Eating habits, lifestyle and intestinal constipation in children aged four to seven years.

INTRODUCTION: Objective: to investigate the association between intestinal constipation, lifestyle and eating habits in four to seven year old children. Methods: a cross-sectional study with a sample of 152 children aged four to seven years old. Intestinal constipation was characterized according to the Rome IV criteria. Excess weight was classified by the body mass index. Variables that could be associated with constipation, such as maternal constipation, lifestyle, food and water intake, were selected. In the analysis, the prevalence ratio using Poisson regression, with a robust variance and statistical significance was set at p < 0.05. Results: the prevalence of intestinal constipation was 32.2% (n = 49), of which 34.7% (n = 17) of the children were overweight. As for lifestyle, 73% of the children did not practice any regular physical activities and approximately 60% spent more than two hours a day in sedentary activities, such as watching television or playing electronic games. A statistically significant association was found between constipation and daily school time equal to or greater than 4.5 hours (p = 0.007), non-consumption of fruits (p = 0.003) and greens (p = 0.007) and regular intake of fried food (p = 0.003). Conclusion: an association between intestinal constipation and unhealthy habits, such as non-consumption of fruits and vegetables, and regular consumption of fried food was observed. Preventing intestinal constipation requires changes in the lifestyle and eating habits of the children and family.

INTRODUCCIÓN: Objetivo: investigar la asociación entre estreñimiento intestinal, estilo de vida y hábitos alimentarios en niños de cuatro a siete años. Métodos: estudio transversal con muestra de 152 niños de cuatro a siete años. El estreñimiento intestinal se caracterizó según los criterios de Roma IV. El exceso de peso fue clasificado por el índice de masa corporal. Se seleccionaron variables que podrían estar asociadas al estreñimiento, como el estreñimiento materno, el estilo de vida, los hábitos alimentarios y el consumo de agua. En los análisis, la razón de prevalencia mediante regresión de Poisson con una varianza robusta y significación estadística se estableció < 0,05. Resultados: la prevalencia de estreñimiento intestinal fue del 32,2%, de la cual el 34,7% presentaba un exceso de peso. En cuanto al estilo de vida, el 71% de los niños no practicaba actividad física regular y aproximadamente el 60% pasaba más de dos horas diarias realizando actividades sedentarias, como ver la televisión y jugar a videojuegos. Se pudo constatar una asociación estadísticamente significativa entre el estreñimiento y un tiempo diario en la escuela igual o superior a 4,5 horas (p = 0,007), escaso consumo de frutas (p = 0,003) y verduras (p = 0,007) y consumo regular de frituras (p = 0,003). Conclusiones: se pudo observar una relación directa entre el estreñimiento intestinal y los hábitos no saludables, como no consumir frutas y verduras y el consumo regular de frituras. La prevención del estreñimiento intestinal requiere cambios en el estilo de vida y los hábitos alimentarios del niño y la familia.

Eating habits, lifestyle and intestinal constipation in children aged four to seven years / Hábitos alimentarios, estilo de vida y estreñimiento intestinal en niños de cuatro a siete años

Objective: to investigate the association between intestinal constipation, lifestyle and eating habits in four to seven year old children. Methods: a cross-sectional study with a sample of 152 children aged four to seven years old. Intestinal constipation was characterized according to the Rome IV criteria. Excess weight was classifi ed by the body mass index. Variables that could be associated with constipation, such as maternal constipation, lifestyle, food and water intake, were selected. In the analysis, the prevalence ratio using Poisson regression, with a robust variance and statistical signifi cance was set at p < 0.05. Results: the prevalence of intestinal constipation was 32.2% (n = 49), of which 34.7% (n = 17) of the children were overweight. As for lifestyle, 73% of the children did not practice any regular physical activities and approximately 60% spent more than two hours a day in sedentary activities, such as watching television or playing electronic games. A statistically significant association was found between constipation and daily school time equal to or greater than 4.5 hours (p = 0.007), non-consumption of fruits (p = 0.003) and greens (p = 0.007) and regular intake of fried food (p = 0.003). Conclusion: an association between intestinal constipation and unhealthy habits, such as non-consumption of fruits and vegetables, and regular consumption of fried food was observed. Preventing intestinal constipation requires changes in the lifestyle and eating habits of the children and family

