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1.
Curr Res Food Sci ; 8: 100773, 2024.
Article in English | MEDLINE | ID: mdl-38840806

ABSTRACT

Food adulteration is a global concern, drawing attention from safety authorities due to its potential health risks. Detecting and categorizing oil adulteration is crucial for consumer safety and food industry integrity. This research explores hyperspectral imaging (HSI) analysis to identify substandard oil adulteration at different stages. Using the non-destructive HSI Specim Fx 10 system, a method for precise and easy imaging-based fraud detection and classification was proposed. The 670 oil samples, including pure (Almond, Mustard, Coconut, Olive) and adulterated (Sunflower, Castor, Liquid Paraffin), were analyzed. The Savitzky-Golay filter preprocessed the images to remove noise and smooth spectral signatures. The oils were identified using various machine learning approaches, including Support Vector Machines, Logistic Regression, Linear Discriminant Analysis, Random Forests, Decision Trees, K-Nearest Neighbors, and Naïve Bayes with Linear Discriminant Analysis excelling in identification. Performance parameters, including precision, recall, F1-score, and overall accuracy, were calculated. The proposed method achieved a validation accuracy of 100%, outperforming numerous state-of-the-art approaches. This study introduces a robust pipeline for effective oil adulteration detection, offering a significant advancement in food safety and quality control.

2.
Food Sci Nutr ; 12(6): 4038-4048, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38873464

ABSTRACT

Gallic acid is a widely recognized bioactive compound that falls under the category of secondary polyphenolic metabolites and is fairly found in mango fruit waste, specifically in mango seed kernel (MSK). This study aimed to adopt a green extraction approach to extract this valuable compound via ultrasound-assisted extraction (UAE) without using organic solvents but only water to obtain hazard-free extracts, and the cost of extraction can be minimal. pH (2-8), solvent ratio (20-60 mL/g), temperature (30-60°C) and time (30-60 min) of extraction were the independent variables used for extraction optimization. Single-factor experiments to obtain working ranges for selected extraction variables were carried out. A central composite design using response surface methodology was used to determine the optimum condition to obtain the maximum yield of gallic acid from MSK. The optimized extraction conditions were 3.9 pH, 36.25 mL/g solvent ratio, and 39.4°C of extraction temperature for 21.3 min. As a result, the optimized yield was 5.76 ± 0.41 mg/g, which was comparably equal to and/or better than the other solvent extraction systems. The results showed that gallic acid could efficiently be extracted via UAE under these optimal conditions. It is safer than extraction systems involving hazardous solvents that can be feasibly used for its nutraceutical and therapeutic applications.

3.
Nanomaterials (Basel) ; 14(10)2024 May 08.
Article in English | MEDLINE | ID: mdl-38786783

ABSTRACT

Nowadays, magnetic materials are also drawing considerable attention in the development of innovative energy converters such as triboelectric nanogenerators (TENGs), where the introduction of magnetic materials at the triboelectric interface not only significantly enhances the energy harvesting efficiency but also promotes TENG entry into the era of intelligence and multifunction. In this review, we begin from the basic operating principle of TENGs and then summarize the recent progress in applications of magnetic materials in the design of TENG magnetic materials by categorizing them into soft ferrites and amorphous and nanocrystalline alloys. While highlighting key role of magnetic materials in and future opportunities for improving their performance in energy conversion, we also discuss the most promising choices available today and describe emerging approaches to create even better magnetic TENGs and TENG-based sensors as far as intelligence and multifunctionality are concerned. In addition, the paper also discusses the integration of magnetic TENGs as a power source for third-party sensors and briefly explains the self-powered applications in a wide range of related fields. Finally, the paper discusses the challenges and prospects of magnetic TENGs.

