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1.
Rev. esp. anestesiol. reanim ; 67(9): 516-520, nov. 2020. ilus
Article in Spanish | IBECS | ID: ibc-195347

ABSTRACT

La infección por el coronavirus asociada al síndrome de distrés respiratorio agudo severo (SARS-CoV-2) produce un síndrome clínico denominado mundialmente covid-19 que ha generado 5.940.441 infectados y 362.813 muertes hasta mayo de 20201. En estadios moderados y severos de la infección se produce una reacción sistémica del organismo caracterizada por la hiperinflamación, tormenta de citocinas y elevación de biomarcadores de daño miocárdico. Además, se ha sugerido la relación entre covid-19 y manifestaciones neurológicas. Recientes autopsias sugieren microangiopatía trombótica en múltiples órganos. Presentamos la descripción de 2 casos de pacientes con covid-19 severo, ingresados en Reanimación, que presentaron afectación cerebrovascular y fallecieron posteriormente. Se recomienda estrictamente la aplicación de profilaxis farmacológica antitrombótica en los pacientes afectados por covid-19 ingresados en cuidados críticos y se sugiere administrar dosis profilácticas por encima de la media


Coronavirus associated severe acute respiratory syndrome (SARS-CoV-2) causes a worldwide syndrome called Covid-19 that has caused 5,940,441 infections and 362,813 deaths until May 2020. In moderate and severe stages of the infection a generalized swelling, cytokine storm and an increment of the heart damage biomarkers occur. In addition, a relation between Covid-19 and neurological symptoms have been suggested. The results of autopsies suggest thrombotic microangiopathy in multiple organs. We present 2 cases of patients infected with severe Covid-19 that were hospitalized in the Reanimation Unit that presented cerebrovascular symptoms and died afterwards. A high dose prophylaxis with antithrombotic medication is recommended in patients affected by moderate to severe Covid-19


Subject(s)
Humans , Male , Middle Aged , Aged , Coronavirus Infections/complications , Pneumonia, Viral/complications , Pandemics , Betacoronavirus , Cerebral Hemorrhage/virology , Brain Ischemia/virology , Stroke/virology , Fatal Outcome , Brain Ischemia/diagnostic imaging , Stroke/diagnostic imaging , Tomography, X-Ray Computed
2.
Rev Esp Anestesiol Reanim (Engl Ed) ; 67(9): 516-520, 2020 Nov.
Article in English, Spanish | MEDLINE | ID: mdl-33012537

ABSTRACT

Coronavirus associated severe acute respiratory syndrome (SARS-CoV-2) causes a worldwide syndrome called Covid-19 that has caused 5,940,441 infections and 362,813 deaths until May 2020. In moderate and severe stages of the infection a generalized swelling, cytokine storm and an increment of the heart damage biomarkers occur. In addition, a relation between Covid-19 and neurological symptoms have been suggested. The results of autopsies suggest thrombotic microangiopathy in multiple organs. We present 2 cases of patients infected with severe Covid-19 that were hospitalized in the Reanimation Unit that presented cerebrovascular symptoms and died afterwards. A high dose prophylaxis with antithrombotic medication is recommended in patients affected by moderate to severe Covid-19.


Subject(s)
Betacoronavirus , Coronavirus Infections/complications , Hemorrhage/complications , Ischemia/complications , Pneumonia, Viral/complications , Stroke/etiology , Aged , COVID-19 , Fatal Outcome , Hemorrhage/diagnostic imaging , Humans , Ischemia/diagnostic imaging , Male , Middle Aged , Pandemics , SARS-CoV-2 , Stroke/diagnostic imaging , Thrombotic Microangiopathies/complications , Thrombotic Microangiopathies/diagnostic imaging , Tomography, X-Ray Computed
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