ABSTRACT
PURPOSE: To assess myopia progression in Spanish children and whether treatment with low-dose atropine eye drops delays myopia progression and axial elongation. METHODS: 339 eyes of 339 Caucasian patients with myopia, aged 5 to 11 years, were examined. Participants were randomized to a treatment arm, receiving one atropine (0.01%) eye drop/day for two, and an untreated control arm. At the baseline and 2-year follow-up visits, we recorded: spherical equivalent (SE), axial length (AL), mean keratometry (Mean-K) and anterior chamber depth (ACD). We also examined the rate of children with higher myopia progression (change in SE >1 D/2 years) and identified risk factors for progression. RESULTS: In 339 eyes of the 339 children (age=7.61; SD 1.70; range 5-11 years), the mean baseline SE was-2.15 (SD 0.62) D, and AL was 24.24 (SD 0.79) mm. After 2 years, higher increases occurred in all variables except ACD in the untreated group vs. the atropine group, respectively: SE (-0.51 (SD 0.39) D vs. -0.76 (SD 0.37) D, P<0.001), AL (0.20 (SD 0.20) mm vs. 0.37 (SD 0.27) mm, P<0.001) and Mean-K (0.01 (0.28) D vs. 0.09 (0.32) D, P=0.018). Myopia progression was reduced by 32% in the treatment group. There were more progressors >1D/2y in the control group: 62/168 (36.9%) vs. 35/171 (20.5%) (P<0.001). Atropine was identified as a protective factor against myopia progression (B=1.12; 95% CI= 0.98-1.27; P=<0.001). CONCLUSION: Spanish children showed a low rate of myopia progression. Atropine 0.01% showed a significant effect in slowing the progression of both refractive error and axial elongation.
Subject(s)
Atropine , Myopia , Axial Length, Eye , Child , Child, Preschool , Cornea , Disease Progression , Double-Blind Method , Humans , Myopia/diagnosis , Myopia/drug therapy , Myopia/epidemiology , Ophthalmic Solutions , Refraction, OcularABSTRACT
CASE REPORT: A 37-year-old psychotic patient inflicted injuries to his skin and eyes in the context of an interpretational delirium with aesthetic content. He used magnifying glasses to concentrate sunlight and suffered burns to his arms and face. In the eyes, these resulted in massive iridial atrophy with loss of the sphincteric function, photic maculopathy and peripheral retinal coagulation. The macular lesion resolved spontaneously although he did not recover visual acuity. DISCUSSION: This is the first reported case of ocular self-injury secondary to sunlight. It is also the first case reporting retinal photo-coagulative lesions secondary to sunlight.
Subject(s)
Eye Burns/etiology , Iris Diseases/etiology , Iris/injuries , Psychotic Disorders/complications , Retinal Diseases/etiology , Adult , Eye Burns/diagnosis , Fluorescein Angiography , Fundus Oculi , Humans , Iris Diseases/diagnosis , Macula Lutea/pathology , Male , Retinal Diseases/diagnosis , Visual AcuityABSTRACT
Caso clínico: Paciente varón de 37 años de edad, entratamiento psiquiátrico por trastorno psicótico. Enel transcurso de un delirio de interpretación no sistematizadoy buscando un fin estético se autoindujounas lesiones en la piel y los ojos. Utilizó lupas paraconcentrar los rayos solares desarrollando en la caray los brazos quemaduras de segundo y tercer grado,y en los ojos una atrofia masiva del iris con pérdidade la función esfínter, maculopatía solar y fotocoagulaciónde la retina periférica. La lesión macularse resolvió espontáneamente aunque la agudezavisual no se recuperó.Discusión: No se ha descrito hasta ahora ningúncaso de daño solar autoinducido sin fin destructivopurificativo,ni que presente lesiones fotocoagulativasde la retina
Case report: A 37-year-old psychotic patient ;;inflicted injuries to his skin and eyes in the context ;;of an interpretational delirium with aesthetic content. ;;He used magnifying glasses to concentrate ;;sunlight and suffered burns to his arms and face. In ;;the eyes, these resulted in massive iridial atrophy ;;with loss of the sphincteric function, photic maculopathy ;;and peripheral retinal coagulation. The ;;macular lesion resolved spontaneously although he ;;did not recover visual acuity. ;;Discussion: This is the first reported case of ocular ;;self-injury secondary to sunlight. It is also the first ;;case reporting retinal photo-coagulative lesions ;;secondary to sunlight
