ABSTRACT
OBJECTIVES: The authors sought to identify strictures or hepatic artery obstruction with posterior collateral transformation in our series of liver transplantation, treatment, and evolution. The thrombosis or severe hepatic artery stenosis sometimes presents a compensation mechanism, the collateral transformation of the artery. MATERIAL AND METHODS: From April 2002 to December 2011 we collected 18 cases of collateral transformation. We analyzed data regarding the transplantation, diagnosis, treatment, clinical evolution, liver function, and Doppler-ultrasound. RESULTS: The main indication was alcoholic cirrhosis, followed by hepatocellular carcinoma - hepatitis C virus. The mean cold ischemia time was 292.2 minutes mean hot ischemia was 48.8. The anastomosis was performed on the gastroduodenal-splenic patch donor in 14 cases, the celiac trunk in 2 cases, and on grafts to the aorta in another 2. Doppler ultrasound showed 8 cases without complications, 8 with low flows, and 2 cases with alterations of the right hepatic artery. Computed tomographic (CT) angiography was performed in patients with impaired eco-Doppler and found 4 obstructions, 2 cases with kinking, 1 stenosis, and 3 normal cases. Three patients with low flows were re-operated and another re-transplanted. After diagnosis of collateral transformation, all were treated with antiplatelet agents. Two cases of angioplasty were associated. The collaterals were diagnosed 1 month to 44.8 months after transplantation. Five patients died. In the latest data, 10 patients do not have analytical alteration. The Doppler ultrasound shows 7 cases being normal and 6 with flow but low resistances. CONCLUSIONS: In our series, all patients with collateral transformation, except one who was transplanted, maintain good liver function with permeable vessels.
Subject(s)
Collateral Circulation/physiology , Hepatic Artery , Liver Transplantation/adverse effects , Thrombosis/physiopathology , Carcinoma, Hepatocellular/physiopathology , Carcinoma, Hepatocellular/surgery , Celiac Artery/surgery , Computed Tomography Angiography , Constriction, Pathologic/diagnostic imaging , Constriction, Pathologic/etiology , Constriction, Pathologic/surgery , Echocardiography, Doppler , Hepatitis C, Chronic/physiopathology , Hepatitis C, Chronic/surgery , Humans , Liver Cirrhosis, Alcoholic/physiopathology , Liver Cirrhosis, Alcoholic/surgery , Liver Neoplasms/physiopathology , Liver Neoplasms/surgery , Postoperative Complications/diagnostic imaging , Postoperative Complications/etiology , Reoperation/statistics & numerical data , Thrombosis/diagnostic imaging , Thrombosis/etiology , Tissue DonorsSubject(s)
Humans , Female , Middle Aged , Hepatic Artery/physiopathology , Hepatic Artery , Liver Transplantation/methods , Liver Transplantation/trends , Echocardiography, Doppler/methods , Echocardiography, Doppler , Carcinoma, Hepatocellular/complications , Carcinoma, Hepatocellular , Constriction, Pathologic/complications , Constriction, PathologicSubject(s)
Collateral Circulation , Hepatic Artery/physiology , Liver Transplantation , Female , Humans , Middle AgedABSTRACT
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