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Klin Khir ; (6): 31-5, 1999.
Article in Russian | MEDLINE | ID: mdl-10483186

ABSTRACT

The data about the ability of various substances to cause definite reactions in biological objects are adduced, and, in particular, about the efficacy of a small doses of antitumoral chemopreparations in experiment. The results of investigation of the application efficacy of various doses of immunomodulating agents, such as arbisol, nucleoplat, the substrate from gram-negative bacteria Yersinia enterocolitica, antitumoral vaccine from the tumoral cells are presented for the cancer chemotherapy. While application of super-small doses of an antitumoral vaccine there was noted statistically significant inhibition of tumoral growth.


Subject(s)
Adjuvants, Immunologic/administration & dosage , Biological Factors/administration & dosage , Cancer Vaccines/administration & dosage , Cisplatin/administration & dosage , DNA Adducts/administration & dosage , Neoplasms, Experimental/drug therapy , Animals , Dose-Response Relationship, Drug , Drug Screening Assays, Antitumor , Female , Male , Mice , Mice, Inbred BALB C , Mice, Inbred C57BL , Neoplasm Transplantation , Time Factors , Yersinia enterocolitica
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