ABSTRACT
A sporadic wasting syndrome affecting beef cattle herds parasitized by Eurytrema coelomaticum is described in the State of Paraná, southern Brazil. The disease was characterized by progressive weight loss, poor body condition despite plenty of good quality forage available, and death. Annual losses ranged from 1 to 3%. The clinical course of the disease varied from 2 to 10 months after the onset of the first clinical signs. At necropsy, one of the three distinct following patterns of lesions were observed: the pancreas was of normal size and color; small, shrunken, white and markedly and diffusely firm (fibrosis); or slightly enlarged and dark with a shriveled capsular surface. Myriads of leaf-shaped trematodes of the genus Eurytrema were packed inside multiple dilated ducts with thickened, whitish fibrous walls, or the flukes were embedded in the remaining pancreatic parenchyma. Microscopic findings included extensive loss of the pancreatic parenchyma with replacement fibrosis, intralesional flukes and eggs, and ductal hyperplasia. Inflammatory reaction varied from absent to severe with the presence of a granulomatous reaction around the trematode eggs. One affected animal had high plasma amylase concentration (1580U/L) suggesting exocrine pancreatic insufficiency. Glucose blood levels were not significantly increased. We suggest that diffuse and marked fibrosis of the pancreas induced by the presence of large amounts of pancreatic flukes is the cause of the sporadic cases of chronic wasting and death of cattle in this geographic area.
Subject(s)
Cattle Diseases/parasitology , Pancreatic Diseases/veterinary , Trematoda/growth & development , Trematode Infections/veterinary , Wasting Syndrome/veterinary , Animals , Brazil/epidemiology , Cattle , Cattle Diseases/epidemiology , Cattle Diseases/pathology , Histocytochemistry/veterinary , Male , Pancreatic Diseases/epidemiology , Pancreatic Diseases/parasitology , Pancreatic Diseases/pathology , Prospective Studies , Retrospective Studies , Trematode Infections/epidemiology , Trematode Infections/parasitology , Trematode Infections/pathology , Wasting Syndrome/epidemiology , Wasting Syndrome/parasitology , Wasting Syndrome/pathologyABSTRACT
Tissue fragments from 17 non-aborted and 93 aborted fetuses were histologically studied. No histological lesions were observed in non-aborted fetuses, and 51.6 percent of the aborted fetuses presented histological lesions. The main lesions were: focal gliosis and mononuclear infiltrate in liver, CNS, lungs and muscular tissues
Subject(s)
Animals , Female , Pregnancy , Cattle , Abortion, Veterinary , CattleABSTRACT
O presente estudo teve por objetivo investigar as alteraçöes ultraestruturais da mucosa intestinas e do tecido linfóide associado na inoculaçäo experimental de Cryptosporidium sp. Doze leitöes foram inoculados experimentalmente por via oral com 1x10 elevada a sexta potência oocistos e sacrificados 3, 6, 9 e 12 dias depois. Ao exame ultraestrutural de células intestinais observou-se espessamento e irregularidade de microvilosidades, citoplasma vacuolizado e com protrusöes, edema mitocondrial, hipertrofia de organelas citoplasmáticas e do núcleo. Nas placas de Peyer observou-se ocasionalmente mitose de células linfóides, verificando-se maior número de células blásticas