Objetivo: investigar la asociación entre estreñimiento intestinal, estilo de vida y hábitos alimentarios en niños de cuatro a siete años. Métodos: estudio transversal con muestra de 152 niños de cuatro a siete años. El estreñimiento intestinal se caracterizó según los criterios de Roma IV. El exceso de peso fue clasificado por el índice de masa corporal. Se seleccionaron variables que podrían estar asociadas al estreñimiento, como el estreñimiento materno, el estilo de vida, los hábitos alimentarios y el consumo de agua. En los análisis, la razón de prevalencia mediante regresión de Poisson con una varianza robusta y significación estadística se estableció < 0,05. Resultados: la prevalencia de estreñimiento intestinal fue del 32,2%, de la cual el 34,7% presentaba un exceso de peso. En cuanto al estilo de vida, el 71% de los niños no practicaba actividad física regular y aproximadamente el 60% pasaba más de dos horas diarias realizando actividades sedentarias, como ver la televisión y jugar a videojuegos. Se pudo constatar una asociación estadísticamente significativa entre el estreñimiento y un tiempo diario en la escuela igual o superior a 4,5 horas (p = 0,007), escaso consumo de frutas (p = 0,003) y verduras (p =0,007) y consumo regular de frituras (p = 0,003). Conclusiones: se pudo observar una relación directa entre el estreñimiento intestinal y los hábitos no saludables, como no consumir frutas y verduras y el consumo regular de frituras. La prevención del estreñimiento intestinal requiere cambios en el estilo de vida y los hábitos alimentarios del niño y la familia

Markers of healthy eating habits, water intake, and constipation in children between 4 and 7 years of age / Marcadores de alimentação saudável, ingestão de água e constipação intestinal em crianças de 4 a 7 anos de idade

ABSTRACT Objective To evaluate the association between diet and constipation in children between four and seven years of age. Methods A cross-sectional study with 152 children between 4 and 7 years of age residing in Viçosa, Brazil. Constipation was defined in accordance with the Rome IV diagnostic criteria. Dietary habits were evaluated based on the frequency of food intake using a food diary for three days. Dietary analysis considered foods deemed healthy and unhealthy which could be associated with constipation, as well as the children's consumption of fruits and vegetables. The amounts of fiber and water consumed were also rated as adequate or inadequate. As part of the analyses, Student's t-test and the chi-square test were performed with a significance level of p<0.05. Results The prevalence of constipation was 32.2%. Constipation was more common among children who did not consume fruits (p=0.020) or greens (p=0.002), as well as among children who consumed "instant" chocolate drinks (p=0.033). An association was found between the frequent consumption of fried food (p=0.020), a daily water intake lower than 600mL, and constipation (p=0.028). Conclusion Unhealthy eating habits among children, such as the lack of fruit and greens intake and the consumption of "instant" chocolate drinks and fried foods, were found to be positively correlated with constipation. The low fruit and vegetable consumption observed herein reflects the need for changes in children's eating habits and the implementation of measures to promote the intake of healthy foods.

RESUMO Objetivo O estudo visa avaliar a associação do consumo alimentar de crianças de quatro a sete anos de idade com constipação intestinal. Métodos Foi realizado estudo transversal com 152 crianças de 4 a 7 anos, residentes em Viçosa, Minas Gerais, Brasil. A constipação intestinal foi identificada de acordo com os critérios de Roma IV. Avaliou-se o consumo alimentar por meio da frequência de consumo de alimentos e do registro alimentar de três dias. Na análise do consumo alimentar selecionaram-se os alimentos marcadores de alimentação saudável e não saudável que poderiam estar associados à constipação, além do consumo agrupado de frutas, verduras e legumes. Verificou-se ainda adequação do consumo de fibras e ingestão de água. Nas análises, foram realizados os testes t-Student e qui-quadrado, considerando-se como significância estatística p<0,05. Resultados A prevalência de constipação foi de 32,2%, sendo maior entre as crianças que não consumiam frutas (p=0,020) e verduras (p=0,002) e consumiam achocolatados (p=0,033). Houve associação entre a constipação (p=0,028) e o consumo frequente de frituras (p=0,020), ingestão diária de água inferior a 600mL. Conclusão Hábitos não saudáveis das crianças, como a baixa ingestão de frutas e verduras, e o consumo de achocolatado e frituras, contribuíram para a associação positiva com a constipação. O baixo consumo de frutas, verduras e legumes revela a necessidade de alteração dos hábitos alimentares das crianças, bem como da implantação de ações para incentivo ao consumo de alimentos saudáveis.

