Subject(s)
Immune Tolerance , Immunization, Passive , T-Lymphocytes/immunology , Transplantation, Homologous/immunology , Animals , Antibodies, Monoclonal , Bone Marrow/immunology , Bone Marrow Transplantation/immunology , Complement System Proteins/immunology , H-2 Antigens/analysis , Mice , Mice, Inbred BALB C , Mice, Inbred C57BL , Spleen/immunology , Spleen/transplantationABSTRACT
The accuracy of mediastinal computerized tomographic scans for the staging of bronchogenic carcinoma varies between institutions. In the present study, the sensitivity rate was 57 percent, the specificity rate 69 percent, and the overall accuracy rate 64 percent, all of which were generally lower than rates reported in the recent literature. Different scanning equipment, diagnostic criteria, and patient populations may all contribute to this variance. The data in this report suggest that tumor histologic type and location also influenced the accuracy of computerized tomography. On the basis of this study and review of the literature, it is recommended that any given institution assess the accuracy of its own computerized tomographic mediastinal scans before substituting scanning for mediastinoscopy in the preoperative staging of bronchogenic carcinoma.
