1.
J Am Chem Soc
; 132(23): 7854-5, 2010 Jun 16.
Article
in English
| MEDLINE
| ID: mdl-20481582
ABSTRACT
Hydrogenation of benzonitrile into benzylamine is catalyzed under very mild conditions by the ruthenium bis(dihydrogen) complex RuH(2)(H(2))(2)(PCyp(3))(2), incorporating two tricyclopentylphosphines. Two key intermediates have been isolated, resulting from the activation of benzonitrile at early stages of activation, i.e., either N-coordination through the nitrile function or first hydrogenation with benzylimine formation, followed by, thanks to C-H activation, coordination at ruthenium as an orthometalated ligand.