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1.
Bioorg Med Chem Lett ; 10(4): 403-6, 2000 Feb 21.
Article in English | MEDLINE | ID: mdl-10714510

ABSTRACT

A series of N6,2-disubstituted adenosine analogues have been synthesized and their functional activity measured against A2a and A1 receptors. Examples of compounds with both a lipophilic N6-substituent and amino-functionalized 2-position were highly active at the A2a receptor on the human neutrophil.


Subject(s)
Adenosine/chemistry , Adenosine/pharmacology , Purinergic P1 Receptor Agonists , Adenosine/analogs & derivatives , Anti-Inflammatory Agents/chemistry , GTP-Binding Proteins , Solubility , Structure-Activity Relationship
2.
J Exp Child Psychol ; 32(3): 459-73, 1981 Dec.
Article in English | MEDLINE | ID: mdl-7320680
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