ABSTRACT
Introducción: El deterioro intelectual y neurológico progresivo (DINP) en la infancia tiene una incidencia de 0,5 por mil nacimientos. Su impacto en lo que a morbimortalidad se refiere es importante. Los objetivos de este trabajo son conocer datos demográficos del DINP, su mortalidad y las principales causas que lo originan. Material y métodos: Se trata de un estudio retrospectivo y multicéntrico llevado a cabo en diferentes hospitales de la Comunidad Valenciana (España). Definición de caso: edad inferior a 18 años con pérdida de habilidades intelectuales o del desarrollo previamente adquiridas de al menos 3 meses de duración. Resultados: Participaron 9 hospitales y se reclutaron un total de 85 casos. La edad media al inicio de los síntomas fue de 1,8 años y al diagnóstico de 3,6. En el 68% de los casos existía un retraso previo al inicio de los síntomas. La mortalidad fue del 16,4%. Se llegó a un diagnóstico en el 74% de los casos. La causa más frecuentemente encontrada fue el síndrome de Rett. El 68% de los casos diagnosticados eran debidos a una metabolopatía. Discusión: La existencia de un retraso del desarrollo previo, así como el inicio tan precoz del proceso, puede dificultar la identificación de un DINP. Al igual que el resto de series, el mayor número de casos diagnosticados corresponde a metabolopatías. Conclusiones: El DINP en la infancia tiene un inicio precoz, con un amplio porcentaje de casos que permanecen sin diagnóstico etiológico y una mortalidad elevada (AU)
Background: Progressive intellectual and neurological deterioration (PIND) in childhood has an incidence of 0.5 per thousand live births. Its impact on morbimortality is important. The aim of this work is to study the epidemiology of PIND and the most important causes of this process. Methods: A retrospective and multicentre study was carried out in different hospitals of the Valencian Community (Spain). Case definition: age less than 18 years with a progressive loss of intellectual or development abilities, previously acquired for at least 3 months. Results: Nine hospitals participated in the study and a total of 85 cases were included. The mean age at the onset of symptoms was 1.8 years, and the mean age at diagnosis was 3.6 years. In 68% of cases there was an intellectual or developmental delay before the onset of symptoms. The mortality rate was 16.4%. A diagnosis was achieved in 74% of the cases. The most frequently found cause was Rett syndrome. More than two-thirds (68%) of diagnosed cases were due to a metabolic disease. Discussion: The existence of a previous development delay and the early onset of the PIND can make it difficult to identify. Like the rest of the series, the largest number of diagnosed cases involved a metabolic disease. Conclusions: PIND has an early onset, and in a large percentage of cases the origin remains unknown and with a high mortality rate (AU)
Subject(s)
Humans , Male , Female , Child , Rett Syndrome/epidemiology , Cognition Disorders/epidemiology , Intellectual Disability/epidemiology , Disease Progression , Brain Damage, Chronic/epidemiology , Child Development Disorders, Pervasive/epidemiologyABSTRACT
BACKGROUND: Progressive intellectual and neurological deterioration (PIND) in childhood has an incidence of 0.5 per thousand live births. Its impact on morbimortality is important. The aim of this work is to study the epidemiology of PIND and the most important causes of this process. METHODS: A retrospective and multicentre study was carried out in different hospitals of the Valencian Community (Spain). CASE DEFINITION: age less than 18 years with a progressive loss of intellectual or development abilities, previously acquired for at least 3 months. RESULTS: Nine hospitals participated in the study and a total of 85 cases were included. The mean age at the onset of symptoms was 1.8 years, and the mean age at diagnosis was 3.6 years. In 68% of cases there was an intellectual or developmental delay before the onset of symptoms. The mortality rate was 16.4%. A diagnosis was achieved in 74% of the cases. The most frequently found cause was Rett syndrome. More than two-thirds (68%) of diagnosed cases were due to a metabolic disease. DISCUSSION: The existence of a previous development delay and the early onset of the PIND can make it difficult to identify. Like the rest of the series, the largest number of diagnosed cases involved a metabolic disease. CONCLUSIONS: PIND has an early onset, and in a large percentage of cases the origin remains unknown and with a high mortality rate.