Clinical-nutritional, inflammatory and oxidative stress predictors in hemodialysis mortality: a review.

The evaluation of clinical-nutrition status is essential to increase life quality and improve clinical outcomes of patients in hemodialysis (HD). In the absence of a gold standard, the goal of this integrative review was to present and discuss the latest scientific literature on the ability of clinical-nutritional indicators and inflammatory and oxidative stress markers to predict morbidity and mortality in HD. In this context, the lean and fat mass indexes have become good predictors of mortality in HD individuals, regardless of BMI. Subjective scoring systems have been more sensitive to malnutrition, and altogether anthropometric indicators may result in an early detection of mortality risk in this population. On the other hand, inflammation in HD, as assessed by C-reactive protein, is not only related to cardiometabolic alterations, but it is also one of the key-points in the development of malnutrition, exacerbated by the state of oxidative stress, which has been identified in this group by the increase of the serum levels of gamma-glutamyl transferase and malondialdehyde.

Anti-obesity effects of tea from Mangifera indica L. leaves of the Ubá variety in high-fat diet-induced obese rats.

Due to the high content of bioactive compounds, herbal teas are being investigated as adjuvant in chronic disease management. Studies have shown that mango leaf tea contain mangiferin, total phenolics and antioxidants, compounds with many functional properties. Therefore, this study aims to evaluate the anti-obesity effects of tea from Mangifera indica L. leaves, Ubá variety (TML), in obese rats fed a high-fat diet (HFD). For this, adult male Wistar rats were divided into three groups (n=8): the control group (fed AIN-93 diet), obese group (fed a HFD) and treated group (fed a HFD and supplemented with TML for 8 weeks). We analysed biometric measures and serum biochemical parameters of metabolic control, inflammation and oxidative stress biomarkers, histomorphometry of visceral adipose tissue and mRNA expression of peroxisome proliferator-activated receptor gamma co-activator 1 alpha (PPAR-γ), lipoprotein lipase (LPL) and fatty acid synthase (FAS). The consumption of TML (24.7±2.1mL/day) exerted antioxidant and anti-inflammatory effects, increasing total antioxidant capacity and interleukin-10 serum concentrations, reduced abdominal fat accumulation, upregulated PPAR-γ and LPL and downregulated FAS expression. Our data suggest that TML has therapeutic potential in treating obesity and related diseases through regulating the expression of transcriptional factors and enzymes associated with adipogenesis.

Nutritional status variation and intestinal and extra intestinal symptomatology in patients with celiac disease and non-celiac gluten sensitivity given specialized dietary advice / Evolução do estado nutricional e sintomatologia intestinal e extra intestinal em pacientes com doença celíaca e sensibilidade ao glúten não celíaca submetidos à orientação dietética especializada

ABSTRACT Objective: To investigate the nutritional status variation and symptomatology of patients with celiac disease and non-celiac gluten sensitivity after specialized dietary advice Methods: This prospective study included 80 patients with celiac disease and non-celiac gluten sensitivity. Clinical, metabolic, and nutritional variables were collected from medical records, and the symptomatology was investigated by the Metabolic Screening Questionnaire. The variables were assessed on two occasions (T1 - before dietary advice and T2 - after dietary advice) with an interval of three months between T1 and T2 Results: The median age was 42 years. The prevalences of celiac disease and non-celiac gluten sensitivity were 66.2% and 33.8%, respectively. Normal weight prevailed at T1 (58.8%) and T2 (56.3%), but 30.0% of the patients at T1 and 34.9% of the patients at T2 had excess weight. The two conditions had similar symptomatology. The most frequent signs and symptoms on both occasions involved the gastrointestinal tract, followed by energy/activity and emotions. All symptoms decreased significantly after the introduction of a proper diet Conclusion: The patients were normal weight on both study occasions (T1 and T2), and the symptoms improved after dietary advice. Thus, we reinforce the importance of proper dietary management in both clinical conditions to make dietary adjustments that improve these individuals' symptomatology.