4.
Sci Rep ; 14(1): 10870, 2024 05 13.
Article in English | MEDLINE | ID: mdl-38740776

ABSTRACT

Pea, member of the plant family Leguminosae, play a pivotal role in global food security as essential legumes. However, their production faces challenges stemming from the detrimental impacts of abiotic stressors, leading to a concerning decline in output. Salinity stress is one of the major factors that limiting the growth and productivity of pea. However, biochar amendment in soil has a potential role in alleviating the oxidative damage caused by salinity stress. The purpose of the study was to evaluate the potential role of biochar amendment in soil that may mitigate the adverse effect of salinity stress on pea. The treatments of this study were, (a) Pea varieties; (i) V1 = Meteor and V2 = Green Grass, Salinity Stress, (b) Control (0 mM) and (ii) Salinity (80 mM) (c) Biochar applications; (i) Control, (ii) 8 g/kg soil (56 g) and (iii) 16 g/kg soil (112 g). Salinity stress demonstrated a considerable reduction in morphological parameters as Shoot and root length decreased by (29% and 47%), fresh weight and dry weight of shoot and root by (85, 63%) and (49, 68%), as well as area of leaf reduced by (71%) among both varieties. Photosynthetic pigments (chlorophyll a, b, and carotenoid contents decreased under 80 mM salinity up to (41, 63, 55 and 76%) in both varieties as compared to control. Exposure of pea plants to salinity stress increased the oxidative damage by enhancing hydrogen peroxide and malondialdehyde content by (79 and 89%), while amendment of biochar reduced their activities as, (56% and 59%) in both varieties. The activities of catalase (CAT), superoxide dismutase (SOD), and peroxidase (POD) were increased by biochar applications under salinity stress as, (49, 59, and 86%) as well as non-enzymatic antioxidants as, anthocyanin and flavonoids improved by (112 and 67%). Organic osmolytes such as total soluble proteins, sugars, and glycine betaine were increased up to (57, 83, and 140%) by biochar amendment. Among uptake of mineral ions, shoot and root Na+ uptake was greater (144 and 73%) in saline-stressed plants as compared to control, while shoot and root Ca2+ and K+ were greater up to (175, 119%) and (77, 146%) in biochar-treated plants. Overall findings revealed that 16 g/kg soil (112 g) biochar was found to be effective in reducing salinity toxicity by causing reduction in reactive oxygen species and root and shoot Na+ ions uptake and improving growth, physiological and anti-oxidative activities in pea plants (Fig. 1). Figure 1 A schematic diagram represents two different mechanisms of pea under salinity stress (control and 80 mM NaCl) with Biochar (8 and 16 g/kg soil).


Subject(s)
Charcoal , Pisum sativum , Soil , Pisum sativum/drug effects , Pisum sativum/growth & development , Pisum sativum/metabolism , Soil/chemistry , Photosynthesis/drug effects , Salt Stress/drug effects , Salinity , Chlorophyll/metabolism , Plant Roots/drug effects , Plant Roots/growth & development , Plant Roots/metabolism , Antioxidants/metabolism , Plant Leaves/drug effects , Plant Leaves/metabolism , Plant Leaves/growth & development , Plant Shoots/drug effects , Plant Shoots/growth & development , Plant Shoots/metabolism
5.
Polymers (Basel) ; 16(10)2024 May 07.
Article in English | MEDLINE | ID: mdl-38794497

ABSTRACT

In advancing the transition of the energy sector toward heightened sustainability and environmental friendliness, biopolymers have emerged as key elements in the construction of triboelectric nanogenerators (TENGs) due to their renewable sources and excellent biodegradability. The development of these TENG devices is of significant importance to the next generation of renewable and sustainable energy technologies based on carbon-neutral materials. This paper introduces the working principles, material sources, and wide-ranging applications of biopolymer-based triboelectric nanogenerators (BP-TENGs). It focuses on the various categories of biopolymers, ranging from natural sources to microbial and chemical synthesis, showcasing their significant potential in enhancing TENG performance and expanding their application scope, while emphasizing their notable advantages in biocompatibility and environmental sustainability. To gain deeper insights into future trends, we discuss the practical applications of BP-TENG in different fields, categorizing them into energy harvesting, healthcare, and environmental monitoring. Finally, the paper reveals the shortcomings, challenges, and possible solutions of BP-TENG, aiming to promote the advancement and application of biopolymer-based TENG technology. We hope this review will inspire the further development of BP-TENG towards more efficient energy conversion and broader applications.

