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Photochem Photobiol Sci ; 13(4): 621-5, 2014 Apr.
Article in English | MEDLINE | ID: mdl-24535477

ABSTRACT

For the first time, the behaviour of tobacco cell suspensions submitted to four porphyrins was described. The potential killer effect of these photosensitizers on tobacco cells was evaluated. Biological results were correlated with photophysical properties and the reactive oxygen species production capacity of tested compounds. Surprisingly, the anionic free-base porphyrin showed the strongest phototoxic effect.


Subject(s)
Cell Death/drug effects , Nicotiana/cytology , Nicotiana/drug effects , Photosensitizing Agents/pharmacology , Porphyrins/pharmacology , Cell Death/physiology , Cell Death/radiation effects , Cell Survival/drug effects , Cell Survival/physiology , Cell Survival/radiation effects , DNA Fragmentation/drug effects , DNA Fragmentation/radiation effects , Darkness , Hydrogen Peroxide/metabolism , Light , Photochemical Processes , Photosensitizing Agents/chemistry , Porphyrins/chemistry , Reactive Oxygen Species/metabolism , Spectrum Analysis , Nicotiana/physiology , Nicotiana/radiation effects , Water/chemistry
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