RESUMO Objetivo: Investigar a evolução do estado nutricional e a sintomatologia de pacientes com doença celíaca e sensibilidade ao glúten não celíaca após orientação dietética especializada Métodos: O estudo prospectivo foi realizado com 80 pacientes portadores da doença celíaca e de sensibilidade ao glúten não celíaca. A coleta das variáveis clínicas, metabólicas e nutricionais foi feita por análise dos prontuários, enquanto a sintomatologia foi investigada por meio de Questionário de Rastreamento Metabólico. As variáveis foram avaliadas em dois momentos (T1 - antes da orientação dietética e T2 - após orientação dietética), com intervalo de 3 meses entre T1 e T2 Resultados: A mediana de idade foi de 42 anos. A prevalência de doença celíaca e de sensibilidade ao glúten não celíaca foi de 66,2% e 33,8%, respectivamente. A eutrofia prevaleceu como estado nutricional de T1 (58,8%) e T2 (56,3%), porém 30,0% dos pacientes em T1 e 34,9% em T2 apresentaram excesso de peso. A sintomatologia foi similar entre as duas enfermidades. Os sinais e sintomas mais frequentes nos dois tempos foram os do trato digestório, seguido pelos relacionados à energia/atividade e às emoções. Todos os sintomas diminuíram significativamente após a introdução da dieta Conclusão: Os pacientes apresentaram estado nutricional de eutrofia nos dois momentos avaliados (T1 e T2) e houve redução dos sintomas após as orientações nutricionais. Dessa forma, reitera-se a importância do manejo dietético adequado para ambas as enfermidades clínicas a fim de adequar a dieta que favoreça a melhora da sintomatologia apresentada por esses indivíduos.

Gut microbiota and probiotics: Focus on diabetes mellitus.

The characterization of gut microbiota has become an important area of research in several clinical conditions, including type 2 diabetes (T2DM). Changes in the composition and/or metabolic activity of the gut microbiota can contribute to human health. Thus, this review discusses the effects of probiotics and gut microbiota on metabolic control in these individuals. Relevant studies were obtained from electronic databases such as PubMed/Medline and ISI Web of Science. The main probiotics used in these studies belonged to the genera Lactobacillus and Bifidobacterium. The authors found seven randomized placebo-controlled clinical trials and 13 experimental studies directly related to the effect of probiotics on metabolic control in the context of T2DM. The hypothesis that gut microbiota plays a role in the development of diabetes indicates an important beginning, and the potential of probiotics to prevent and reduce the severity of T2DM is better observed in animal studies. In clinical trials, the use of probiotics in glycemic control presented conflicting results, and only few studies have attempted to evaluate factors that justify metabolic changes, such as markers of oxidative stress, inflammation, and incretins. Thus, further research is needed to assess the effects of probiotics in the metabolism of diabetic individuals, as well as the main mechanisms involved in this complex relationship.

Percepção de agricultores familiares do Programa de Aquisição de Alimentos (PAA) sobre o significado de fazer parte do PAA e a sua compreensão sobre conceitos relacionados à alimentação, nutrição e saúde / The perception of family farmers of Programa de Aquisição de Alimentos (PAA) on the meaning of being part of PAA and their understanding of concepts related to food, nutrition and health