6.
PLoS One ; 19(4): e0297529, 2024.
Article in English | MEDLINE | ID: mdl-38578792

ABSTRACT

Currently, the world faces an existential threat of climate change, and every government across the globe is trying to come up with strategies to tackle the severity of climate change in every way possible. To this end, the use of clean energy rather than fossil fuel energy sources is critical, as it can reduce greenhouse gas emissions and pave the way for carbon neutrality. This study examines the impact of the energy cleanability gap on four different climate vulnerabilities, such as ecosystem, food, health, and housing vulnerabilities, considering 47 European and non-European high-income countries. The study considers samples from 2002 to 2019. This study precedes the empirical analysis in the context of a quadratic relationship between the energy cleanability gap and climate vulnerability. The study uses system-generalized methods of the moment as the main technique, while panel quantile regression is a robustness analysis. Fixed effect and random effect models have also been incorporated. The study finds that the energy cleanability gap and all four climate vulnerabilities demonstrate a U-shaped relationship in both European and non-European countries, implying that when the energy cleanability gap increases, climate vulnerability decreases, but after reaching a certain threshold, it starts to increase. Development expenditure is found to be negatively affecting food and health vulnerabilities in European nations, while it increases food vulnerability and decreases health vulnerability in non-European nations. Regarding industrialization's impact on climate vulnerabilities, the study finds opposite effects for the European and non-European economies. On the other hand, for both groups, trade openness decreases climate vulnerabilities. Based on these results, the study recommends speeding up the energy transition process from fossil fuel energy resources towards clean energy resources to obtain carbon neutrality in both European and non-European groups.


Subject(s)
Ecosystem , Greenhouse Gases , Developed Countries , Greenhouse Gases/analysis , Economic Development , Fossil Fuels/analysis , Carbon/analysis , Carbon Dioxide/analysis , Renewable Energy
7.
Heliyon ; 10(4): e26535, 2024 Feb 29.
Article in English | MEDLINE | ID: mdl-38434083

ABSTRACT

There is serious debate among researchers regarding the sustainability implications of economic prosperity and energy dependence. Energy consumption has a critical linkage with economic growth, but it also degrades environmental quality. Therefore, it is important to investigate the relationship between economic growth, the energy mix, and environmental sustainability. However, empirical literature utilizes narrow variables to capture environmental sustainability. Because of this, this research introduces a new environmental sustainability variable using entropy weighting and combining deforestation, household carbon emissions, and life expectancy. This study examines the relationship between environmental sustainability, economic growth, and other selected variables using data from 2002 to 2019 for the G20 and its high-, upper-, and low-middle-income member countries. Since shocks in one G20 country can affect another, this study uses the Augmented Mean Group (AMG) technique for empirical analysis. The results of this study indicate that Gross Domestic Product (EG) and its square term did not support the Environmental Kuznets Curve (EKC) theory. The energy mix has a positive impact on the environmental sustainability gap across all the samples except for the upper-middle-income group. Foreign direct investment positively affects this gap, while population growth has no significant impact. These findings demonstrate that policymakers should support environmentally friendly and clean energy sources to foster long-term economic growth and sustainability.

8.
Sensors (Basel) ; 24(2)2024 Jan 14.
Article in English | MEDLINE | ID: mdl-38257606

ABSTRACT

In the constantly evolving field of medical diagnostics, triboelectric nanogenerators (TENGs) stand out as a groundbreaking innovation for simultaneously harnessing mechanical energy from micromovements and sensing stimuli from both the human body and the ambient environment. This advancement diminishes the dependence of biosensors on external power sources and paves the way for the application of TENGs in self-powered medical devices, especially in the realm of point-of-care diagnostics. In this review, we delve into the functionality of TENGs in point-of-care diagnostics. First, from the basic principle of how TENGs effectively transform subtle physical movements into electrical energy, thereby promoting the development of self-powered biosensors and medical devices that are particularly advantageous for real-time biological monitoring. Then, the adaptable design of TENGs that facilitate customization to meet individual patient needs is introduced, with a focus on their biocompatibility and safety in medical applications. Our in-depth analysis also covers TENG-based biosensor designs moving toward exceptional sensitivity and specificity in biomarker detection, for accurate and efficient diagnoses. Challenges and future prospects such as the integration of TENGs into wearable and implantable devices are also discussed. We aim for this review to illuminate the burgeoning field of TENG-based intelligent devices for continuous, real-time health monitoring; and to inspire further innovation in this captivating area of research that is in line with patient-centered healthcare.


