ABSTRACT
Chronic cutaneous lupus erythematosus is a polymorphous autoimmune disease which may mimic some other clinical conditions, causing diagnostic difficulties. Acneiform lesions, including comedones and pitting scars are occasionally atypical presentations of cutaneous discoid lupus erythematosus.
Subject(s)
Facial Dermatoses/pathology , Lupus Erythematosus, Discoid/pathology , Adult , Anti-Bacterial Agents/therapeutic use , Chronic Disease , Facial Dermatoses/drug therapy , Female , Humans , Hydroxychloroquine/therapeutic use , Lupus Erythematosus, Discoid/drug therapy , Tetracycline/therapeutic useABSTRACT
An 83 year old woman, exhibiting severe psoriasis, was treated conventionally (phototherapy, acitretin, and cyclosporine). After poor clinical results and significant changes in laboratory procedures, those treatments were suspended. She was then being prepared to be submitted to biological treatment, when preliminary results disclosed a 30 mm PPD. Complete improvement occurred [only] after introducing prophylactic therapy for tuberculosis and anti-depressive medication.
Subject(s)
Antidepressive Agents/therapeutic use , Depressive Disorder/drug therapy , Psoriasis/drug therapy , Sertraline/therapeutic use , Aged, 80 and over , Antitubercular Agents/therapeutic use , Depressive Disorder/complications , Female , Humans , Induction Chemotherapy/methods , Isoniazid/therapeutic use , Male , Psoriasis/etiology , Tuberculosis, Cutaneous/drug therapy , Tuberculosis, Cutaneous/etiologyABSTRACT
Lúpus eritematoso cutâneo crônico é doença autoimune, com apresentações polimorfas que podem, eventualmente, mimetizar outras condições clínicas, causando dificuldade diagnóstica. Quadro acneiforme, com comedões e lesões atróficas pontuadas (pitting scars) pode constituir apresentação atípica do lúpus eritematoso cutâneo discóide.
Chronic cutaneous lupus erythematosus is a polymorphous autoimmune disease which may mimic some other clinical conditions, causing diagnostic difficulties. Acneiform lesions, including comedones and pitting scars are occasionally atypical presentations of cutaneous discoid lupus erythematosus.
Subject(s)
Adult , Female , Humans , Facial Dermatoses/pathology , Lupus Erythematosus, Discoid/pathology , Anti-Bacterial Agents/therapeutic use , Chronic Disease , Facial Dermatoses/drug therapy , Hydroxychloroquine/therapeutic use , Lupus Erythematosus, Discoid/drug therapy , Tetracycline/therapeutic useABSTRACT
Mulher idosa apresentou psoríase em placas do tipo grave, com tendência eritrodérmica, e foi submetida a tratamento de acordo com o algoritmo consensual (fototerapia, acitretina, ciclosporina). Resultados clínicos insuficientes, recorrência e agravamento do quadro laboratorial orientaram no sentido da introdução de terapia biológica. A avaliação preliminar revelou PPD de 30mm. A resolução completa das lesões se verificou quando realizada profilaxia antituberculose e administrado antidepressivo.
An 83 year old woman, exhibiting severe psoriasis, was treated conventionally (phototherapy, acitretin, and cyclosporine). After poor clinical results and significant changes in laboratory procedures, those treatments were suspended. She was then being prepared to be submitted to biological treatment, when preliminary results disclosed a 30mm PPD. Complete improvement occurred [only] after introducing prophylactic therapy for tuberculosis and anti-depressive medication.
