ABSTRACT
BACKGROUND: Coronary artery spasm (CAS) is an underdiagnosed disease especially in heart transplant patients, and in those patients the etiology and pathophysiology remain largely unknown, although it has been associated with cardiac allograft vasculopathy or graft rejection. CASE PRESENTATION: We report the case of a heart-transplant patient whose cardiac graft experienced two coronary vasospasms: the first before transplantation, and the other at one-month of a postoperative course complicated by primary graft failure. CONCLUSION: Our case illustrates that a transplanted heart predisposed with coronary vasospasm may suffer from early relapse in the recipient despite of complete post-surgical autonomic denervation. Exacerbated endothelial dysfunction of the donor heart after transplant, with the addition of systemic factors in the recipient may be involved in the genesis of this puzzling phenomenon.
Subject(s)
Coronary Vasospasm/etiology , Heart Transplantation/adverse effects , Primary Graft Dysfunction/etiology , Coronary Vasospasm/diagnostic imaging , Coronary Vasospasm/physiopathology , Coronary Vasospasm/therapy , Humans , Male , Middle Aged , Primary Graft Dysfunction/diagnostic imaging , Primary Graft Dysfunction/physiopathology , Primary Graft Dysfunction/therapy , Recovery of Function , Recurrence , Risk Factors , Time Factors , Treatment OutcomeABSTRACT
This report summarises three cases of Churg-Strauss syndrome (CSS) illustrating the diagnostic challenges associated with the cardiac manifestation of this disease. Here, we illustrate the role of cardiac magnetic resonance (CMR) for diagnosis and follow-up of CSS with a focus on new non-contrast T2-weighted imaging sequences for quantification of myocardial scar tissue and quantitative T2 mapping techniques, which allow the detection of myocardial edema.
Subject(s)
Churg-Strauss Syndrome/diagnostic imaging , Heart Diseases/diagnostic imaging , Magnetic Resonance Imaging, Cine/trends , Adult , Churg-Strauss Syndrome/complications , Female , Follow-Up Studies , Heart Diseases/complications , Humans , Male , Middle AgedABSTRACT
This article reports the case of a 31 years old man who suffered from an acute pulmonary oedema after laryngospasma following extubation. This pathology, better known by anesthesiologists than internists, results primarly from a rapid rise in negative intrapleural pressure. It is not associated with previous cardio-pulmonary illness and has a begnin course with resolution within 48 hours with oxygen and positive end expiratory pressure support.
