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1.
Occurrence, biogenesis, and synthesis of biologically active carbazole alkaloids.
Schmidt, Arndt W; Reddy, Kethiri R; Knölker, Hans-Joachim.
Chem Rev ; 112(6): 3193-328, 2012 Jun 13.
Article in English | MEDLINE | ID: mdl-22480243

Subject(s)
Alkaloids/chemical synthesis , Alkaloids/isolation & purification , Carbazoles/chemistry , Alkaloids/chemistry , Alkaloids/pharmacology , Benzoquinones/chemical synthesis , Carbazoles/chemical synthesis , Carbazoles/pharmacology , Ellipticines/chemical synthesis , Furans/chemical synthesis , Indole Alkaloids/chemical synthesis , Molecular Structure , Organic Chemistry Phenomena , Pyrroles/chemical synthesis , Quinones/chemical synthesis
2.
Chemistry and biology of carbazole alkaloids.
Knölker, Hans-Joachim; Reddy, Kethiri R.
Alkaloids Chem Biol ; 65: 1-410, 2008.
Article in English | MEDLINE | ID: mdl-18499945

Subject(s)
Alkaloids/chemistry , Biochemistry/methods , Carbazoles/chemistry , Alkaloids/chemical synthesis , Animals , Chemical Phenomena , Chemistry , Chemistry, Pharmaceutical/methods , Drug Design , Humans , Models, Chemical , Molecular Conformation , Molecular Structure
3.
Synthesis and activity of carbazole derivatives against Mycobacterium tuberculosis.
Choi, Taylor A; Czerwonka, Regina; Fröhner, Wolfgang; Krahl, Micha P; Reddy, Kethiri R; Franzblau, Scott G; Knölker, Hans-Joachim.
ChemMedChem ; 1(8): 812-5, 2006 Aug.
Article in English | MEDLINE | ID: mdl-16902934

Subject(s)
Antitubercular Agents/chemistry , Antitubercular Agents/pharmacology , Carbazoles/chemistry , Mycobacterium tuberculosis/drug effects , Antitubercular Agents/chemical synthesis , Structure-Activity Relationship
4.
First enantioselective total synthesis of neocarazostatin B, determination of its absolute configuration and transformation into carquinostatin A.
Czerwonka, Regina; Reddy, Kethiri R; Baum, Elke; Knölker, Hans-Joachim.
Chem Commun (Camb) ; (7): 711-3, 2006 Feb 21.
Article in English | MEDLINE | ID: mdl-16465315

ABSTRACT

The first enantioselective total synthesis of neocarazostatin B, the determination of its absolute configuration and transformation into carquinostatin A are described.


Subject(s)
Alkaloids/chemical synthesis , Carbazoles/chemical synthesis , Carbazoles/chemistry , Models, Chemical , Models, Molecular , Stereoisomerism
5.
Isolation and synthesis of biologically active carbazole alkaloids.
Knölker, Hans-Joachim; Reddy, Kethiri R.
Chem Rev ; 102(11): 4303-427, 2002 Nov.
Article in English | MEDLINE | ID: mdl-12428991

Subject(s)
Alkaloids/chemical synthesis , Carbazoles/chemical synthesis , Rutaceae/chemistry , Alkaloids/chemistry , Alkaloids/isolation & purification , Carbazoles/chemistry , Carbazoles/isolation & purification , Cyclization , Iron/chemistry , Molybdenum/chemistry , Oxidation-Reduction , Palladium/chemistry
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