ABSTRACT
Mild encephalopathy with a reversible splenial lesion (MERS) is a clinico-radiological syndrome characterized by a transient mild encephalopathy and MRI findings of a reversible lesion in the splenium of corpus callosum (SCC). It is classified in MERS type I and MERS type II, depending on the involvement of SCC alone or also other white matter areas. The syndrome mainly affects children and young adults; the prognosis is favorable with complete or nearly complete neurological and radiological resolution within days or weeks. The vast majority of the cases described in the literature involve Asian and Australian children. The exact pathophysiology is unknown; however, infectious-related MERS (in particular virus associated MERS) remains the most common cause of reversible splenial lesions in childhood. To the best of our knowledge, there is only one published case of MERS associated with cytomegalovirus (CMV) infection involving an Australian child. We present here the first case of a CMV-related MERS in a European Caucasian child.
Subject(s)
Brain Diseases/etiology , Corpus Callosum/pathology , Cytomegalovirus Infections/complications , Cytomegalovirus/pathogenicity , Encephalitis/etiology , Anticonvulsants/therapeutic use , Antiviral Agents/therapeutic use , Brain Diseases/diagnostic imaging , Brain Diseases/drug therapy , Brain Diseases/virology , Corpus Callosum/diagnostic imaging , Corpus Callosum/drug effects , Corpus Callosum/virology , Cytomegalovirus Infections/diagnostic imaging , Cytomegalovirus Infections/drug therapy , Electroencephalography , Encephalitis/diagnostic imaging , Encephalitis/drug therapy , Encephalitis/virology , Humans , Infant , Magnetic Resonance Imaging , MaleABSTRACT
We report the case of an 87-year-old man affected by an unresectable ameloblastoma of the right jaw that was successfully treated by definitive proton therapy up to a dose of 66 Gy in 33 fractions. Treatment was well tolerated, and there were no interruptions due to toxicity. At follow-up visits, the patient experienced complete response to treatment with no evidence of disease and complete recovery from acute side effects. In this report, we discuss the potential and possible pitfalls of proton therapy in the treatment of specific settings.
ABSTRACT
Cardiac lipomas are extremely rare neoplasms. We report the case of a 72-year-old woman with an incidental finding of a cardiac mass.
