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Ophthalmic Surg Lasers Imaging ; 38(3): 233-7, 2007.
Article in English | MEDLINE | ID: mdl-17552391

ABSTRACT

The anatomic response to intravitreal bevacizumab injection in three patients with aggressive, posterior retinopathy of prematurity is described. In all cases, the worse eye was treated with a single intravitreal injection of 0.75 mg of bevacizumab as monotherapy or complementary to laser therapy. In 24 hours, all injected eyes showed regression of the tunica vasculosa lentis and iris vessel engorgement and disappearance of iris rigidity. In addition, plus disease and retinal proliferation began to regress. None of the eyes required additional treatment. Follow-up of up to 10 months


Subject(s)
Angiogenesis Inhibitors/therapeutic use , Antibodies, Monoclonal/therapeutic use , Retinopathy of Prematurity/drug therapy , Antibodies, Monoclonal, Humanized , Bevacizumab , Gestational Age , Humans , Infant, Newborn , Infant, Premature , Infant, Very Low Birth Weight , Injections , Treatment Outcome , Vascular Endothelial Growth Factor A/antagonists & inhibitors , Vitreous Body
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