Subject(s)
Developmental Disabilities/epidemiology , Intellectual Disability/epidemiology , Nervous System Diseases/epidemiology , Child , Child, Preschool , Disease Progression , Female , Humans , Infant , Male , Retrospective Studies , Spain/epidemiologySubject(s)
Mouth Mucosa , Mucositis/microbiology , Pneumonia, Mycoplasma , Child , Humans , Male , Pneumonia, Mycoplasma/diagnosis , Severity of Illness IndexABSTRACT
INTRODUCTION: Headache and sleep disorders have a high impact in children, both from the point of view of prevalence and from the perspective of the quality of life of the subjects who suffer their consequences. AIM. To determine the prevalence of sleep disorders among the child population that suffers from headaches. SUBJECTS AND METHODS: The Spanish version of the Paediatric Sleep Questionnaire was administered to a representative sample of the child and teenage population that attend the different schools in the town of Gandia. This questionnaire includes two questions about the existence of headache. RESULTS: In all, 887 subjects answered the survey (68% of respondents). The sleep disorders that are clearly associated with headache are: rhythmic movement disorders, sleep-talking, nightmares, waking up more than twice during the night, unwillingness to go to bed, early waking, delayed onset of sleep, insomnia, irregular hours of going to bed and getting up, excessive daytime sleepiness, snoring and positive screening for apnea-hypopnea syndrome. CONCLUSIONS: It is shown that the population with headaches has a greater number of sleep disorders, mainly insomnia, excessive daytime sleepiness and parasomnias. It is important to gather information about sleep habits in any child who is attended because of headache.
Subject(s)
Headache , Sleep Wake Disorders , Adolescent , Child , Child, Preschool , Comorbidity , Headache/epidemiology , Headache/physiopathology , Humans , Sleep Wake Disorders/epidemiology , Sleep Wake Disorders/physiopathology , Spain , Surveys and QuestionnairesABSTRACT
Introducción. La cefalea y los trastornos del sueño tienen un alto impacto en la población infantil, tanto desde el punto de vista de la prevalencia como desde el punto de vista de la calidad de vida de los sujetos que los presentan. Objetivo. Conocer la prevalencia de los trastornos del sueño entre la población infantil afectada de cefalea. Sujetos y métodos. Se utilizó la versión española del Pediatric Sleep Questionnaire, que se distribuyó entre una muestra representativa de la población de niños y adolescentes que acuden a los diferentes centros escolares de la ciudad de Gandía. Dicho cuestionario incluye dos preguntas acerca de la existencia de cefalea. Resultados. Respondieron a la encuesta un total de 887 sujetos (el 68% de respondedores). Las alteraciones de sueño que se asocian de forma clara con la cefalea son: trastorno del movimiento rítmico, somniloquias, pesadillas, presentar más de dos despertares nocturnos, resistencia a acostarse, despertares tempranos, retraso en el inicio del sueño, insomnio, irregularidad en el horario de levantarse y acostarse, excesiva somnolencia diurna, ronquidos y un cribado positivo para síndrome de apnea-hipopnea. Conclusiones. Se demuestra que la población afectada de cefaleas tiene un mayor número de trastornos del sueño, fundamentalmente insomnio, excesiva somnolencia diurna y parasomnias. Es importante recabar información acerca del sueño en todo niño que sea atendido a causa de cefalea (AU)
Introduction. Headache and sleep disorders have a high impact in children, both from the point of view of prevalence and from the perspective of the quality of life of the subjects who suffer their consequences. Aim. To determine the prevalence of sleep disorders among the child population that suffers from headaches. Subjects and methods. The Spanish version of the Paediatric Sleep Questionnaire was administered to a representative sample of the child and teenage population that attend the different schools in the town of Gandia. This questionnaire includes two questions about the existence of headache. Results. In all, 887 subjects answered the survey (68% of respondents). The sleep disorders that are clearly associated with headache are: rhythmic movement disorders, sleep-talking, nightmares, waking up more than twice during the night, unwillingness to go to bed, early waking, delayed onset of sleep, insomnia, irregular hours of going to bed and getting up, excessive daytime sleepiness, snoring and positive screening for apnea-hypopnea syndrome. Conclusions. It is shown that the population with headaches has a greater number of sleep disorders, mainly insomnia, excessive daytime sleepiness and parasomnias. It is important to gather information about sleep habits in any child who is attended because of headache (AU)
Subject(s)
Humans , Male , Female , Child, Preschool , Headache/epidemiology , Sleep Wake Disorders/epidemiology , Sleep Initiation and Maintenance Disorders/epidemiology , Parasomnias/epidemiology , Snoring/epidemiology , Disorders of Excessive Somnolence/epidemiology , Sleep Apnea Syndromes/epidemiology , Morbidity SurveysABSTRACT
INTRODUCTION: The evaluation of comorbidity is an important factor in the treatment of children with attention-deficit/hyperactivity disorder. Sleep disturbances are one of the most common features of this disorder. OBJECTIVE: To find out the frequency of sleep disturbances among children with attention-deficit/hyperactivity disorder. MATERIAL AND METHODS: We used the Spanish version of the Paediatric Sleep Questionnaire, which was given out to a representative sample in Gandia (Spain). RESULTS: The questionnaire was answered by 887 (68 % of the sample). The sleep disturbances that showed a clear relationship with the three ADHD variables studied are: snoring, enuresis, rhythmic movement disturbances, night awakenings, and bedtime resistance. Sleep-disorder breathing, bruxism, somniloquy, day sleepiness, early awakenings and difficulty falling sleep are associated with only one of the three variables studied. CONCLUSIONS: Our study demonstrates that the population with attention-deficit/hyperactivity disorder has more sleep disturbances. The association with the enuresis is of particular interest due to the possible clinical implications.
