ABSTRACT
Malignant syphilis is an uncommon manifestation of secondary syphilis, in which necrotic lesions may be associated with systemic signs and symptoms. Generally it occurs in an immunosuppressed patient, mainly HIV-infected, but might be observed on those who have normal immune response. Since there is an exponential increase in the number of syphilis cases, more diagnoses of malignant syphilis must be expected. We report a case in an immunocompetent female patient.
Subject(s)
Adult , Female , Humans , Immunocompetence/immunology , Skin Ulcer/pathology , Syphilis, Cutaneous/immunology , Syphilis, Cutaneous/pathology , Anti-Bacterial Agents/therapeutic use , Penicillin G Benzathine/therapeutic use , Skin Ulcer/immunology , Syphilis, Cutaneous/drug therapy , Treatment OutcomeABSTRACT
Malignant syphilis is an uncommon manifestation of secondary syphilis, in which necrotic lesions may be associated with systemic signs and symptoms. Generally it occurs in an immunosuppressed patient, mainly HIV-infected, but might be observed on those who have normal immune response. Since there is an exponential increase in the number of syphilis cases, more diagnoses of malignant syphilis must be expected. We report a case in an immunocompetent female patient.
Subject(s)
Immunocompetence/immunology , Skin Ulcer/pathology , Syphilis, Cutaneous/immunology , Syphilis, Cutaneous/pathology , Adult , Anti-Bacterial Agents/therapeutic use , Female , Humans , Penicillin G Benzathine/therapeutic use , Skin Ulcer/immunology , Syphilis, Cutaneous/drug therapy , Treatment OutcomeABSTRACT
Pachydermodactyly is a rare and benign form of acquired digital fibromatosis characterized by the expansion of soft tissue around proximal phalanges and interphalangeal joints. The etiology remains unknown, although it is suggested that repetitive mechanic trauma like the interlacing or rubbing of the fingers can lead to skin thickening. We report a case of a young man with skin thickening around interphalangeal joints and compulsive finger manipulation habit. The histopathology disclosed hyperkeratosis, discrete papillomatosis, mild increase of fibroblasts and dermal mucinosis. The lesions regressed partially, after finger manipulation was stopped.