assess whether the benefits seen in nutrition, physical activity and body mass index were maintained at 2 years of completion of the educational intervention. Material and methods An experimental, longitudinal, 4-year, two-arm, parallel study with cluster randomization to assess an intervention program aimed at children in their first year of primary schooling attending schools in the city of Granollers. Intervention consisted of promoting healthy dietary habits and increasing physical activity through the educational pedagogy Investigation, Vision, Action and Change (IVAC), applied over 2 school years (2006-2008). Weight and height of each child were measured in situ, and families self-completed a physical activity survey and the Krece Plus quick test in 2006, 2008, and 2010.ResultsA greater increase in body mass index was seen in 2010 in children from the control group (2.84±0.22 vs 1.96±0.163kg/m2, <0.001). Prevalence of overweight and obesity increased by 8% and 0.5%, respectively in schoolchildren in the control group, while the intervention group showed a 5.3% increase in prevalence of overweight and a 3.6% decrease in prevalence of obesity. Prevalence of excess weight therefore increased by 8.5% in the control group and by 1.8% in the intervention group. Reduction in body mass index increase was maintained 2 years after completion of educational intervention regardless of sex, origin, maternal obesity, and educational level of parents. Conclusions These results confirm that school-based interventions may help contain the current increase in childhood obesity (AU)

Medium-term evaluation of an educational intervention on dietary and physical exercise habits in schoolchildren: the Avall 2 study.

OBJECTIVE: To assess whether the benefits seen in nutrition, physical activity. and body mass index were maintained at 2 years of completion of the educational intervention. MATERIAL AND METHODS: An experimental, longitudinal, 4-year, two-arm, parallel study with cluster randomization to assess an intervention program aimed at children in their first year of primary schooling attending schools in the city of Granollers. Intervention consisted of promoting healthy dietary habits and increasing physical activity through the educational pedagogy Investigation, Vision, Action and Change (IVAC), applied over 2 school years (2006-2008). Weight and height of each child wee measured in situ, and families self-completed a physical activity survey and the Krece Plus quick test in 2006, 2008, and 2010. RESULTS: A greater increase in body mass index was seen in 2010 in children from the control group (2.84 ± 0.22 vs 1.96 ± 0.163 kg/m(2), <.001). Prevalence of overweight and obesity increased by 8% and 0.5% respectively in schoolchildren in the control group, while the intervention group showed a 5.3% increase in prevalence of overweight and a 3.6%decrease in prevalence of obesity. Prevalence of excess weight therefore increased by 8.5% in the control group and by 1.8% in the intervention group. Reduction in body mass indexincrease was maintained 2 years after completion of educational intervention regardless of sex, origin, maternal obesity, and educational level of parents. CONCLUSIONS: These results confirm that school-based interventions may help contain the current increase in childhood obesity.

Assessment of a school-based intervention in eating habits and physical activity in school children: the AVall study.

BACKGROUND: Obesity has become a global public health problem, which also affects children. It has been proposed that the educational interventions during childhood could be a key strategy in the prevention of obesity. OBJECTIVE: To evaluate the efficacy of an intervention on food habits and physical activity in school children. METHODS: A 2-year cluster-randomised prospective study with two parallel arms was used to evaluate an intervention programme in children in their first year of primary schooling (5-6 years of age) in schools in the city of Granollers. The intervention consisted of the promotion of healthy eating habits and physical activity by means of the educational methodology Investigation, Vision, Action and Change (IVAC). At the beginning and at the end of the study (2006 and 2008) the weight and height of each child was measured in situ, while the families were given a self-report physical activity questionnaire and the Krece Plus quick test. RESULTS: Two years after the beginning of the study, the body mass index of the children in the control group was 0.8 kg/m(2) higher than that of the intervention schools. The intervention reduced by 62% the prevalence of overweight children. Similarly, the proportion of children that ate a second piece of fruit and took part in an after-school physical activity increased in the intervention group. In the control group, the weekly consumption of fish was reduced. CONCLUSIONS: The educational intervention in healthy eating habits and physical activity in the school could contribute to lessen the current increase in child obesity.

[Weight, dietary patterns and exercise habits in first-year primary school children: the AVall study]. / Estado ponderal, hábitos alimentarios y de actividad física en escolares de primer curso de educación primaria: estudio AVall.

OBJECTIVE: To evaluate weight, dietary patterns and exercise habits in children attending the first year of primary school in the city of Granollers (Spain). METHODS: We performed a cross-sectional study of children enrolled in the schools of the city of Granollers. All the children were born in 2000. Data were collected from September to October 2006. Weight and height were measured in each schoolchild. The parents completed a questionnaire on the frequency of food intake and physical activity and the Krece Plus test. The International Obesity Task Force cut-offs for body mass index were used to define overweight and obesity. RESULTS: A total of 566 schoolchildren were included. The prevalence of overweight was 19.6% and that of obesity was 8.5%. Only 3.8% of the children had an adequate breakfast and 17.1% ate five portions of fruit and vegetables a day. Some families consumed a low amount of fruit (22%), vegetables (37%), bread/pasta/ rice/cereals (14%), fish (32%), legumes (13%) and nuts (9%). Children who had lunch at school ate more fruits (38% vs 29%), vegetables (35% vs 25%) and fish (82% vs 73%) than those who did not have lunch at school. A total of 82% of the schoolchildren exercised regularly. CONCLUSIONS: A quarter of the children who participated in the study were overweight. The schoolchildren who had lunch at school had better dietary patterns. Inappropriate family habits can determine children's dietary habits.