Subject(s)
Attention Deficit Disorder with Hyperactivity/complications , Sleep Wake Disorders/complications , Sleep Wake Disorders/epidemiology , Adolescent , Child , Cross-Sectional Studies , Female , Humans , Male , Spain/epidemiologyABSTRACT
Introducción. Uno de los aspectos clave del tratamiento de los niños con trastorno por déficit de atención e hiperactividad (TDAH) es la valoración de la comorbilidad que dicho trastorno presenta. Uno de los trastornos comórbidos que asocia son las alteraciones del sueño. Objetivo. El objetivo de este trabajo es conocer la frecuencia con la que se presentan los trastornos del sueño en la población afectada de TDAH. Material y métodos. Se utilizó la versión española del Paediatric Sleep Questionaire, que se distribuyó entre una muestra representativa de la población de estudiantes de la ciudad de Gandía. El estudio fue aprobado por el Comité de Investigación del hospital. Resultados. Contestaron la encuesta un total de 887 sujetos (68 % de respondedores). Las alteraciones del sueño que se asocian de forma clara con las tres variables del TDAH estudiadas son: ronquido (roncar más de las mitad de la noche), enuresis, trastorno del movimiento rítmico, presentar más de dos despertares nocturnos y resistencia a acostarse. Se relacionan solamente con alguna de las tres variables estudiadas el trastorno respiratorio relacionado con el sueño, bruxismo, somniloquia, excesiva somnolencia diurna, despertares precoces y responder afirmativamente a la pregunta "¿Le cuesta dormirse por la noche?". Conclusiones. Nuestro trabajo demuestra que la población afectada de TDAH tiene un mayor número de trastornos del sueño. De particular interés pensamos que es la relación con la enuresis por las implicaciones clínicas que puede tener
Introduction. The evaluation of comorbidity is an important factor in the treatment of children with attention-deficit/hyperactivity disorder. Sleep disturbances are one of the most common features of this disorder. Objective. To find out the frequency of sleep disturbances among children with attention-deficit/hyperactivity disorder. Material and methods. We used the Spanish version of the Paediatric Sleep Questionnaire, which was given out to a representative sample in Gandia (Spain). Results. The questionnaire was answered by 887 (68 % of the sample). The sleep disturbances that showed a clear relationship with the three ADHD variables studied are: snoring, enuresis, rhythmic movement disturbances, night awakenings, and bedtime resistance. Sleep-disorder breathing, bruxism, somniloquy, day sleepiness, early awakenings and difficulty falling sleep are associated with only one of the three variables studied. Conclusions. Our study demonstrates that the population with attention-deficit/hyperactivity disorder has more sleep disturbances. The association with the enuresis is of particular interest due to the possible clinical implications
Subject(s)
Humans , Male , Female , Child , Adolescent , Attention Deficit Disorder with Hyperactivity/complications , Attention Deficit Disorder with Hyperactivity/epidemiology , Sleep Wake Disorders/etiology , Sleep Wake Disorders/epidemiology , Epidemiologic Studies , Spain/epidemiologyABSTRACT
No disponible
Subject(s)
Humans , Male , Child , Muscular Diseases/complications , Hypothyroidism/complications , Diagnosis, Differential , Muscular Diseases/diagnosis , Hypothyroidism/diagnosisSubject(s)
Hypothyroidism/complications , Muscle, Striated/pathology , Muscular Diseases/etiology , Child , Humans , Hypertrophy , Male , SyndromeABSTRACT