Subject(s)
Biological Monitoring , Point-of-Care Testing , Humans , Electric Power Supplies , Electricity , Intelligence
9.
Plants (Basel) ; 12(22)2023 Nov 11.
Article in English | MEDLINE | ID: mdl-38005721

ABSTRACT

Climate-change-induced variations in temperature and rainfall patterns are a serious threat across the globe. Flooding is the foremost challenge to agricultural productivity, and it is believed to become more intense under a changing climate. Flooding is a serious form of stress that significantly reduces crop yields, and future climatic anomalies are predicted to make the problem even worse in many areas of the world. To cope with the prevailing flooding stress, plants have developed different morphological and anatomical adaptations in their roots, aerenchyma cells, and leaves. Therefore, researchers are paying more attention to identifying developed and adopted molecular-based plant mechanisms with the objective of obtaining flooding-resistant cultivars. In this review, we discuss the various physiological, anatomical, and morphological adaptations (aerenchyma cells, ROL barriers (redial O2 loss), and adventitious roots) and the phytohormonal regulation in plants under flooding stress. This review comprises ongoing innovations and strategies to mitigate flooding stress, and it also provides new insights into how this knowledge can be used to improve productivity in the scenario of a rapidly changing climate and increasing flood intensity.

10.
PLoS One ; 18(10): e0288630, 2023.
Article in English | MEDLINE | ID: mdl-37874811

ABSTRACT

This study examines the relationship between globalization, ecological footprint, innovation, and subjective wellbeing in the form of happiness, using a comprehensive assessment of OECD countries from 2008 to 2020. The study employs FGLS, Quantile, and Bootstrap Quantile regression estimation to investigate the quadratic effects of globalization, ecological footprint, and the moderating effect of innovation while controlling for renewable energy and population density. Happiness is a multidisciplinary subject, and this study focuses on the economic dimensions of happiness. The findings reveal a nonlinear relationship between ecological footprint and globalization, with negative effects on subjective wellbeing at high levels of ecological footprint and globalization. However, the moderating effect of innovation mitigates these adverse effects, indicating that innovation can help to offset the detrimental impacts of ecological footprint and globalization on subjective wellbeing. The study's implications are significant for policymakers promoting sustainable economic growth while enhancing subjective wellbeing. The findings highlight the importance of investing in innovation and sustainable development to promote subjective wellbeing in the face of increasing ecological footprint and globalization. Additionally, this research contributes to the multidisciplinary understanding of happiness and provides valuable insights for future research in this area.


Subject(s)
Happiness , Organisation for Economic Co-Operation and Development , Carbon Dioxide , Internationality , Renewable Energy , Economic Development
11.
ACS Appl Mater Interfaces ; 15(39): 46280-46291, 2023 Oct 04.
Article in English | MEDLINE | ID: mdl-37729208

ABSTRACT

Current methods for making and disposing synthetic polymers have been widely pursued and are largely unsustainable. As a part of the solution, the reversible nature of dynamic covalent bonds emerges as an extraordinarily diverse and valuable feature in the development of exotic molecules and extended structures. With these bonds, it should be possible to construct recyclable and mechanically interlocked molecular structures using relatively simple precursors with preorganized geometries. A new helicide-based elastomer network is developed here with self-healing, recycling, and degradation features using a similar concept. The best self-healing performance (100%) was noted over 10-20 min, with various H2O, HCl, and NaOH solutions that delivered mechanical properties in the 1-1.4 MPa range. For hydrolytic degradation, the parameters are defined based on the type of binding, the pH of the solutions, and the copolymer network, which endowed a degradation time of approximately 4-11 h for each prepared sample. However, due to the reversible nature of the dynamic bonds, the material showed good recyclable mechanical properties compared to the pristine samples after five consecutive cycles, which meet the requirements of recyclable materials and recyclable packaging.

