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1.
Materials (Basel) ; 13(9)2020 May 02.
Article in English | MEDLINE | ID: mdl-32370118

ABSTRACT

Fluorescence spectroscopy has been extensively investigated for disease diagnosis. In this framework, optical tissue phantoms are widely used for validating the biomedical device system in a laboratory environment outside of clinical procedures. Moreover, it is fundamental to consider that there are several scattering components and chromophores inside biological tissues and the interplay between scattering and absorption may result in a distortion of the emitted fluorescent signal. In this work, the photophysical behaviour of a set of liquid, tissue-like phantoms containing different compositions was analysed: phosphate buffer saline (PBS) was used as the background medium, low fat milk as a scatterer, Indian ink as an absorber and protoporphyrin IX (PpIX) dissolved in dimethyl formamide (DMF) as a fluorophore. We examined the collected data in terms of the impact of surfactant Tween-20 on the background medium, scattering effects and combination of scattering and absorption within a luminescent body on PpIX. The results indicated that the intrinsic emission peaks are red shifted by the scattering particles or surfactant, whilst the scattering agent and the absorbent can alter the emission intensity substantially. We corroborated that phantoms containing higher surfactant content (>0.5% Tween 20) are essential to prepare stable aqueous phantoms.

2.
Opt Express ; 27(13): 18892-18899, 2019 Jun 24.
Article in English | MEDLINE | ID: mdl-31252824

ABSTRACT

We demonstrate a 6.5 mW single transverse and polarization mode GaAs-based oxide-confined VCSEL at 850 nm. High power is enabled by a relatively large oxide aperture and an epitaxial design for low resistance, low optical loss, and high slope efficiency VCSELs. With the oxide aperture supporting multiple polarization unrestrained transverse modes, single transverse and polarization mode operation is achieved by a transverse and polarization mode filter etched into the surface of the VCSEL. While the VCSEL is specifically designed for light source integration on a silicon photonic integrated circuit, its performance in terms of power, spectral purity, polarization, and beam properties are of great interest for a large range of applications.

3.
Opt Express ; 25(4): 4312-4325, 2017 Feb 20.
Article in English | MEDLINE | ID: mdl-28241635

ABSTRACT

We demonstrate how to optimize the performance of PAM-4 transmitters based on lumped Silicon Photonic Mach-Zehnder Modulators (MZMs) for short-reach optical links. Firstly, we analyze the trade-off that occurs between extinction ratio and modulation loss when driving an MZM with a voltage swing less than the MZM's Vπ. This is important when driver circuits are realized in deep submicron CMOS process nodes. Next, a driving scheme based upon a switched capacitor approach is proposed to maximize the achievable bandwidth of the combined lumped MZM and CMOS driver chip. This scheme allows the use of lumped MZM for high speed optical links with reduced RF driver power consumption compared to the conventional approach of driving MZMs (with transmission line based electrodes) with a power amplifier. This is critical for upcoming short-reach link standards such as 400Gb/s 802.3 Ethernet. The driver chip was fabricated using a 65nm CMOS technology and flip-chipped on top of the Silicon Photonic chip (fabricated using IMEC's ISIPP25G technology) that contains the MZM. Open eyes with 4dB extinction ratio for a 36Gb/s (18Gbaud) PAM-4 signal are experimentally demonstrated. The electronic driver chip has a core area of only 0.11mm2 and consumes 236mW from 1.2V and 2.4V supply voltages. This corresponds to an energy efficiency of 6.55pJ/bit including Gray encoder and retiming, or 5.37pJ/bit for the driver circuit only.

4.
Opt Express ; 19(26): B604-10, 2011 Dec 12.
Article in English | MEDLINE | ID: mdl-22274077

ABSTRACT

We present a novel 10G linear burst-mode receiver (LBMRx). Equipped with a PIN photodiode, a high sensitivity of -22.7 dBm (bit-error rate: 1.1x10(-3)) was achieved when handling bursts with a dynamic range of 22.7 dB (each -22.7 dBm burst was preceded by a 0 dBm burst). The LBMRx requires a 150 ns preamble for fast gain adjustment at the start of each burst and can handle bursts separated by a guard time as short as 25.6 ns. With electronic dispersion compensation, 3400 ps/nm (200 km) chromatic dispersion can be tolerated at 2dB penalty in ASE-impaired links using C-band electro-absorption modulators.

5.
Appl Opt ; 44(36): 7867-71, 2005 Dec 20.
Article in English | MEDLINE | ID: mdl-16381540

ABSTRACT

We show the importance of achieving an acceptable level of output side-mode-suppression ratio when generating pulses by using the self-seeded gain-switched technique. Experiments carried out on such pulses exhibiting poor side-mode-suppression ratios that are subsequently filtered to improve the latter demonstrate that they possess an associated level of noise. This buildup of noise with a decreasing inherent side-mode-suppression ratio is noted regardless of the improved output-filtered side-mode-suppression ratio of 35 dB that is maintained. The degradation of the signal is due to the mode partition effect and may render these pulses unsuitable for use in high-speed optical communications systems.

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