[Comparative efficacy of two topical formulations containing 10% fipronil on the control of Ctenocephalides felis felis on cats]. / Eficacia comparativa de formulacoes de uso topico contendo fipronil 10% no control de Ctenocephalides felis felis em gatos.

The goal of the present study was to evaluate the comparative efficacy of two topical formulations containing 10% fipronil on the control of Ctenocephalides felis felis on cats. The trial was performed at the Laboratory of Experimental Chemotherapy in Veterinary Parasitology from the Department of Animal Parasitology of the Institute of Veterinary of the Universidade Federal Rural do Rio de Janeiro. Eighteen mixed-breed cats were divided in three groups of six animals each. One group remained without treatment (control). The other groups received as treatment the two topical formulations, a commercial reference and the novel one, both containing 10% fipronil. Treated animals received 0.5 mL of product along their cervical region. Cats were infested on days - 2, +5, +12, +19, +26 and +33. Evaluations were made using the "comb test". The first one was undertaken 4 days after the initial infestation (day +2), and others 48 hours after following infestations (days +7, +14, +21, +28 and + 35). Both tested formulations had satisfactory efficacy until day + 35. No differences were observed comparing the efficacy levels between both formulations throughout the experimental period. The novel topical 10% fipronil formulation presented desirable efficacy on the control of C. f. felis on cats.

Eficácia comparativa de duas formulações de uso tópico contendo fipronil 10 por cento no controle de Ctenocephalides felis felis em gatos / Comparative efficacy of two topical formulations containing 10 percent fipronil on the control of Ctenocephalides felis felis on cats

No presente trabalho, foram avaliadas, comparativamente, duas formulações comerciais tópicas, contendo 10 por cento de fipronil, para o controle da pulga Ctenocephalides felis felis em gatos. O experimento foi realizado no Laboratório de Quimioterapia Experimental em Parasitologia Veterinária do Departamento de Parasitologia Animal, Instituto de Veterinária, da Universidade Federal Rural do Rio de Janeiro. Foram empregados 18 gatos, sem raça definida, divididos em três grupos de seis. Um grupo permaneceu sem tratamento (controle), e os demais foram medicados com uma formulação referência do mercado veterinário ou com uma nova formulação em teste. Os animais tratados receberam 0,5 mL do produto ao longo da região dorso-cervical e foram infestados nos dias - 2, +5, +12, +19, +26 e +33. A primeira avaliação foi realizada quatro dias após a primeira infestação e, as demais, 48 horas após cada infestação, por meio do comb test. Ambas as formulações testadas foram eficazes até o dia +35 após o tratamento, não havendo diferenças entre seus níveis de eficácia ao longo do período experimental. A nova formulação, contendo fipronil a 10 por cento, apresentou a eficácia desejada no controle de C. f. felis em gatos.

The goal of the present study was to evaluate the comparative efficacy of two topical formulations containing 10 percent fipronil on the control of Ctenocephalides felis felis on cats. The trial was performed at the Laboratory of Experimental Chemotherapy in Veterinary Parasitology from the Department of Animal Parasitology of the Institute of Veterinary of the Universidade Federal Rural do Rio de Janeiro. Eighteen mixed-breed cats were divided in three groups of six animals each. One group remained without treatment (control). The other groups received as treatment the two topical formulations, a commercial reference and the novel one, both containing 10 percent fipronil. Treated animals received 0.5 mL of product along their cervical region. Cats were infested on days - 2, +5, +12, +19, +26 and +33. Evaluations were made using the "comb test". The first one was undertaken 4 days after the initial infestation (day +2), and others 48 hours after following infestations (days +7, +14, +21, +28 and + 35). Both tested formulations had satisfactory efficacy until day + 35. No differences were observed comparing the efficacy levels between both formulations troughout the experimental period. The novel topical 10 percent fipronil formulation presented desirable efficacy on the control of C. f. felis on cats.

[Efficacy of the pyrethroid permethrin on the control of Psoroptes ovis (Hering, 1838) (Acari:Psoroptidae) in naturally infested rabbits (Oryctolagus cuniculus)]. / Eficácia do piretróide permetrina no controle de Psoroptes ovis (Hering, 1838) (Acari: Psoroptidae) em coelhos (Oryctolagus cuniculus) naturalmente infestados.

The goal of the present study was to evaluate the efficacy of a spray formulation containing 2% of the pyrethroid permethrin on the control of Psoroptes ovis in naturally infested rabbits. Ten rabbits, presenting clinical signs of psoroptic mange in both ear canals. The animals were divided into two groups of five: control, without treatment (GI) and a second group (GII) treated with a single application of 2% permethrin. The diagnosis was realized by collecting fragments of crusts from both ear canals and submitting to stereomicroscopy for the presence and evaluation of mites' motility. On day 0 the animals from GII were treated topically with 2mg of 2% permethrin in each ear canal. No other treatment or environmental decontamination was performed during the trial. The rabbits were evaluated daily for observation of possible side effects. To evaluate the efficacy, collections of material were undertaken on days: +7, +14, +21. The formulation containing 2% permethrin was 100% effective in the control of P. ovis in naturally infested rabbits, along all days of observation. No adverse reactions were observed in the treated animals.

[Activity of neem extract on the embryonary development of Ctenocephalides felis felis (Bouché, 1835) (Siphonaptera: Pulicidae)]. / Atividade do extrato de nim sobre o desenvolvimento embrionário de Ctenocephalides felis felis (Bouché, 1835) (Siphonaptera: Pulicidae).

The present study had as objective to evaluate the activity of limonoid azadiractin, extracted of the seeds of the plant Azadirachta indica, neem, on the embryonary development of Ctenocephalides felis felis. A dog was sprayed with the formulation 10%, another dog was kept as control, without treatment. Both had been infested weekly with 600 fleas, in the ratio of 1:1 between males and females. The deriving positions of the infestations had been incubate per seven days in assay pipes, and evaluated it percentage of emerging of flea eggs, comparing themselves the averages of the groups treat and have controlled. The extract of nim presented activity on the embryonary development of C. f. felis, keeping superior levels of effectiveness 80% until day +14, beyond diminishing the position and inhibiting the development between urging larval of the percentage of larvae that had come out.