A agricultura familiar possui um reconhecido potencial econômico, ambiental e social que nos últimos anos tem sido prestigiado e fortalecido por programas governamentais que incentivam a produção e o beneficiamento de seus produtos, sendo assim, ações de Segurança Alimentar e Nutricional (SAN) podem ser implementadas, aumentando a disponibilidade de alimentos e a variabilidade de nutrientes à população, favorecendo a comercialização deles em nível local e regional, além de contribuir para hábitos alimentares saudáveis e, consequentemente, melhorar a qualidade da alimentação. O Programa de Aquisição de Alimentos (PAA) foi instituído pelo artigo 19 da Lei nº 10.696 em 2003, como uma das ações do Programa Fome Zero, seu objetivo principal é o fortalecimento da agricultura familiar. O objetivo deste trabalho foi identificar as percepções dos agricultores sobre o significado de fazer parte do PAA e a sua compreensão sobre conceitos relacionados à alimentação, nutrição e saúde, por meio de uma pesquisa qualitativa. Os resultados do estudo foram maior acesso a informações como saúde, alimentação, formas de produção e manejo, economia, direitos e deveres, entre outras; melhora de renda e investimentos familiares; melhora da autoestima/valorização pessoal e estímulo à interação dos agricultores familiares. Nesse contexto, faz-se necessário que o PAA se torne cada vez mais um instrumento fortalecedor da agricultura familiar, das ações de saúde e de SAN e nutricional de forma permanente como proposto em sua lei de criação.

Family agriculture has a recognized economic, environmental and social potential, which in recent years has been prestigious and strengthened by government programs that encourage the production and processing of their products, thus Food and Nutrition Security actions can be implemented, increasing the availability of food and the variability of nutrients to the population, favoring the their marketing at local and regional levels, contributing to healthy eating habits and thus improving the quality of food. The Programa de Aquisição de Alimentos (PAA) [Food Acquisition Program] was established by the article 19 of Law nº 10.696 in 2003 as one of the actions of the Programa Fome Zero [Zero Hungry Program] your main goal is the strengthening of family agriculture. The objective of this study was to identify the perceptions of farmers on the meaning of being part of the PAA and their understanding of concepts related to food, nutrition and health through a qualitative research. The results of this study were greater access to information such as health, food, forms of production and management, economics, rights and duties, among others; improved income and family investments; improved self-esteem/self-worth and stimulate the interaction of family farmers. In this context, it is necessary that the PAA increasingly become an empowering tool of agriculture family in the health care and Food and Nutrition Security permanently as proposed in his law of creation.

Perfil nutricional e fatores associados ao baixopeso e à redução do consumo alimentar emcrianças hospitalizadas / Nutritional profile and factors associaed with low body weight andreduction of food intake in hospitalized children

A avaliação do estado nutricional de crianças hospitalizadas assume um papel fundamental na identificação precocede riscos nutricionais. Assim, é de grande relevância identificar variáveis que exercem impacto no estado nutricional ena aceitação dos alimentos no ambiente hospitalar. O objetivo do trabalho foi avaliar o perfil nutricional de criançasinternadas em um hospital e analisar as variáveis que exercem influência no diagnóstico nutricional e no consumoalimentar durante a hospitalização. O estado nutricional foi avaliado por meio da aferição de peso, comprimento/estatura,cálculo do Índice de Massa Corporal e avaliação dos índices antropométricos. A avaliação bioquímica foi realizadaa partir das informações disponíveis no prontuário clínico. Os dados socioeconômicos, alimentares, de aleitamentomaterno e avaliação da aceitação das refeições oferecidas foram coletados por meio de aplicação de um questionárioao responsável pela criança. Participaram do estudo 208 crianças, sendo 61,5% do sexo masculino e mediana deidade de 21,5(6-59) meses. Quanto ao estado nutricional, 80% das crianças foram classificadas como eutróficas, 10%apresentavam magreza e 10% excesso de peso. As crianças com baixo peso tiveram mais linfocitopenia (p=0,038)e também foram as que apresentaram menor tempo de aleitamento materno exclusivo (p=0,015). As crianças queapresentaram concentrações elevadas de PCR e leucócitos apresentaram baixa aceitação da dieta oferecida (p=0,034e p=0,040, respectivamente). Foram identificados fatores que se associaram ao baixo peso e a menor aceitação dasrefeições pelas crianças. Assim, atenção específica deve ser dada àquelas com alteração do estado inflamatório e commenor tempo de aleitamento materno exclusivo.

