ABSTRACT
Cutaneous metastases of prostate cancer are extremely rare. We present 2 cases of distant cutaneous metastases at atypical locations of prostate adenocarcinoma, and highlight the value of 2 immunohistochemical stains-prostatic acid phosphatase and prostate-specific membrane antigen-that can aid diagnosis, particularly in cases with negative staining for prostate-specific antigen.
Subject(s)
Adenocarcinoma/secondary , Prostatic Neoplasms/pathology , Skin Neoplasms/secondary , Adenocarcinoma/pathology , Aged , Aged, 80 and over , Humans , Male , Skin Neoplasms/pathologyABSTRACT
Retrovesical masses in men not related to prostatic carcinoma or hyperplasia is an uncommon pathology. Rare masses or unusual manifestations of those common diseases are a diagnostic dilemma. We review our experience in three unusual retrovesical masses in men: carcinosarcoma filling a giant bladder diverticulum; cystic prostatic carcinoma; and acquired cystic dilatation of the seminal vesicle associated with a prostatic carcinoma that obstructed and invaded the vesicle. We report the imaging findings and review the literature. In our experience, the imaging findings are usually not specific for doing a precise diagnosis and biopsy procedures are necessary.
Subject(s)
Genital Diseases, Male/diagnosis , Seminal Vesicles , Aged , Carcinoma/complications , Carcinoma/diagnosis , Carcinoma/surgery , Carcinosarcoma/complications , Carcinosarcoma/diagnosis , Carcinosarcoma/surgery , Diagnosis, Differential , Genital Diseases, Male/etiology , Genital Diseases, Male/surgery , Humans , Magnetic Resonance Imaging , Male , Prostatic Hyperplasia/complications , Prostatic Hyperplasia/diagnosis , Prostatic Hyperplasia/surgery , Prostatic Neoplasms/complications , Prostatic Neoplasms/diagnosis , Prostatic Neoplasms/surgery , Seminal Vesicles/diagnostic imaging , Seminal Vesicles/pathology , Tomography, X-Ray Computed , Ultrasonography , Urinary Bladder Neoplasms/complications , Urinary Bladder Neoplasms/diagnosis , Urinary Bladder Neoplasms/surgery , UrographyABSTRACT
INTRODUCTION: Cardiac myxomas are the most frequent benign heart tumors, and have an uncertain histogenesis. An endothelial, subendocardial and an undifferentiated mesenchymal cell origin with vasoformative characteristics has been suggested. The aim of this study was to make a review the cardiac myxomas at our institution paying special attention to its histogenesis. MATERIAL AND METHODS: We reviewed the clinico-pathological features of the 13 cardiac myxomas studied at our hospital, and we stained them with immunohistochemical stains. RESULTS: The average age on presentation was 62.8 years. 12 cases were left atrial, one of them with cerebral metastasis. The average size was 6.3 cm. Microscopically all of them were composed of a myxoid-matrix with spindled cells and small neoformed vessels. The tumors were completely positive for Vimentin and randomly positive with Actin and VIII-RA. CAM 5.2 was strictly negative. CONCLUSION: These results show that these kinds of tumors are neoplasms arising from mesenchymal pluripotential cells which are capable of many types of differentiation (endothelium, etc).
