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Ter Arkh ; 92(11): 13-16, 2020 Dec 26.
Article in Russian | MEDLINE | ID: mdl-33720598

ABSTRACT

AIM: To study the clinical course, diagnosis of pertussis in pregnant women. MATERIALS AND METHODS: Under observation were 25 pregnant women with whooping cough. The age structure was dominated by patients from 6 to 35 years old, amounting to 64%. At the time of hospitalization in 2 (8%) patients the gestation period corresponded to the first trimester, in 7 (28%) II, in 9 (36%) III. In 7 (28%) patients, the diagnosis of whooping cough was made during childbirth. The following methods were used to verify pertussis: bacteriological, PCR and serological (ELISA). RESULTS AND DISCUSSION: Clinical analysis showed that pregnant women with pertussis who came to the hospital were admitted to hospital mainly in the late stages of the disease (at 45 week in 68.6% of cases). Pertussis infection in all cases was typical: in moderate form 96%, mild at 4%. In 64% of patients, whooping cough accompanied by other respiratory diseases, which were the main cause of development of bronchitis. The use of ELISA allowed to confirm the clinical diagnosis in 91.7% of patients. CONCLUSION: The course of whooping cough in pregnant women is characterized by a typical symptom complex. To improve the verification of the diagnosis, it is advisable to use modern laboratory tests (PCR, ELISA).


Subject(s)
Whooping Cough , Adolescent , Adult , Child , Cough , Enzyme-Linked Immunosorbent Assay , Female , Hospitalization , Humans , Infant , Polymerase Chain Reaction , Pregnancy , Whooping Cough/diagnosis , Whooping Cough/epidemiology , Young Adult
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