Subject(s)
Angiogenesis Inhibitors/therapeutic use , Hepatopulmonary Syndrome/drug therapy , Mycophenolic Acid/analogs & derivatives , Nitric Oxide/antagonists & inhibitors , Adolescent , Hepatopulmonary Syndrome/etiology , Humans , Male , Mycophenolic Acid/pharmacology , Mycophenolic Acid/therapeutic use , Nitric Oxide/biosynthesisABSTRACT
The authors present the case of a child with severe idiopathic pulmonary hemosiderosis who after having begun treatment with hydroxychloroquine had a significant and lasting improvement. The efficacy of this therapeutic is pointed out. They also report the occurrence of clinical exacerbation, with hemoptysis, after receiving an influenza vaccine.
Subject(s)
Hemosiderosis/drug therapy , Hydroxychloroquine/therapeutic use , Lung Diseases/drug therapy , Child , Female , Follow-Up Studies , HumansABSTRACT
Interstitial lung disease includes a group of chronic diseases characterized by alterations in alveolar walls and loss of functional alveolar-capillary units. These are rare diseases in children, mostly with an unknown cause and associated with a high morbidity and mortality due to insufficient therapeutic effectiveness. The authors report a case of a previously healthy 3 years old child who presented with wheezing and severe respiratory insufficiency following a respiratory infection. The investigation performed led to the diagnosis of chronic interstitial pneumonitis. Several treatments have been tried (corticosteroids, hydroxychloroquine, N-acetylcysteine) without any obvious improvement.
