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J Sci Food Agric ; 90(11): 1765-73, 2010 Aug 30.
Article in English | MEDLINE | ID: mdl-20564310

ABSTRACT

The evaluation of an animal is based on production records, adjusted for environmental effects, which gives a reliable estimation of its breeding value. Highly reliable daughter yield deviations are used as inputs for genetic marker evaluation. Genetic variability is explained by particular loci and background polygenes, both of which are described by the genomic breeding value selection index. Automated genotyping enables the determination of many single-nucleotide polymorphisms (SNPs) and can increase the reliability of evaluation of young animals (from 0.30 if only the pedigree value is used to 0.60 when the genomic breeding value is applied). However, the introduction of SNPs requires a mixed model with a large number of regressors, in turn requiring new algorithms for the best linear unbiased prediction and BayesB. Here, we discuss a method that uses a genomic relationship matrix to estimate the genomic breeding value of animals directly, without regressors. A one-step procedure evaluates both genotyped and ungenotyped animals at the same time, and produces one common ranking of all animals in a whole population. An augmented pedigree-genomic relationship matrix and the removal of prerequisites produce more accurate evaluations of all connected animals.


Subject(s)
Breeding , Cattle/genetics , Genetic Variation , Genome , Quantitative Trait Loci , Animals , Genetic Markers , Genotype , Models, Genetic , Pedigree , Polymorphism, Single Nucleotide , Quantitative Trait, Heritable
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