ABSTRACT
Chile does not have a national registry of immunohematologic test results; there are no data on the prevalence of erythrocyte antigens and the frequency of antibodies in this population. Therefore, foreign references are used for decision-making. In this study, a standard questionnaire was used in 74 laboratories of public and private establishments. The information from tests conducted in 2015 was requested: ABO and D typing, antibody detection, antibody identification, and erythrocyte phenotype. Prevalence for the ABO-D phenotypes were obtained at the country level (D+ [94.4%] and D- [5.5%]) and differ from those recorded in the white population (85% and 15%, respectively). Positive antibody detection results were found in 0.4 and 1.3 percent of blood donors and patients, respectively; the main specificities were anti-Lea, -E, and -D in donors and anti-D, -E, and -K in patients. Inconclusive results were observed in ABO-D typing and antibody identification in donors and patients; these samples were referred to immunohematology reference laboratories for resolution. From this study, it was possible to estimate the prevalence of erythrocyte antigens and the frequency of antibodies at the national level, and this step allows us to characterize Chile's population of blood donors and transfusion recipients and to compare the results and frequencies with other populations or countries.Chile does not have a national registry of immunohematologic test results; there are no data on the prevalence of erythrocyte antigens and the frequency of antibodies in this population. Therefore, foreign references are used for decision-making. In this study, a standard questionnaire was used in 74 laboratories of public and private establishments. The information from tests conducted in 2015 was requested: ABO and D typing, antibody detection, antibody identification, and erythrocyte phenotype. Prevalence for the ABO-D phenotypes were obtained at the country level (D+ [94.4%] and D [5.5%]) and differ from those recorded in the white population (85% and 15%, respectively). Positive antibody detection results were found in 0.4 and 1.3 percent of blood donors and patients, respectively; the main specificities were anti-Lea, -E, and -D in donors and anti-D, -E, and -K in patients. Inconclusive results were observed in ABO-D typing and antibody identification in donors and patients; these samples were referred to immunohematology reference laboratories for resolution. From this study, it was possible to estimate the prevalence of erythrocyte antigens and the frequency of antibodies at the national level, and this step allows us to characterize Chile's population of blood donors and transfusion recipients and to compare the results and frequencies with other populations or countries.
Subject(s)
Blood Donors , Blood Grouping and Crossmatching , ABO Blood-Group System , Chile , Erythrocytes , Humans , IsoantibodiesABSTRACT
Los quistes esplénicos son una patología muy poco frecuente. La clasificación más utilizada en la actualidad es propuesta por Martín y los divide en verdaderos o falsos. Son más frecuentes en mujeres menores de 40 años. La mayoría son asintomáticos, y así pueden permanecer hasta su diagnóstico en un examen de rutina. Los síntomas más frecuentemente encontrados son dolor, sensación de masa abdominal y síntomas derivados de compresión de estructuras vecinas. Los métodos diagnósticos más utilizados son el TAC y la US abdominal, con lo que se alcanza una certeza diagnóstica de 80 por ciento. De las alternativas terapéuticas disponibles creemos que la esplenectomía es la indicada pues permite el estudio completo del bazo, previene probables complicaciones y se asocia a una morbilidad baja y mortalidad escasa
Subject(s)
Humans , Female , Adolescent , Epidermal Cyst/surgery , Splenectomy/statistics & numerical data , Splenic Diseases/surgery , Diagnosis, Differential , Splenomegaly/etiologyABSTRACT
El rendimiento de la espirometría depende de la precisión y confiabilidad del espirómetro, de la técnica del examen y de los valores de referencia. Existiendo diversos tipos de espirómetros, comparamos las lecturas entre dos aparatos de sello rodante (Sensor Medics modelo 922) y 2 tipo Fleisch (Vitalograph, modelo Compact), obtenidas de 16 voluntarios, 8 hombres y 8 mujeres. Se practicó en cada equipo una espirometría al día, en 4 días sucesivos. Los exámenes se hicieron de acuerdo a recomendaciones de la American Thoracic Society (ATS). No hubo diferencias significativas en las variables consideradas entre instrumentos del mismo tipo. En la comparación entre los espirómetros de sello rodante y los de tipo Fleisch, se encontraron para estos últimos, lecturas de volumen y flujo sistemáticamente inferiores (p<0,05)
