Venous Malformation of the Parotid Gland.

Vascular malformations of the parotid gland are extremely rare. A 23-year-old female presented with tender parotid swelling with mild compressibility. Diagnosis was made by ultrasonogram and confirmed by magnetic resonance imaging. Facial nerve preserving surgical excision of the superficial parotid gland with infiltration of foam sclerosant was done.

Erratum to: Venous Malformation of the Parotid Gland.

[This corrects the article DOI: 10.1055/s-0039-1694296.].

Understanding the processus vaginalis: the abdomino scrotal hydrocoele / Entendiendo el proceso vaginal: el hidrocele abdomino-escrotal

A knowledge of the embryology and descent of the testes is essential for all clinicians. Congenital hydrocoele, though an embryologic anomaly can present in adulthood. A abdomino scrotal hydrocole must be considered when a mass in the lower abdomen co exists with a scrotal hydrocoele.

El conocimiento de la embriología y el descenso de los testículos es esencial para todos los clínicos. El hidrocele congénito, aunque es una anomalía embriológica se puede presentar en la edad adulta. Un hidrocele abdomino-escrotal debe ser considerado cuando una masa en la parte inferior del abdomen co existe con un hidrocele testicular.

Abscesses that did not respond to just incision drainage and antibiotics.

Entomophthorales are a distinct and a relatively uncommon group of fungal organism that may cause subcutaneous infection. Infection with these organisms may be misdiagnosed as a bacterial abscess and is therefore of concern. This report presents 2 such cases who presented with localized abscess in the lower extremity.

Infection with Histoplasma capsulatum in a renal transplant recipient.

With the advent of potent immunosuppressive therapies in solid organ trans-plantation, patients are more susceptible to a variety of infections with atypical pathogens and presentations. We report a renal transplant recipient with atypical presentation of histoplasmosis.

Tendon xanthomas.

Tendon xanthomas usually present over the tendo Achilles and are associated with hyperlipidaemias. A brief review of xanthomas is presented.

Fusarium solani in the post-transplant patient: an unusual fungus.

The incidence of fungal infections in post-transplant patients ranges from 2% to 50%, and more uncommon pathogens are being isolated. Earlier, the fungi seen were candida, aspergillus, and cryptococcus; and of late, histoplasma, coccidiodomycoses, and dematiaceous fungi are seen. In this article, a patient with invasive fusariosis is presented, and literature of this uncommon fungus is reviewed.

Paraganglioma neck − a neuroendocrine tumour revisited.

Paragangliomas are uncommon neck swellings, usually associated with hypertension and flushing. They occur in the neck and other amine precursor uptake and decarboxylation cell rests, and are a challenge to the anesthetist at the time of excision.

Civilian gas gangrene: a clinical challenge.

Gas gangrene due to clostridia infections is commonly seen in war injuries and is much less commonly seen in civilian life. When such problems do occur, they present a challenge to the surgeon due to the associated high morbidity and mortality associated. A case is presented where a patient developed gas gangrene in a limb consequent to trauma that had been treated surgically. It is vital to make a correct diagnosis at the earliest to limit disease progression and to avoid complications.

Von recklinghausen neurofibromatosis-pachydermatocele causing lower limb gigantism: a case report.

Gigantism of the lower limb can occur because of plexiform neurofibromas. This condition is seen with café au lait patches and multiple neurofibromatosis in this case of von Recklinghausen neurofibromatosis. We report our patient and review literature of this uncommon condition.

A multicenter trial of the efficacy and safety of tigecycline versus imipenem/cilastatin in patients with complicated intra-abdominal infections [Study ID Numbers: 3074A1-301-WW; ClinicalTrials.gov Identifier: NCT00081744].

BACKGROUND: Complicated intra-abdominal infections (cIAI) remain challenging to treat because of their polymicrobial etiology including multi-drug resistant bacteria. The efficacy and safety of tigecycline, an expanded broad-spectrum glycylcycline antibiotic, was compared with imipenem/cilastatin (IMI/CIS) in patients with cIAI. METHODS: A prospective, double-blind, multinational trial was conducted in which patients with cIAI randomly received intravenous (IV) tigecycline (100 mg initial dose, then 50 mg every 12 hours [q12h]) or IV IMI/CIS (500/500 mg q6h or adjusted for renal dysfunction) for 5 to14 days. Clinical response at the test-of-cure (TOC) visit (14-35 days after therapy) for microbiologically evaluable (ME) and microbiological modified intent-to-treat (m-mITT) populations were the co-primary efficacy endpoint populations. RESULTS: A total of 825 patients received >or= 1 dose of study drug. The primary diagnoses for the ME group were complicated appendicitis (59%), and intestinal (8.8%) and gastric/duodenal perforations (4.6%). For the ME group, clinical cure rates at TOC were 80.6% (199/247) for tigecycline versus 82.4% (210/255) for IMI/CIS (95% CI -8.4, 5.1 for non-inferiority tigecycline versus IMI/CIS). Corresponding clinical cure rates within the m-mITT population were 73.5% (227/309) for tigecycline versus 78.2% (244/312) for IMI/CIS (95% CI -11.0, 2.5). Nausea (31.0% tigecycline, 24.8% IMI/CIS [P = 0.052]), vomiting (25.7% tigecycline, 19.4% IMI/CIS [P = 0.037]), and diarrhea (21.3% tigecycline, 18.9% IMI/CIS [P = 0.435]) were the most frequently reported adverse events. CONCLUSION: This study demonstrates that tigecycline is as efficacious as imipenem/cilastatin in the treatment of patients with cIAI.

Keloids - a frustrating hurdle in wound healing.

A balance between collagen formation and degradation is essential for normal wound healing. Inadequate wound healing results in wound breakdown, and exaggeration results in hypertrophic scars and keloids. We look at the aetiological factors, the biochemical alterations and the treatment modalities for keloids, in this clinical challenge.

A retrospective study of necrotising fasciitis.

Necrotising fasciitis (NF) is an unusual though well-described soft tissue infection of the deeper tissues resulting in a progressive synergistic bacterial gangrene. In a small retrospective study in a single center, an association was observed between NF and diabetes, age, peripheral arterial disease, and high mortality.