ABSTRACT
PURPOSE: To evaluate the outcomes following bilateral ERV intraocular lens implantation with micromonovision. METHODS: 25 subjects underwent bilateral Tecnis Symfony IOL implantation with micromonovision. The dominant eye was targeted for emmetropia and the nondominant eye for myopia of -0.75 D. Uncorrected and corrected distance (UDVA, CDVA), intermediate (UIVA, CIVA), and near visual acuity (UNVA, DCNVA); reading performance; defocus curve; and contrast sensitivity were studied. Follow-ups were conducted at 1 week and 1 and 6 months postoperatively. RESULTS: At 6 months postoperatively, the mean binocular UDVA, CDVA, UNVA, and DCNVA were -0.036 ± 0.09, -0.108 ± 0.07, 0.152 ± 0.11, and 0.216 ± 0.10 logMAR, respectively. Binocular UIVA and DCIVA were 0.048 ± 0.09 and 0.104 ± 0.08 logMAR, respectively, at 60 cm and -0.044 ± 0.09 and 0.012 ± 0.09 logMAR, respectively, at 80 cm. All patients had ≥0.2 logMAR UDVA and UNVA. Reading acuity and reading speeds showed improvement over time. Between defocus range of -2.50 and +1.00 D, the visual acuity remained ≥0.2 logMAR. Contrast sensitivity scores were within the normal range. 4 patients used reading glasses for very fine print. CONCLUSION: Bilateral ERV IOL implantation leads to excellent outcomes for far and intermediate vision, satisfactory outcomes for near vision, and good tolerance to micromonovision at the end of the 6 months. This trial is registered with CTRI/2015/10/006246.
ABSTRACT
PURPOSE: To evaluate the epithelial thickness profile changes following small incision refractive lenticule extraction (SMILE) and study their correlation with the amount of myopia corrected. METHODS: Epithelial thickness was measured in nine zones with spectral-domain anterior segment optical coherence tomography (SD-OCT) across a 6-mm diameter preoperatively and at 1 day, 2 weeks, and 3 months postoperatively. The observed changes were correlated with the degree of myopia corrected. RESULTS: The study included 100 eyes from 50 eligible patients (32 females, 18 males) with a mean age of 24.4 ± 2.8 years. Thirty-eight eyes underwent SMILE for low (spherical equivalent [SE] < -4.00 diopters [D]), 44 eyes for moderate (SE -4.00 to -6.00 D), and 18 eyes for high (SE > -6.00 to -10.00 D) myopia with 6.71 ± 1.65, 6.82 ± 0.21, and 6.44 ± 0.2 mm optical zones, respectively. At 3 months, a statistically significant epithelial thickness increase was observed in the central zone (6.83% for low, 9.26% for moderate, and 12.7% for high myopia, P < .05 for all groups) and superior zone (3.98% for low, 7.82% for moderate, and 9.87% for high myopia) across all three groups, which correlated positively with the degree of myopia corrected (r(2) = 0.723 for central zone, r(2) = 0.585 for superior zone, P < .001 for both zones). None of the other zones showed any statistically significant changes at 3 months. Four eyes of two patients with high myopia (SE > -8.00 D) had regression due to significant epithelial thickening. CONCLUSIONS: Preliminary results suggest that epithelial thickness profile changes after SMILE may have an impact on the refractive outcome in the long-term postoperative period, especially in higher degrees of myopia. [J Refract Surg. 2016;32(7):473-478.].
