[Treatment of primary vesicorenal reflux in adults. Apropos of 71 case reports]. / Traitement du reflux vésico-rénal primitif de l'adulte. A propos de soixante et onze observations.

The authors report a series of seventy one cases of vesico-renal reflux in adults. Renal scarring was present in 76% of the cases, and in 11.5%, the kidneys were destroyed. The reflux was eliminated in 95.5% of the cases treated by the Leadbetter-Politano, Cohen and Glenn Anderson procedures, but a failure rate of 26% was registered with the Lich Grégoir technique. 26.5% of the patients presented with persistent urinary tract infection six months after the successful surgical correction of the reflux.

[Nephrogenic metaplasia of the urothelial mucosa. Apropos of 11 cases]. / La métaplasie néphrogénique de la muqueuse urothéliale. A propos de onze observations.

The authors report eleven new cases of nephrogenic metaplasia - a substantial addition to the sixty-three cases already reported in the literature. In their series, two cases involved the ureter, and nine, the bladder. They discuss the clinical and pathological aspects of the disease, and put forward suggestions concerning different aspects of the histogenesis. They consider the possibility of introducing new terminology.

[Histoprognostic factors of non-infiltrating urothelial tumors of the bladder]. / Facteurs d'histopronostic des tumeurs urothéliales non infiltrantes de la vessie.

The authors reported a pathology and clinical study about 215 cases of non infiltrating transitional cell carcinoma of the bladder. During the successive treatments of these lesions 475 specimens were collected. 5 tumours characteristics were analyzed: size of the tumour, multiplicity, microscopic structure, grade, mitotic index. The average time of supervision was 39,6 months. 75% of the patients presented a tumour recurrence over the 5 years period and in 3% of the cases deaths were directly attributable to the tumour. Multiplicity and especially mitotic index are the only tumour characteristics which correlated well with the likelihood of new tumour occurrence. The grade and the mitotic index are the best criteria to assess the risk of recurrence as an infiltrating carcinoma. The distribution of tumour characteristics shows that this type of lesion roughly keeps the same pathological pattern during recurrences. Nevertheless there exists a cellular dedifferentiation trend as well as an increase of mitotic index.

[Primary vesical adenocarcinoma with signet ring cells or linitis plastica of the bladder. Three cases]. / Adénocarcinome vésical primitif à cellules en bague à chaton ou linite plastique de la vessie. A propos de trois observations.

Signet ring cell adenocarcinomas of the bladder are regarded as rare tumours. The authors actually think that their frequency is underrated since they report three new cases out of a range of 700 bladder tumours. Revealing signs consist in urgency pain, frequency and/or hematuria. This set of cancer is usually tardily diagnosed and therefore of very poor prognosis whatever the therapies.