[Cardiovascular risk factors and carotid atherosclerosis detected by ultrasonography]. / Factores de riesgo cardiovascular y aterosclerosis carotídea detectada por ultrasonografía.

OBJECTIVES: To assess the frequency of carotid atherosclerosis and its relation to cardiovascular risk factors in a general elderly population of Mexico City. MATERIAL AND METHODS: B-mode ultrasonography was performed to investigate carotid atherosclerosis in 145 CUPA (a research project) participants, between July 1993 and January 1996. The outcome was then related to cardiovascular risk factors. RESULTS: Prevalence of ultrasound-detected carotid atherosclerosis was 64.8%. Intimal-medial thickening was detected in 64 subjects (44.1%) and carotid plaques in 82 (56.5%); Fifty-two subjects had both intimal-medial thickening and plaques. However, only 8 subjects had carotid plaques with severe stenosis (5.5%). There were no significant differences in the prevalence of atherosclerotic lesions (male 61.9%, female 66.0%). Carotid atherosclerosis was significantly associated with age (p < 0.0001), high blood pressure (p < 0.001), isolated systolic hypertension (p = 0.01), hypercholesterolemia (p = 0.04), and diabetes mellitus (p = 0.06). Prevalence of carotid atherosclerosis increased progressively with the number of vascular risk factors. CONCLUSIONS: There was a high prevalence of carotid atherosclerosis in this general elderly population of Mexico City, and was almost equal to that reported in developed western countries. Age, hypertension, hypercholesterolemia, and diabetes were the strongest predictors of atherosclerosis.

[Diversity in studies of the prevalence of systemic arterial hypertension]. / Diversidad en los estudios de prevalencia de hipertensión arterial sistémica.

To evaluate the information about prevalence of hypertension at a national level, several articles published either within or outside Mexico from 1933 to 1995 were reviewed. Variables about criteria and methodology were considered: the BP readings, method used, cutting points to define hypertension, year for screen. There were 30 papers out of 7 states, 16 reporting the Federal District of Mexico, 3 from Jalisco, 3 from Yucatán and 2 from Tamaulipas, there was only one referring to the State of Mexico, one to Veracruz, one to Michoacán and another referring to Mexicans in USA; as whole population there were two, one by the Instituto Mexicano del Seguro Social and another by Secretaría de Salud. A wide variation in prevalence was found (0.47 to 30.9%) mainly attributed to different sampling, measurements and reporting methodology. Few information was disclosed regarding female and elderly populations. The trend is slightly increasing, as expected accordingly to other information sources, but the problem might actually be masked by bias interference. Most of the studies performed have contributed so far to explore the gross prevalence, but may not reach scientific evidence to base evaluations of preventive interventions. The problem may not just be happening in this country. Variability may be partially controlled following the international recommendations to record arterial blood pressure, but still, there is a lack of recommendations to uniform epidemiological reports. Otherwise the values of hypertension prevalence may not be useful for hypertension surveillance.

[Prevalence of carotid atherosclerosis in a cohort of Mexico City]. / Prevalencia de aterosclerosis carotídea en una población de la ciudad de México.

In order to investigate the prevalence of atherosclerosis in Mexico, high resolution ultrasound and color Doppler flow imaging of carotid arteries were carried out in a group of participants in CUPA project, a cohort study started in 1989 among persons 60 years and older living permanently in a high rise in México City. Imaging studies included identification of 4 atherosclerosis related abnormalities: 1) intima media thickness; 2) kinkings and tortuousness; 3) non-stenosing plaques; and 4) significant carotid stenosis (> 50%). Analysis of 198 Doppler ultrasonographic studies in 56 males and 142 females showed an overall prevalence of atherosclerosis related lesions of 65.6%, with increasing frequency by age groups: 33% in younger than 65 year-old, 71% in 65-74 years, and up to 88% in the 75 years and older group. The prevalence of high grade stenosis was low (6%) whereas the overall frequency of non-stenosing plaques and intima-media thickness was higher than 60%. Intima-media thickness was more common in males while non-stenosing plaques and high grade stenosis were more frequent in females. However, there were not significant differences among women and men when atherosclerotic lesions were analyzed by age groups. This is the first report on the prevalence of atherosclerosis in a Mexican population using ultrasonography. Findings of the investigation document the high prevalence of atherosclerosis among elderly resident in Mexico City.