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1.
Nicotine Tob Res ; 1(1): 59-66, 1999 Mar.
Article in English | MEDLINE | ID: mdl-11072389

ABSTRACT

This study examined the psychometric properties of the Fagerström Test for Nicotine Dependence (FTND) in a population (N = 7998) of young smokers entering US Air Force Basic Military Training (BMT). An exploratory factor analysis suggested that the FTND is comprised of two factors. The first factor, labeled Smoking Pattern, included items assessing the number of cigarettes smoked per day, time to first cigarette, difficulty refraining from smoking, and smoking when ill. The second factor, labeled Morning Smoking, consisted of two items measuring whether one smokes more in the morning and whether one would rather give up the first cigarette of the day or all others. The Smoking Pattern factor proved to have adequate internal consistency, impressive criterion-related validity, and was strongly related to smoking cessation 1 year following BMT. In contrast, the Morning Smoking factor demonstrated questionable psychometric properties and was not supported by a confirmatory factor analysis.


Subject(s)
Psychometrics/methods , Smoking/psychology , Surveys and Questionnaires , Tobacco Use Disorder/diagnosis , Adolescent , Adult , Factor Analysis, Statistical , Female , Humans , Male , Military Personnel , Reproducibility of Results , United States
2.
Ann Pharmacother ; 27(5): 575-8, 1993 May.
Article in English | MEDLINE | ID: mdl-8347906

ABSTRACT

OBJECTIVE: To report a case of high transdermal fentanyl dosage requirements in a patient with chronic cancer pain. DATA SOURCES: Clinical studies, review articles, and relevant laboratory information. CASE SUMMARY: A 42-year-old woman with cervical cancer was admitted for control of her pain. Her outpatient analgesic regimen was a continuous intravenous infusion of morphine sulfate (MS) via an ambulatory infusion device. Upon admission, supplemental doses of intravenous MS were administered in an effort to eliminate the pain. Transdermal fentanyl therapy was initiated on hospital day 1 at 100 micrograms/h and the MS continuous intravenous infusion dosage was increased. Over the next four days, the patient experienced episodes of inadequate pain control and the transdermal fentanyl dosage was increased in increments of 100 micrograms/h. On hospital day 4 the MS continuous infusion was converted to patient-controlled analgesia (PCA). The patient reported acceptable pain control with a regimen of transdermal fentanyl 500 micrograms/h and MS via PCA and she was discharged home on hospital day 7. CONCLUSIONS: This patient's high transdermal fentanyl dosage requirement was related to disease progression. She experienced an acute pain episode that may have been effectively managed by increasing the dosage of her continuous intravenous MS infusion.


Subject(s)
Fentanyl/administration & dosage , Pain/drug therapy , Uterine Cervical Neoplasms/physiopathology , Administration, Cutaneous , Adult , Carcinoma, Squamous Cell/physiopathology , Chronic Disease , Female , Fentanyl/therapeutic use , Humans , Infusions, Intravenous , Morphine/administration & dosage , Morphine/therapeutic use , Pain/etiology
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