12.
Environ Sci Pollut Res Int ; 30(56): 118280-118290, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37737946

ABSTRACT

Terminal heat during reproductive stages of wheat (Triticum aestivum L.) limits the productivity of the crop. Magnesium (Mg) is an essential macronutrient that is involved in many physiological and biochemical processes to affect photosynthesis and seed weight. The present study comparatively evaluated Mg applied to soil (80 kg MgSO4·7H2O ha-1) and to plant foliage (4% w/v) in improving wheat performance under terminal heat. Wheat crop was grown in two sets of treatments until the booting stage, and then one set of plants was shifted to a glasshouse (±5 °C) at the booting stage to grow until maturity in comparison to control plants kept under ambient warehouse condition. Heat stress reduced the pollen viability while foliar- and soil-applied Mg improved it by 3% and 6% under heat stress, respectively, compared to the control without Mg treatment. The 100-seed weight, spike length, and biological yield reduced by 39%, 19%, and 50% under heat stress; however, foliar and soil application increased 100-seed weight by 45% and 40%, spike length by 8% and 5%, and biological yield by 35% and 25% under heat stress, respectively. Soil Mg showed maximum SPAD chlorophyll values; however, response was statistically similar to that of foliar Mg as compared to the control without Mg supply. Membrane stability decreased (4%) due to heat stress while foliar and soil treatments improved membrane stability by 8% and 5% compared to that of the control, respectively. Thus, Mg application through soil or plant foliage can be an effective way to reduce negative impacts of terminal heat in wheat by improving pollen viability at anthesis and 100-seed weight that was attributed to increased chlorophyll contents during anthesis.


Subject(s)
Magnesium , Triticum , Magnesium/pharmacology , Temperature , Seeds , Chlorophyll/pharmacology , Soil/chemistry , Pollen , Fertilization
14.
Front Plant Sci ; 14: 1176738, 2023.
Article in English | MEDLINE | ID: mdl-37521919

ABSTRACT

Introduction: Climate change, pest infestation, and soil degradation are significantly reducing wheat (Triticum aestivum L.) yield. Wheat is cultivated in rice-wheat and cotton-wheat cropping systems and escalating global population is exerting substantial pressure on the efficiency of these systems. Conservation tillage and crop rotation could help in lowering soil degradation and pest infestation, and improving wheat yield. Methods: This three-year study evaluated soil properties, weed infestation and wheat yield under various tillage and cropping systems. Six different cropping systems, i.e., cotton-wheat, sorghum-wheat, mungbean-wheat, rice-wheat, sunflower-wheat, and fallow-wheat (control) and three tillage systems, i.e., conventional tillage (CT), zero-tillage (ZT) and minimum tillage (MT) were included in the study. Results: The individual and interactive effects of tillage and cropping systems significantly affected soil properties, weed infestation and yield of wheat crop. Overall, CT resulted in lower soil bulk density and higher porosity, while ZT behaved oppositely at all locations in this regard. Similarly, mungbean-wheat cropping system resulted in lower bulk density and higher porosity and nitrogen (N) contents, while fallow-wheat cropping system resulted in higher bulk density, and lower soil porosity and N contents. Similarly, ZT and CT resulted in higher and lower weed infestation, respectively. Likewise, lower and higher weed density and biomass were recorded in wheat-sorghum and wheat-fallow cropping systems, respectively at all locations. In the same way higher number of productive tillers, number of grains per spike, 1000-grain weight, grain yield, and economic returns of wheat crop were recorded for CT, whereas ZT resulted in lower values of these traits. Regarding interactions, wheat-mungbean cropping system with CT resulted in lower bulk density and higher porosity and N contents, whereas wheat-fallow system with ZT behaved oppositely at all locations in this regard. Similarly, higher and lower values for yield-related traits and economic returns of wheat crop were noted for mungbean-wheat cropping system under CT and fallow-wheat and sorghum-wheat cropping systems under ZT, respectively. It is concluded that the mungbean-wheat cropping system improved wheat productivity and soil health and sorghum-wheat cropping system could lower weed infestation. Therefore, these cropping systems can be practiced to lower weed infestation and improve wheat yield and economic returns.

