ABSTRACT
AIM: To determine whether growth, feeding tolerance and infectious events of preterm infants is related to the proportion of intake of mother's own raw milk (maternal milk) versus pooled pasteurized banked breast milk (donor milk). METHODS: This is a prospective observational study of 55 premature infants born less than 32 weeks of gestational age admitted to the neonatal intensive care unit at the Children's Hospital of Toulouse during two 6-month periods from 2003 to 2005. Enrolled infants were exclusively on enteral feeds with maternal milk ± donor milk. RESULTS: Mean gestational age was 28.6 weeks (SD 1.5) and mean birth weight 1105 grams (SD 282). During the time of exclusively breast milk feeds, weight gain (g/kg/day) was correlated to the proportion of maternal milk consumed (p = 0.0048, r = 0.4). Necrotizing enterocolitis was inversely correlated to the amount of maternal milk. The amount of maternal milk did not impact on infectious events. CONCLUSION: Mother's own raw milk improves weight gain compared with donor milk in preterm infants. Lactation strategies should be sought that helps mothers to increase their milk production.
Subject(s)
Breast Feeding/methods , Cytomegalovirus Infections/prevention & control , Enterocolitis, Necrotizing/prevention & control , Infant, Premature/growth & development , Milk Banks/standards , Milk, Human/physiology , Cytomegalovirus Infections/microbiology , Enterocolitis, Necrotizing/microbiology , Female , France , Humans , Infant Nutritional Physiological Phenomena , Infant, Newborn , Lactation/physiology , Male , Milk Banks/organization & administration , Milk, Human/chemistry , Milk, Human/microbiology , Observation , Pasteurization , Prospective Studies , Weight Gain/physiologySubject(s)
Home Care Services , Patient Discharge/statistics & numerical data , France , Humans , Infant, NewbornABSTRACT
Acyclovir is a synthetic nucleoside analogue active against herpes viruses. Exposure during human pregnancy and during the neonatal period seems safe. We report a case of early necrotizing enterocolitis in a full term infant treated with acyclovir as a prophylactic therapy. The mother had herpes genitalis with preterm, premature ruture of membranes at 32 weeks of gestational age and was treated with acyclovir until vaginal delivery. Acyclovir treatment in utero and after birth is discussed as a possible cause of necrotizing enterocolitis in the infant. Acyclovir should be used only if its benefit outweighs the potential risk to the baby.
Subject(s)
Acyclovir/therapeutic use , Enterocolitis, Necrotizing/drug therapy , Herpes Genitalis/drug therapy , Antiviral Agents/therapeutic use , Enterocolitis, Necrotizing/etiology , Female , Humans , Infant, Newborn , PregnancyABSTRACT
De 2.007 amostras de sangue examinadas de cäes da cidade de Maceió-AL, foram detectados 62 (3,1 por cento) animais positivos para a presença de microfilária (mf). Em 11 cäes, escolhidos aleatoriamente, foi colhido sangue venoso para a identificaçäo específica de Dirofilaria immitis. Para tal, foram utilizadas a motilidade, o tamanho, a morfologia das mf e a presença de antígenos solúveis do parasito, sendo encontrados cinco animais portadores de D. immitis. Mosquitos da espécies Culex quinquefasciatus foram alimentados com sangue de um cäo portador de D. immitis. O desenvolvimento de formas larvárias foi obsevado nos títulos de Malpighi, confirmando a ocorrência da dirofilariose canina por D. immitis na cidade de Maceió-AL