INTRODUCTION: Knowledge of sleep patterns and sleep disturbances among healthy children is interesting, particularly, amongst other things, for carrying out comparative studies with children with certain diseases. The objective of the present study was to study sleep patterns and the prevalence of sleep disturbances among schoolchildren. METHODS: We used the Spanish version of the Pediatric Sleep Questionnaire, which was given out to a representative sample of Gandia Town. RESULTS: The prevalence of sleep disturbances were as follows: insomnia 10.5 %, daytime sleepiness 13 %, a positive score for sleep-disorder breathing 5.7 %, snoring 5.7 %, enuresis 5.3 %, sleepwalking 12.5 %, night terrors 18.4 %, nightmares 12.8 %. As regards sleep patterns, the average time for getting up was 7:45 am, the average time for going to bed was 22:13 pm, and the average sleep duration was 9 hours and 30 minutes. CONCLUSIONS: Comparison among different populations studies is difficult due to the use of different instruments to measure the same variables. Our results are similar to other studies, with the exception of sleep-disorder breathing and snoring, where the prevalences are lower in our study. The sleep patterns also did not show any differences between other published studies.
Subject(s)
Posture , Schools , Sleep Wake Disorders/epidemiology , Students/statistics & numerical data , Catchment Area, Health , Child , Disorders of Excessive Somnolence/epidemiology , Female , Humans , Male , Sleep Apnea Syndromes/epidemiology , Spain/epidemiology , Surveys and QuestionnairesABSTRACT
Introducción: El conocimiento de los patrones de sueño normales y las alteraciones de éste en una población infantil sana tiene interés, entre otras cosas, para poder realizar posteriores análisis comparativos con grupos afectados de determinadas patologías. El objetivo del presente trabajo es, por tanto, conocer los patrones normales de sueño y la prevalencia de los diferentes trastornos de éste en una población escolar. Material y métodos: Se utilizó la versión española del Pediatric Sleep Questionaire, que se distribuyó entre una muestra representativa de la población de estudiantes de la ciudad de Gandía. Resultados: Se encontró una prevalencia de insomnio del 10,5 %, somnolencia diurna del 13,9 %, un cribado positivo para el trastorno respiratorio relacionado con el sueño en el 5,7 %, ronquido en el 4,3 %, enuresis en el 5,3 %, sonambulismo en el 12,5 %, terrores nocturnos en el 18,4 % y pesadillas en el 12,8 %. Respecto a los patrones de sueño, la hora media de levantarse fue las 7:45 h; la de acostarse, las 22:13 h, y la duración media de sueño nocturno de 9 h y 30 min. Conclusiones: La comparación entre estudios poblacionales diferentes es difícil, debido a la utilización de diferentes instrumentos para medir el mismo fenómeno. Nuestros resultados son similares a los de otras series a excepción del trastorno respiratorio relacionado con el sueño y el ronquido, en el que hemos detectado una menor prevalencia de la encontrada en otras series. Los hábitos de sueño tampoco difieren mucho de otras series publicadas (AU)
Introduction: Knowledge of sleep patterns and sleep disturbances among healthy children is interesting, particularly, amongst other things, for carrying out comparatives studies with children with certain diseases. The objective of the present study was to study sleep patterns and the prevalence of sleep disturbances among schoolchildren. Methods: We used the Spanish version of the Pediatric Sleep Questionnaire, which was given out to a representative sample of Gandia Town. Results: The prevalence of sleep disturbances were as follows: insomnia 10.5 %, daytime sleepiness 13 %, a positive score for sleep-disorder breathing 5.7 %, snoring 5.7 %, enuresis 5.3 %, sleepwalking 12.5 %, night terrors 18.4 %, nightmares 12.8 %. As regards sleep patterns, the average time for getting up was 7:45 am, the average time for going to bed was 22:13 pm, and the average sleep duration was 9 hours and 30 minutes. Conclusions: Comparison among different populations studies is difficult due to the use of different instruments to measure the same variables. Our results are similar to other studies, with the exception of sleep-disorder breathing and snoring, where the prevalences are lower in our study. The sleep patterns also did not show any differences between other published studies (AU)
