Convenient methods for the synthesis of chiral amino alcohols and amines.

Simple, convenient methods have been developed using readily available, easy-to-handle reagents to access a variety of chiral amino alcohols and amines, which have considerable potential for applications in asymmetric organic transformations. Scholars from this laboratory in India have made significant contributions to this field, which is the subject of the current review.

Toward homogeneity of chirality via selective formation of homochiral or heterochiral aggregates.

[reaction: see text] A new method of achieving homogeneity of chirality via purification of nonracemic (partially resolved) amino alcohols 1a-d and the C2 chiral diamine 2 to obtain samples of higher ee, through preparation of homochiral and heterochiral aggregates using oxalic and fumaric acids, is described.