ABSTRACT
Genetic variants of SARS-CoV-2 have been emerging and circulating in many places across the world. Rapid detection of these variants is essential since their dissemination can impact transmission rates, diagnostic procedures, disease severity, response to vaccines or patient management. Sanger sequencing has been used as the preferred approach for variant detection among circulating human immunodeficiency and measles virus genotypes. Using primers to amplify a fragment of the SARS-CoV-2 genome encoding part of the Spike protein, we showed that Sanger sequencing allowed us to rapidly detect the introduction and spread of three distinct SARS-CoV-2 variants in two major Brazilian cities. In both cities, after the predominance of variants closely related to the virus first identified in China, the emergence of the P.2 variant was quickly followed by the identification of the P1 variant, which became dominant in less than one month after it was first detected.
ABSTRACT
Esse estudo teve como objetivo identificar e classificar os sulcos das impressões labiais obtidas, e estabelecer relação entre os tipos de sulcos presentes nas impressões labiais e o fenótipo cor da pele e o sexo. A amostra foi composta por 60 estudantes de graduação do curso de Odontologia, de ambos os sexos. Para determinação e classificação dos sulcos labiais (Tipos I, I', II, III, IV e V), fez-se uso de amostras individuais de batons para tomada das impressões em suporte de cartolina branca. O sulco labial mais comum encontrado foi o Tipo I, seguido pelo Tipo II e pelo Tipo I'. Nos sexos feminino e masculino, o Tipo I e Tipo II foram os padrões dominantes. Os sulcos do Tipo II e I` foram predominantes em melanodermas; nos faiodermas e leucoderma, no entanto, os padrões predominantes foram os Tipos I e II. Pode-se concluir que a análise da impressão labial tem o potencial para o reconhecimento do gênero de um indivíduo, embora requeira um estudo detalhado para a realização correta do queilograma... (AU)
The aim of this study was to identify and classify the grooves of lip prints obtained, and establish a relationship between the types of labial grooves present on the prints and the phenotype of skin color and gender. The sample consisted of 60 graduate students, of both sexes. For determination and classification of lip grooves (Types I, I', II, III, IV and V), individual lip printing taken from lipsticks on white cardboard were used. The most common labial groove found, according to the classification proposed by Suzuky and Tsuchihaschi (1970), was type I, followed by Type II and Type I'. In females and in males, Type I and II were the dominant patterns. The grooves of the type II and I' were prevalent in melanoderm, in faioderm and in Caucasian the predominants patterns were types I and II. It can be concluded that lip print analysis has the potential for the recognition of the gender of an individual, but requires a detailed study to correctly perform the cheilogram... (AU)