The evaluation of nutritional status in hospitalized children plays a critical role in the early identification of nutritionalrisk. Thus, it is of great importance to identify variables that have an impact on nutritional status and acceptance of foodin the hospital environment. The objective of this work to evaluate the nutritional status of hospitalized children, thevariables that influence the nutritional diagnosis and food intake during hospitalization. Nutritional status was evaluatedby measurement of weight, length / height, body mass index and anthropometric indices. The biochemical evaluationwas performed based on the information available in the medical record. Socioeconomic, dietary and breastfeedingdata and, evaluation of the acceptance of meals offered were obtained through a questionnaire to the responsable forthe children. The study included 208 children, predominantly male (61.5%) and median age of 21.5 (6-59) months. Inrelation to nutritional status, 80% of children were classified eutrophic, 10% were thinness and 10% overweight. Childrenwith low weight had more cases of lymphocytopenia (p = 0.038) and were also those who had shorter time of exclusivebreastfeeding (p = 0.015). Children with elevated concentrations of PCR and leukocytes showed low acceptance of theoffered diet (p = 0.034 and p = 0.040, respectively). Factors associated with low weight and lower acceptance of mealsby children were identified. Particular attention should be given to children with altered inflammatory status and shortertime of exclusive breastfeeding.

Avaliação da estabilidade da capacidade antioxidante e de parâmetros físico-químicos de néctares de frutas caseiros / Assessment of the antioxidant capacity and of the physicalchemicals parameters stability in homemade fruit nectars

Este estudo avaliou a capacidade antioxidante e os indicadores físico-químicos de néctares caseiros de laranja, manga e maracujá, mantidos sob refrigeração (5 ± 2 o C) por 24 horas. Os néctares foram preparados em laboratório e mantidos sob refrigeração, simulando as condições domésticas. As análises foram realizadas após o preparo (T0) e durante o acondicionamento sob refrigeração (1 h, 4 h e 24 h). Os sólidos solúveis, pH e cor foram determinados respectivamente por refratometria, potenciometria e colorimetria. Carotenoides e ácido ascórbico foram analisados por cromatografia líquida de alta eficiência; a concentração de compostos fenólicos foi determinada utilizando-se o reagente de Folin Ciocalteau e a atividade antioxidante pelo teste do DPPH. Ácido ascórbico, β-caroteno e compostos fenólicos foram identificados em todos os néctares. Foram encontrados α-caroteno e β-criptoxantina no néctar de laranja e licopeno no néctar de manga. Durante 24 horas de refrigeração, os compostos analisados e a atividade antioxidante mantiveram-se estáveis. De forma geral, os parâmetros físico-químicos também se mantiveram estáveis durante o período avaliado. Em conclusão, sob as condições utilizadas no presente estudo, os néctares não apresentaram alteração da capacidade antioxidante, podendo ser considerados fontes de carotenoides e vitamina C, mesmo se consumidos após 24 horas de preparo.

The objective of the study was to evaluate the antioxidant capacity and the physical-chemical indicators of homemade nectars of orange, mango and passion fruit, kept under refrigeration (5 ± 2 °C) for 24 hours. The nectars were prepared in laboratory and kept under refrigeration simulating the domestic conditions. The samples analyses were performed after their preparations (T0) and during the refrigerated storage (1 h, 4 h and 24 h). Soluble solids, pH and color were determined by refractometry, colorimetry and potentiometry, respectively. Carotenoids and ascorbic acid were analyzed by high performance liquid chromatography, the concentration of phenolic compounds were determined by using Folin Ciocalteau reagent, and the antioxidant activity by the DPPH test. Ascorbic acid, β-carotene and phenolic compounds were identified in all of the analyzed nectars samples. The α-carotene and β-cryptoxanthin were found in orange nectar and the lycopene in mango nectar samples. During the refrigeration for 24 hours, the analyzed compounds and the antioxidant activity remained stable. In general, the physical-chemicals parameters also remained stable during the storage for 24 hours. In conclusion, under the conditions used in this study, the nectars might be considered as antioxidant sources, even if consumed after being prepared 24 hours before.

