ABSTRACT
A 38-year-old lady presented with mild fever and dry cough of 1 week duration. Her chest X-ray showed right middle lobe collapse and consolidation. CT thorax revealed a mass in the right middle lobe. Subsequent bronchoscopy showed a growth completely occluding the right middle lobe bronchus and extending proximally into bronchus intermedius. Right bilobectomy (middle and lower lobes) with lymphadenectomy was performed. All the histomorphological features were suggestive of a low-grade mucoepidermoid carcinoma (MEC). MEC is one of the very rare neoplasms of the lung comprising <1% of all lung tumours. Low-grade MEC has a better prognosis than high-grade tumour, the latter being similar to that of non-small-cell lung carcinoma.
ABSTRACT
OBJECTIVES: Resection of isolated pulmonary and hepatic metastases from colorectal cancer can offer potential cure. However, little data is available to determine the results of staged hepatic and pulmonary resections in the same patient. METHODS: We retrospectively reviewed all patients who underwent staged hepatic and pulmonary metastasectomy for colorectal cancer in our institute from September 1998 to May 2002. Probability of survival was estimated by the Kaplan-Meier method. RESULTS: Thirty-three metastasectomies (seven redo) were carried out in 26 patients. There were 19 male and 7 female patients with a mean age of 61 years (range 34-76 years). The mean disease-free interval for hepatic and pulmonary resection was 21.8 and 23.9 months, respectively. Sternotomy, thoracotomy and video assisted thoracoscopic approach were used in 3.03, 72.7 and 24.2% of patients, respectively. Wedge excision, lobectomy and pneumonectomy were carried out in 87.87, 9.09 and 3.03% of cases, respectively. There was one hospital death following acute respiratory failure after pneumonectomy. Mean follow-up was 23.3 months (range 2-71 months). The mean survival after last pulmonary resection was 34.7 months (SE 3.03 and 95% CI of 28.8-40.6). CONCLUSIONS: Our results support aggressive surgical management of pulmonary and hepatic metastases in colorectal cancer.
Subject(s)
Colorectal Neoplasms/pathology , Liver Neoplasms/secondary , Liver Neoplasms/surgery , Lung Neoplasms/secondary , Lung Neoplasms/surgery , Adult , Aged , Female , Follow-Up Studies , Hepatectomy/methods , Humans , Male , Middle Aged , Pneumonectomy/methods , Retrospective Studies , Survival Analysis , Treatment OutcomeABSTRACT
Recurrence after complete excision of non-invasive thymoma is infrequent. We report a case of recurrent thymoma in the sternum in a 76-year-old man 13 years after complete surgical resection of stage I thymoma.