ABSTRACT
Primary melanoma of the lung is an extremely rare pathological entity and sparsely reported in the literature. A 68-year-old man was admitted with 3 months history of cough, sputum production, dyspnea, hemoptysis and chest pain. The chest radiography demonstrated bilateral mass lesion and thoracal computerized (CT) showed a bilateral tissu mass with left parietal invasion. Bronchoscopy revealed a large polypoidal tumor arising from the left lower lobe bronchus, histology at bronchial biopsy revealed a malignant melanoma. Surgical biopsy of the left parietal mass was confirmed by invasive malignant melanoma. Primary melanoma of the lung represents a rare pathological entity; careful interpretation of histopathological information in correlation with all other findings from clinical studies can establish a diagnosis.
Subject(s)
Lung Neoplasms/diagnosis , Melanoma/diagnosis , Aged , Fatal Outcome , Humans , Lung Neoplasms/pathology , Male , Melanoma/pathologySubject(s)
Carcinoma, Squamous Cell/pathology , Lung Neoplasms/pathology , Skin Neoplasms/secondary , Aged , Carcinoma, Squamous Cell/diagnostic imaging , Humans , Lung Neoplasms/diagnostic imaging , Male , Radiography, Thoracic , Skin Neoplasms/diagnosis , Skin Neoplasms/diagnostic imaging , Tomography, X-Ray ComputedSubject(s)
Lung Neoplasms/diagnosis , Lymphoma, Non-Hodgkin/diagnosis , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Cyclophosphamide/therapeutic use , Doxorubicin/therapeutic use , Humans , Lung Neoplasms/diagnostic imaging , Lung Neoplasms/drug therapy , Lung Neoplasms/pathology , Lymphoma, Non-Hodgkin/diagnostic imaging , Lymphoma, Non-Hodgkin/drug therapy , Lymphoma, Non-Hodgkin/pathology , Male , Middle Aged , Neoplasm Grading , Prednisone/therapeutic use , Radiography, Thoracic , Vincristine/therapeutic useSubject(s)
Mycobacterium tuberculosis/isolation & purification , Tuberculosis/diagnosis , Adolescent , Antitubercular Agents/therapeutic use , Diagnosis, Differential , Female , Humans , Nose Diseases/diagnosis , Nose Diseases/microbiology , Psoas Abscess/diagnosis , Psoas Abscess/microbiology , Severity of Illness Index , Treatment Outcome , Tuberculosis/complications , Tuberculosis/drug therapy , Tuberculosis, Cutaneous/diagnosis , Tuberculosis, Cutaneous/microbiologyABSTRACT
Hydatid disease caused by echinococcus granulosus is still a serious problem in both underdeveloped and developing countries. Clinical signs of the disease are not specific. Most patients have a few symptoms when a hydatid cyst is discovered. Symptoms depend on its location, size and complications. Parasite can settle in every organ and tissue in the human body. We report two cases with intrathoracic extrapulmonary hydatid cyst with multiple cysts. Pathophysiology of the mode of dissemination, and surgery are discussed.
Subject(s)
Echinococcosis/diagnosis , Echinococcus granulosus , Adolescent , Animals , Developing Countries , Diagnosis, Differential , Echinococcosis/diagnostic imaging , Echinococcosis/surgery , Female , Humans , RadiographyABSTRACT
A 67 year-old-man was hospitalized due to chronic pain and a large mass on the anterior chest wall. His medical history showed chest trauma in 1970, the reconstitution of the scenario revealed there was blunt trauma with swelling and rib fracture on the same side. Physical examination revealed an isolated large anterior chest wall mass. Chest radiography showed two bilateral irregular masses, chest computed tomography showed a large right chest wall tumor with pleural effusion, nodules of the right upper lobe and tumor of the left lower lobe without mediastinal lymphadenopathy. Whole body exploration showed only the chest disease. Transthoracic biopsy showed inflammatory reaction. Surgical biopsy by anterior thoracotomy of the right mass was performed under general anesthesia. Histological and immunohistological analysis revealed lymphoid diffuse large cell proliferation with positive staining of CD 20, BCL-6 and MUM1, confirming the diagnosis of diffuse large B-cell malignant lymphoma. Chemotherapy based on CHOP-21 (cyclophosphamide, doxorubicin, vincristine, and prednisolone) was administered with good response after three cycles. The patient was discharged under surveillance in good condition after the end of chemotherapy. We report an infrequent neoplasm with an unusual and subtle clinical presentation.