Estado ponderal, hábitos alimentarios y de actividad física en escolares de primer curso de educación primaria: estudio A Vall / Weight, dietary patterns and exercise habits in first-year primary school children: the A Vall study

Objetivo: Determinar el estado ponderal y los hábitos alimentarios y de actividad física de escolares de primer curso de primaria de la ciudad de Granollers. Diseño y población de estudio: Estudio transversal de los niños censados en todas las escuelas de la ciudad de Granollers, nacidos en el año 2000. En septiembre-octubre de 2006 se determinó el peso y la talla de cada niño, las familias respondieron una encuesta de frecuencia de consumo de alimentos y de actividad física y el test rápido Krece Plus. Para definir el sobrepeso y la obesidad se utilizaron los puntos de corte de índice de masa corporal propuestos por la International Obesity Task Force. Resultados: Se estudió a 566 escolares. La prevalencia de sobrepeso fue del 19,6% y la de obesidad, del 8,5%. Sólo el 3,9% de los escolares tomaban un desayuno adecuado y el 17,1% comían 5 raciones de fruta y verduras al día. A escala familiar, destaca el bajo consumo de frutas (22%), verduras (37%), pan/pasta alimenticia/arroz/cereales (14%), pescado (32%), legumbres (13%) y frutos secos (9%). Los alumnos que almorzaban en la escuela tomaban más fruta (el 38 frente al 29%), verdura (el 35 frente al 25%) y pescado (el 82 frente al 73%). El 82% de los niños realizaban actividad física de manera regular. Conclusiones: Uno de cada 4 escolares de primero de primaria presenta ya problemas de peso. Los niños que almuerzan en la escuela tienen mejores hábitos alimentarios. Los hábitos inadecuados de la familia pueden condicionar los hábitos del escolar (AU)

Objective: To evaluate weight, dietary patterns and exercise habits in children attending the first year of primary school in the city of Granollers (Spain). Methods: We performed a cross-sectional study of children enrolled in the schools of the city of Granollers. All the children were born in 2000. Data were collected from September to October 2006. Weight and height were measured in each schoolchild. The parents completed a questionnaire on the frequency of food intake and physical activity and the Krece Plus test. The International Obesity Task Force cut-offs for body mass index were used to define overweight and obesity.Results: A total of 566 schoolchildren were included. The prevalence of overweight was 19.6% and that of obesity was 8.5%. Only 3.8% of the children had an adequate breakfast and 17.1% ate five portions of fruit and vegetables a day. Some families consumed a low amount of fruit (22%), vegetables (37%), bread/pasta/rice/cereals (14%), fish (32%), legumes (13%) and nuts (9%). Children who had lunch at school ate more fruits (38% vs 29%), vegetables (35% vs 25%) and fish (82% vs 73%) than those who did not have lunch at school. A total of 82% of the schoolchildren exercised regularly. Conclusions: A quarter of the children who participated in the study were overweight. The schoolchildren who had lunch at school had better dietary patterns. Inappropriate family habits can determine children’s dietary habits (AU)

Respuesta de los autores: Carcinoma de paratiroides / No disponible

No disponible

Dificultad en el diagnóstico y el tratamiento del carcinoma de paratiroides / Difficulty in the diagnosis and treatment of parathyroid carcinoma: a case report

El carcinoma de paratiroides es una causa poco frecuente de hiperparatiroidismo primario. El principal problema de esta afección es el diagnóstico diferencial inicial entre adenoma y carcinoma de paratiroides, dado que los criterios histológicos en estos casos es difícil que ofrezcan un diagnóstico definitivo, a diferencia de otras neoplasias. No obstante, se encuentran descritas series de signos clínicos y bioquímicos de alta sospecha inicial de malignidad. Asimismo, en los casos de hiperparatiroidismo primario más aparatosos estamos obligados a pensar en esta enfermedad, que se acaba confirmando en la mayor parte de las ocasiones, incluso años después por la aparición de metástasis a distancia. El objetivo de este artículo es la descripción de un caso de hiperparatiroidismo primario severo y persistente en un paciente varón de 40 años, que años después se confirmó como secundario a un carcinoma de paratiroides (AU)

Parathyroid carcinoma is an uncommon cause of primary hyperparathyroidism. Tha main difficulty is the initial differential diagnosis between adenoma and carcinoma of the parathyroid gland because, unlike in other neoplasms, histologic criteria do provide a definitive result. However, clinical and biochemical characteristics that are highly suspicious for malignancy have been described. Moreover, parathyroid carcinoma should be suspected when the primary hyperparathyroidism is severe. In some cases the diagnosis is made several years later with detection of distant metastases. We report the case of a 40-year-old man with severe and persistent primary hyperparathyroidism, which was confirmed years later as being secondary to parathyroid carcinoma (AU)