15.
Discov Nano ; 18(1): 74, 2023 May 15.
Article in English | MEDLINE | ID: mdl-37382723

ABSTRACT

Agricultural crops are subject to a variety of biotic and abiotic stresses that adversely affect growth and reduce the yield of crop plantss. Traditional crop stress management approaches are not capable of fulfilling the food demand of the human population which is projected to reach 10 billion by 2050. Nanobiotechnology is the application of nanotechnology in biological fields and has emerged as a sustainable approach to enhancing agricultural productivity by alleviating various plant stresses. This article reviews innovations in nanobiotechnology and its role in promoting plant growth and enhancing plant resistance/tolerance against biotic and abiotic stresses and the underlying mechanisms. Nanoparticles, synthesized through various approaches (physical, chemical and biological), induce plant resistance against these stresses by strengthening the physical barriers, improving plant photosynthesis and activating plant defense mechanisms. The nanoparticles can also upregulate the expression of stress-related genes by increasing anti-stress compounds and activating the expression of defense-related genes. The unique physico-chemical characteristics of nanoparticles enhance biochemical activity and effectiveness to cause diverse impacts on plants. Molecular mechanisms of nanobiotechnology-induced tolerance to abiotic and biotic stresses have also been highlighted. Further research is needed on efficient synthesis methods, optimization of nanoparticle dosages, application techniques and integration with other technologies, and a better understanding of their fate in agricultural systems.

16.
Carbohydr Polym ; 302: 120428, 2023 Feb 15.
Article in English | MEDLINE | ID: mdl-36604090

ABSTRACT

The rising demand for chitin and chitosan in chemical, agro-food, and healthcare industries is creating a need for rapid and high-throughput analysis. The physicochemical properties of these biopolymers are greatly dependent on the degree of acetylation (DA). Conventional methods for DA determination, such as LC-MS and 1H NMR, are time-consuming when performed on many samples, and therefore efficient methods are needed. Here, high-throughput microplate-based FTIR and FT-Raman methods were compared with their manual counterparts. Partial least squares regression models were based on 30 samples of chitin and chitosan with reference DA values obtained by LC-MS and 1H NMR, and the models were validated on an independent test set of 16 samples. The overall predictive accuracy of the high-throughput methods was at the same level as the manual methods and the well-established LC-MS and 1H NMR methods. Therefore, high-throughput FTIR and FT-Raman DA determination methods have great potential to serve as fast and economical substitutes for traditional methods.


Subject(s)
Chitin , Chitosan , Chitin/chemistry , Chitosan/chemistry , Acetylation , Biopolymers , Magnetic Resonance Spectroscopy
17.
Nurs Crit Care ; 28(2): 218-224, 2023 03.
Article in English | MEDLINE | ID: mdl-35362171

ABSTRACT

BACKGROUND: The COVID-19 pandemic has affected millions and resulted in a considerable strain on healthcare systems around the world. Intensive care units (ICUs) are reported to be affected the most because significant percentage of ICU patients requires respiratory support through mechanical ventilation (MV). AIM: This study aims to examine the staffing levels and compliance with a ventilator care bundle in a single city in Pakistan. METHODS: A cross-sectional survey of 14 ICUs including medical and surgical ICUs was conducted through a self-structured questionnaire including a standardized ventilator care bundle. We assessed the compliance of ICU staff to ventilator care bundle and calculated the correlation between staffing patterns with compliance to this bundle. RESULTS: The unit response rate was 64% (7/11 hospitals). Across these seven hospitals, there were 14 functional ICUs (7 surgical and 7 medical). The Mean (SD) numbers of beds and ventilators were 8.14 (3.39) and 5.78 (3.68) while the average patient-to-nurse and patient-to-doctor ratio was 3: 1 and 5:1 respectively. The median ventilator care bundle compliance score was 26 (IQR = 21-28) out of 30, while in medical and surgical ICUs, median scores were 24 (IQR = 19-26) and 28 (IQR = 23-30) respectively. The perceived least compliant component was head elevation in ventilated patients. Correlation analysis revealed that 24 h a day, 7 days a week onsite cover of Advanced Cardiovascular Life Support certified staff was positively correlated with the ventilator care bundle score (rs  = 0.654, p value = .011). Similarly, 24-h cover of senior ICU nurses was significantly correlated with the application of chlorhexidine oral care (rs  = 0.676, p value = .008) while routine subglottic aspiration was correlated with the number of doctors (rs  = 0.636, p value = .014). CONCLUSION: Our study suggests that ICUs in Peshawar are not well staffed in comparison with international standards and the compliance of ICUs with the ventilator care bundle is suboptimal. We found only a few aspects of ventilator care bundle compliance were related to nursing and medical staffing levels. RELEVANCE TO CLINICAL PRACTICE: Critical care staffs at most of the medical ICUs in Peshawar are not compliant with the standard guidelines for patients on mechanical ventilation. Moreover, the staffing levels at these ICUs are not in accordance with international standards. However, this study suggests that staffing levels may not be the only cause of non-compliance with standard mechanical ventilator guidelines. There is an urgent need to design and implement a program that can enhance and monitor the quality of nursing care provided to mechanically ventilated patients. Lastly, nurse staffing of ICUs in Pakistan must be increased to enable high quality care and more doctors should be trained in critical care.


