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Rev Soc Bras Med Trop ; 32(3): 291-4, 1999.
Article in Portuguese | MEDLINE | ID: mdl-10380569

ABSTRACT

A patient with AIDS and asymptomatic Chagas's disease and positive xenodiagnosis was taking ketoconazole in order to suppress parasitemia and prevent reactivation of Chagas's disease. Ketoconazole was unplanned suspended after 6 months, and the patient was admitted with fever, headache, vomiting, tachycardia, postural hypotension, hepatosplenomegaly, and positive xenodiagnosis one month later. Treatment with benzonidazole was begun leading to suppression of parasitemia. The patient had probability a neurotoxoplasmosis associated and progressed to coma and death with sepsis. No parasite was found in autopsy.


Subject(s)
AIDS-Related Opportunistic Infections/drug therapy , Chagas Disease/drug therapy , Animals , Antifungal Agents/therapeutic use , Fatal Outcome , Female , Humans , Ketoconazole/therapeutic use , Middle Aged , Nitroimidazoles/therapeutic use , Recurrence , Trypanocidal Agents/therapeutic use , Trypanosoma cruzi
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