Avaliação da estabilidade da capacidade antioxidante e de parâmetros físico-químicos de néctares de frutas caseiros / Assessment of the antioxidant capacity and of the physicalchemicalsparameters stability in homemade fruit nectars

Este estudo avaliou a capacidade antioxidante e os indicadores físico-químicos de néctares caseirosde laranja, manga e maracujá, mantidos sob refrigeração (5 ± 2 oC) por 24 horas. Os néctaresforam preparados em laboratório e mantidos sob refrigeração, simulando as condições domésticas.As análises foram realizadas após o preparo (T0) e durante o acondicionamento sob refrigeração(1 h, 4 h e 24 h). Os sólidos solúveis, pH e cor foram determinados respectivamente por refratometria,potenciometria e colorimetria. Carotenoides e ácido ascórbico foram analisados por cromatografialíquida de alta eficiência; a concentração de compostos fenólicos foi determinada utilizando-seo reagente de Folin Ciocalteau e a atividade antioxidante pelo teste do DPPH. Ácido ascórbico,β-caroteno e compostos fenólicos foram identificados em todos os néctares. Foram encontradosα-caroteno e β-criptoxantina no néctar de laranja e licopeno no néctar de manga. Durante 24 horasde refrigeração, os compostos analisados e a atividade antioxidante mantiveram-se estáveis. De formageral, os parâmetros físico-químicos também se mantiveram estáveis durante o período avaliado.Em conclusão, sob as condições utilizadas no presente estudo, os néctares não apresentaramalteração da capacidade antioxidante, podendo ser considerados fontes de carotenoides e vitamina C,mesmo se consumidos após 24 horas de preparo.

The objective of the study was to evaluate the antioxidant capacity and the physical-chemicalindicators of homemade nectars of orange, mango and passion fruit, kept under refrigeration(5 ± 2 °C) for 24 hours. The nectars were prepared in laboratory and kept under refrigerationsimulating the domestic conditions. The samples analyses were performed after their preparations(T0) and during the refrigerated storage (1 h, 4 h and 24 h). Soluble solids, pH and color weredetermined by refractometry, colorimetry and potentiometry, respectively. Carotenoids andascorbic acid were analyzed by high performance liquid chromatography, the concentrationof phenolic compounds were determined by using Folin Ciocalteau reagent, and the antioxidantactivity by the DPPH test. Ascorbic acid, β-carotene and phenolic compounds were identified inall of the analyzed nectars samples. The α-carotene and β-cryptoxanthin were found in orangenectar and the lycopene in mango nectar samples. During the refrigeration for 24 hours,the analyzed compounds and the antioxidant activity remained stable. In general, thephysical-chemicals parameters also remained stable during the storage for 24 hours. In conclusion,under the conditions used in this study, the nectars might be considered as antioxidant sources,even if consumed after being prepared 24 hours before.

Measurements of body fat distribution: assessment of collinearity with body mass, adiposity and height in female adolescents / Medidas de localização da gordura corporal: uma avaliação da colinearidade com massa corporal, adiposidade e estatura em adolescentes do sexo feminino

OBJECTIVE : To verify the correlation between body fat location measurements with the body mass index (BMI), body fat percentage (BF%) and height, according to the nutritional status in female adolescents. METHODS : A controlled cross-sectional study was carried out with 113 adolescents (G1: 38 with normal weight, but with high body fat level, G2: 40 with normal weight and G3: 35 overweight) from public schools in Viçosa-MG, Brazil. The following measures were assessed: weight, height, waist circumference (WC), umbilical circumference (UC), hip circumference (HC), thigh circumference, waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), waist-to-thigh ratio (WTR), conicity index (CI), sagittal abdominal diameter (SAD), coronal diameter (CD), central (CS) and peripheral skinfolds (PS). The BF% was assessed by tetrapolar electric bioimpedance. RESULTS : The increase in central fat, represented by WC, UC, WHtR, SAD, CD and CS, and the increase in peripheral fat indicated by HC and thigh circumference were proportional to the increase in BMI and BF%. WC and especially the UC showed the strongest correlations with adiposity. Weak correlation between WHR, WTR, CI and CS/PS with adiposity were observed. The height showed correlation with almost all the fat location measures, being fair or weak with waist measurements. CONCLUSIONS : The results indicate colinearity between body mass and total adiposity with central and peripheral adipose tissue. We recommend the use of UC for assessing nutritional status of adolescents, as it showed the highest capacity to predict adiposity in each group, and also showed fair or weak correlation with height. .

