[The use of tranexamic acid as an anesthetic component in ENT surgeries in patients with high surgical-anesthetic risk and in hemorrhagic shock intensive therapy]. / Primenenie tranéksaminovoi kisloty v kachestve komponenta anestezii pri LOR-operatsiiakh u bol'nykh vysokogo operatsionno- anesteziologicheskogo riska i pri intensivno'i terapii gemorrhagicheskogo shoka.

Experimental and clinical trials have shown that anesthesia and intensive therapy of shock incorporating tranexamic acid enhance analgesia, hyporeflexia, thus ensuring stable, adequate anesthesia which is safe under reduced doses of standard anesthesiological modalities. Application of tranexamic acid provided more favourable course of postanesthesiological and postoperative periods, decreased the number of complications and lethal outcomes compared to standard anesthesia.

[Use of nonopiate agents for anesthesia in ENT patients at high surgical-anesthesiological risk]. / Primenenie neopiatnykh sredstv dlia anestezii u LOR-bol'nykh vysokogo operatsionno-anesteziologicheskogo riska.

Optimal methods of endotracheal anesthesia using non-opiate drugs of four classes (clofelin, transamine, contrykal, ketanes) have been fundamentally grounded developed and tried in extensive and traumatic operations for ENT malignant and vascular tumors as well as inflammation in patients of high anesthesiological operative risk. The drugs were used in 174 patients including 13 children. 87.9% of the patients had concomitant diseases: blood hypertension, coronary heart disease, chronic nonspecific pulmonary diseases, bronchial asthma, asthmatic bronchitis, diabetes mellitus, anemia. Adequate stable anesthesia was achieved in reduced dosage of conventional anesthesiological agents.