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J Pediatr Hematol Oncol ; 34(6): e261-3, 2012 Aug.
Article in English | MEDLINE | ID: mdl-22246152

ABSTRACT

Extraskeletal osteosarcoma (ESOS) is a rare malignancy, usually arising in older adults. We were unable to find reports of children or adolescents affected by an ESOS of the breast. Here, we present the case of a high-grade osteosarcoma arising in the breast of a 16-year-old girl. The tumor was treated with breast-conserving resections and adjuvant multiagent chemotherapy, based on a regimen of doxorubicin, high-dose methotrexate, cisplatin, and ifosfamide. At last follow-up, the patient was in first complete remission, 29 months after initial diagnosis.


Subject(s)
Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Bone Neoplasms/secondary , Breast Neoplasms/pathology , Chondroblastoma/secondary , Osteosarcoma/secondary , Adolescent , Bone Neoplasms/drug therapy , Breast Neoplasms/drug therapy , Chemotherapy, Adjuvant , Chondroblastoma/drug therapy , Cisplatin/administration & dosage , Doxorubicin/administration & dosage , Female , Humans , Ifosfamide/administration & dosage , Methotrexate/administration & dosage , Neoplasm Grading , Osteosarcoma/drug therapy , Treatment Outcome
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