[Brucellosis in Siberia and the Far East]. / Brutsellez v Sibiri i na Dal'nem Vostoke.

Epidemiological analysis has indicated that rat and reindeer brucellosis foci are of definite value in Siberia and the Far East in the liquidation of brucellosis ones. Foci of cattle and reindeer have been first established, evidence has been provided for the epidemiological significance of fifth-biological variant B. ovis and B. suis, as well as the ecological confinement of peculiar B. rangiferi cultures to the brucellosis foci in the Arctic. To plan antibrucellosis efforts, it is necessary to take into account the incidence of human infection, as well as the insidious circulation of the bacillus in the stock farms.

[A case of human infection with brucellosis from a cat]. / Sluchai zarazheniia liudei brutsellezom ot koshki.

The epidemiological study of a focus of Brucella infection revealed that an outbreak of brucellosis occurred in a small town, and the source of this infection was a domestic cat. As the result of contacts with this cat, six persons, among them three children aged 3, 8 and 12 years, had brucellosis. In all these patients acute brucellosis was diagnosed. Simultaneously with the clinical manifestations of the disease, a rise in antibody titer from 1:50 to 1:1,600 was observed. Brucella cultures isolated from the blood of one of the patients and from the internal organs of the cat exhibited the properties, similar to those of "rodent" strains, i. e. their differential signs permit their classification with B. suis, serovar 5.

[Morphofunctional evaluation of the immunogenicity of a live brucellosis vaccine]. / Morfofunktsional'naia otsenka immunogennosti zhivoi brutselleznoi vaktsiny.

The possibility of evaluating the immunogenic potency of brucellosis vaccine BA-19 by immunological methods has been shown. Morphometry and the quantitative evaluation of globulin-producing cells in lymphoid organs by direct and indirect immunofluorescent techniques serve as informative evaluation tests. The marker method with the evaluation of lymphocyte classes by acid and alkaline phosphatases and the electrophoretic motility characteristics of T- and B-lymphocytes, used in combination with the above-mentioned methods, present information on immunogenesis. The immunoperoxidase method and the values of the opsonophagocytic index characterize the state of phagocytosis and the persistence of the antigen.

[Br. ovis sensitivity to antibiotics]. / Chuvstvitel'nost' Br. ovis k antibiotikam.

Irrespective of their geographical origin the cultures of Br. ovis are highly sensitive to tetracycline and streptomycin. The bactericidal concentrations of tetracycline for 86.6 per cent of the strains and streptomycin for 93.20 per cent of the strains were 0.02--0.04 and 0.1--0.4 gamma/ml respectively. The bactericidal effect of morphocycline, kanamycin, benzyl-penicillin, lincomycin and monomycin was less pronounced. Polymyxin M had no bactericidal effect on the Brucella even in concentrations of 200 gamma/ml. Antibiotic sensitivity of S-subcultures of Br. ovis and the initial R-variants was studied comparatively. It was found that genetically related S-subcultures of Br. ovis were more resistant to the antibiotics than the initial R-strains.