Subject(s)
COVID-19 , Humans , Cross-Sectional Studies , Pandemics , Intensive Care Units , Ventilators, Mechanical , Critical Care , Workforce
18.
Environ Sci Pollut Res Int ; 30(11): 29550-29565, 2023 Mar.
Article in English | MEDLINE | ID: mdl-36417063

ABSTRACT

Conserving the lives of newborns has been a long-standing issue around the world, where 2.4 million babies die in the first month of the life. The literature indicates that the important challenges of social development goals around the globe include affordable and easy access to electricity, promotion of sustainable economic development, and provision of better social services and creation of job opportunities which help in reducing infant mortality rate. This calls for the need to probe into this matter minutely and brings up the ways for reducing the infant mortality rate. The present study is an attempt to analyze the impact of rural and urban electrification and biomass energy consumption on infant mortality rate for the period 1990-2020 using the Panel Quantile Regression (PQR) approach. The results of the study show that in both developed and developing countries, biomass energy consumption has positive impact on infant mortality rate, while rural and urban electrification has proposed the inverted U-shaped relationship with infant mortality in different quantile groups. It is also concluded that few developing countries are failed to achieve the maturity of the inverted U-shaped curve while all developed countries have achieved at the maturity stage. This study recommended that for reducing the infant mortality rate, the world should discourage the use of biomass energy and promote the affordable and easy access to electricity on priority basis.


Subject(s)
Economic Development , Infant Mortality , Infant, Newborn , Infant , Humans , Biomass , Costs and Cost Analysis , Electricity
19.
Environ Dev Sustain ; : 1-19, 2022 Sep 21.
Article in English | MEDLINE | ID: mdl-36158992

ABSTRACT

Financial development is a multidimensional process that contributes to economic growth but sometimes it has a devastating effect on climate change. No country can achieve sustainable development goals without caring the environmental quality. The present study investigates the moderating role of globalization (KOF) in determining the financial development (FD) on environmental degradation in the SAARC countries from 1990 to 2020. The long-run coefficients are estimated using the panel quantile regression (PQR) approach at lower, middle and upper quantile groups. The study shows the U-shaped relationship across three quantile groups based on financial development and carbon emissions. The moderator globalization (KOF) brings up the change in the turning point and flattens before the maturity of the U-shaped curve at the middle quantile while flattens after the maturity of the U-shaped curve at the upper quantile. The study recommends that by using energy-efficient technologies, better financial sector interaction with globalization enhances the environmental quality in SAARC countries.

20.
PeerJ Comput Sci ; 8: e1014, 2022.
Article in English | MEDLINE | ID: mdl-36092003

ABSTRACT

Proteins are the core of all functions pertaining to living things. They consist of an extended amino acid chain folding into a three-dimensional shape that dictates their behavior. Currently, convolutional neural networks (CNNs) have been pivotal in predicting protein functions based on protein sequences. While it is a technology crucial to the niche, the computation cost and translational invariance associated with CNN make it impossible to detect spatial hierarchies between complex and simpler objects. Therefore, this research utilizes capsule networks to capture spatial information as opposed to CNNs. Since capsule networks focus on hierarchical links, they have a lot of potential for solving structural biology challenges. In comparison to the standard CNNs, our results exhibit an improvement in accuracy. Gene Ontology Capsule GAN (GOCAPGAN) achieved an F1 score of 82.6%, a precision score of 90.4% and recall score of 76.1%.

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