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[Thiol compounds in the combined therapy of prozerin poisonings]. / Tiolovye soedineniia v kombinirovannoi terapii otravlenii prozerinom.

Trinus, F P; Riabukha, T K; Chubenko, A V; Fedotenko, O I.

Farmakol Toksikol ; 46(6): 67-9, 1983.

Article in Russian | MEDLINE | ID: mdl-6653763

ABSTRACT

The authors studied the protective action of dithiols (unithiol, dithiothreitol) and their combinations with atropine in proserine poisoning. With the use of the spatial-prospective plotting the antidote efficacy of dipyroxime, atropine, dithiothreitole, and their combinations was studied and compared. A new type of potentiation was discovered upon combined use of atropine, dipyroxime and dithiothreitol.

Subject(s)

Antidotes/therapeutic use , Cholinesterase Inhibitors/poisoning , Neostigmine/poisoning , Sulfhydryl Compounds/therapeutic use , Animals , Dose-Response Relationship, Drug , Drug Evaluation, Preclinical , Drug Synergism , Drug Therapy, Combination , Rats

[Comparative study of the anti-inflammatory, analgesic and antipyretic actions of antitumor preparations]. / Sravnitel'noe izuchenie protivovospalitel'nogo, anal'geziruiushchego i zharoponizhaiushchego deistviia protivoopukholevykh preparatov.

Trinus, F P; Chernov, V A; Riabukha, T K; Sharykina, N I.

Vopr Onkol ; 26(5): 49-54, 1980.

Article in Russian | MEDLINE | ID: mdl-6966858

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal , Antineoplastic Agents/therapeutic use , Animals , Body Temperature/drug effects , Drug Evaluation, Preclinical , Edema/drug therapy , Fever/drug therapy , Lymphoma, Non-Hodgkin/drug therapy , Mice , Neoplasms, Experimental/drug therapy , Pain/drug therapy , Rats , Sarcoma, Experimental/drug therapy

[Search for nonsteroidal anti-inflammatory substances among the amides of nicotinic and isonicotinic acids]. / Poshuk nesteroïdnykh protyzapal'nykh rechovyn sered amidiv nikotynovoï ta izonikotynovoï kyslot

Riabukha, T K; Klebanov, B M; Get'man, G O; Molochinskaia, R I.

Farm Zh ; 31(1): 64-5, 1976.

Article in Ukrainian | MEDLINE | ID: mdl-1269724

Subject(s)

Amides/pharmacology , Anti-Inflammatory Agents/pharmacology , Isonicotinic Acids/pharmacology , Nicotinic Acids/pharmacology , Hydrochloric Acid/pharmacology

[Relation between the anti-inflammatory effect and inhibiting activity of monoaminoxidase inhibitors]. / Zavisimost' mezhdu protivovospalitel'nym deistviem i ingibiruiushchei aktivnost'iu blokatorov monoaminoksidazy.

Trinus, F P; Riabukha, T K.

Farmakol Toksikol ; 36(1): 84-9, 1973.

Article in Russian | MEDLINE | ID: mdl-4685161

Subject(s)

Anti-Inflammatory Agents/pharmacology , Monoamine Oxidase Inhibitors/pharmacology , Animals , Anti-Inflammatory Agents/toxicity , Hydrazines/pharmacology , Hydrazines/toxicity , Iproniazid/pharmacology , Iproniazid/toxicity , Isoniazid/pharmacology , Isoniazid/toxicity , Lethal Dose 50 , Mitochondria, Liver/drug effects , Mitochondria, Liver/enzymology , Monoamine Oxidase Inhibitors/toxicity , Pargyline/pharmacology , Pargyline/toxicity , Rats , Tranylcypromine/pharmacology , Tranylcypromine/toxicity

[A new method of measuring the volume of a rats paw]. / Novyi metod izmereniia ob"ema lapy krys.

Mokhort, N A; Riabukha, T K.

Patol Fiziol Eksp Ter ; 15(2): 101-2, 1971.

Article in Russian | MEDLINE | ID: mdl-5138370

Subject(s)

Biometry/instrumentation , Extremities/anatomy & histology , Animals , Rats

[Dependence between the chemical structure and the pharmacological activity of nitrogen containing heterocyclic guanidine derivatives]. / Zalezhnist' mizh khimichnoiu strukturoiu ta farmakolohichnoiu aktyvnistiu v riadu azotovmisnykh heterotsyklichnykh pokhidnykh huanidinu.

Trinus, F P; Mokhort, M A; Riabukha, T K.

Farm Zh ; 25(6): 66-8, 1970.

Article in Ukrainian | MEDLINE | ID: mdl-5526479

Subject(s)

Guanidines/pharmacology , Structure-Activity Relationship , Animals , Mice

[Anti-inflammatory effect of iprazid and DG-2]. / Protivovospalitel'noe deistvie iprazida i DG-2.

Riabukha, T K.

Farmakol Toksikol ; 33(2): 199-201, 1970.

Article in Russian | MEDLINE | ID: mdl-5448562

Subject(s)

Anti-Inflammatory Agents/therapeutic use , Carrageenan/antagonists & inhibitors , Edema/prevention & control , Formaldehyde/antagonists & inhibitors , Iproniazid/pharmacology , Monoamine Oxidase Inhibitors/pharmacology , Serotonin Antagonists , Adrenalectomy , Animals , Depression, Chemical , Edema/chemically induced , Iproniazid/therapeutic use , Monoamine Oxidase Inhibitors/therapeutic use , Rats , Stimulation, Chemical , Trypsin Inhibitors/pharmacology

[Effect of vasoactive compounds on respiration and contraction of isolated stria of coronary vessels]. / Vliianie vazoaktivnykh veshchestv na dykhanie i sokrashchenie izolirovannoi poloski koronarnykh sosudov.

Riabukha, T K.

Farmakol Toksikol ; 31(1): 32-4, 1968.

Article in Russian | MEDLINE | ID: mdl-4386337

Subject(s)

Coronary Vessels/drug effects , Muscle Contraction/drug effects , Parasympathomimetics/pharmacology , Respiration/drug effects , Sympathomimetics/pharmacology , Animals , Aorta/drug effects , Carbachol/antagonists & inhibitors , Carbachol/pharmacology , Cattle , Epinephrine/antagonists & inhibitors , Epinephrine/pharmacology , Ethanolamines/pharmacology , In Vitro Techniques , Iproniazid/pharmacology , Kymography , Monoamine Oxidase Inhibitors/pharmacology , Muscle, Smooth/drug effects , Oxygen Consumption/drug effects , Rabbits , Swine , Vasomotor System/drug effects

[Relationship between the structure and pharmacological action in some pyrimidine derivatives of hydrazine]. / Zavisimost' mezhdu stroemiem i farmakologicheskim deistviem v raidu nekotorykh pirimidinovykh proizvodnykh gidrazina.

Trinus, F P; Portniagina, V A; Riabukha, T K; Karp, V K.

Farmakol Toksikol ; 31(1): 37-41, 1968.

Article in Russian | MEDLINE | ID: mdl-5675345

Subject(s)

Cardiovascular System/drug effects , Hydrazines/pharmacology , Monoamine Oxidase Inhibitors/pharmacology , Pyrimidines/pharmacology , Animals , Anura , Heart/drug effects , Hydrazines/toxicity , Hypertension/chemically induced , Hypotension/chemically induced , Manometry , Mice , Pyrimidines/toxicity , Rabbits , Rats , Spectrophotometry , Spectrum Analysis , Ultraviolet Rays

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