OBJETIVO: Verificar a correlação entre medidas de localização da gordura corporal com índice de massa corporal (IMC), percentual de gordura corporal (%GC) e estatura, de acordo com o estado nutricional em adolescentes do sexo feminino. MÉTODOS: Realizou-se estudo transversal controlado, com 113 adolescentes (G1: 38 eutróficas mas com gordura corporal elevada; G2: 40 eutróficas e G3: 35 com excesso de peso), de 14 a 19 anos, de escolas públicas de Viçosa-MG. Aferiu-se peso, estatura, circunferência da cintura (CC), circunferência umbilical (CUm), circunferência do quadril (CQ), circunferência da coxa, relação cintura/quadril (RCQ), relação cintura/estatura (RCE), relação cintura/coxa (RCC), índice de conicidade (IC), diâmetro abdominal sagital (DAS), diâmetro coronal (DC), pregas cutâneas centrais (PCC) e periféricas (PCP). Avaliou-se o %GC por bioimpedância elétrica tetrapolar. RESULTADOS: O aumento da gordura central, representada pela CC, CUm, RCE, DAS, DC e PCC, e o aumento da gordura periférica indicado pela CQ e da coxa foram proporcionais ao aumento do IMC e %GC. A CC e principalmente CUm apresentaram as correlações mais fortes com a adiposidade, enquanto RCQ, RCC, IC e PCC/PCP as mais fracas. A estatura apresentou correlação com praticamente todas as medidas de localização de gordura, sendo de fraca a regular com as medidas da cintura. CONCLUSÕES: Os resultados indicam colinearidade entre massa corporal e adiposidade total com tecido adiposo central e periférico. Recomenda-se o emprego da CUm na avaliação do estado nutricional de adolescentes, pois ela apresentou maior capacidade para predizer adiposidade em cada grupo, além de correlação fraca a regular com a estatura. .

[Measurements of location of body fat distribution: an assessment of colinearity with body mass, adiposity and stature in female adolescents]. / Medidas de localização da gordura corporal: uma avaliação da colinearidade com massa corporal, adiposidade e estatura em adolescentes do sexo feminino.

OBJECTIVE: To verify the correlation between body fat location measurements with the body mass index (BMI), percentage of body fat (%BF) and stature, according to the nutritional status in female adolescents. METHODS: A controlled cross sectional study was carried out with 113 adolescents (G1: 38 eutrophic, but with high body fat level, G2: 40 eutrophic and G3: 35 overweight) from public schools in Viçosa-MG, Brazil. The following measures have been assessed: weight, stature, waist circumference (WC), umbilical circumference (UC), hip circumference (HC), thigh circumference, waist-to-hip ratio (WHR), waist-to-stature ratio (WSR), waist-to-thigh ratio (WTR), conicity index (CI), sagittal abdominal diameter (SAD), coronal diameter (CD), central skinfolds (CS) and peripheral (PS). The %BF was assessed by tetrapolar electric bioimpedance. RESULTS: The increase of central fat, represented by WC, UC, WSR, SAD, CD and CS, and the increase of peripheral fat indicated by HC and thigh were proportional to the increase of BMI and %BF. WC and especially the UC showed the strongest correlations with adiposity. Weak correlation between WHR, WTR, CI and CS/PS with adiposity were observed. The stature showed correlation with almost all the fat location measures, being regular or weak with waist. CONCLUSIONS: The results indicate colinearity between body mass and total adiposity with central and peripheral adipose tissue. We recommend the use of UC for assessing nutritional status of adolescents, because it showed the highest ability to predict adiposity in each group, and also presented regular or weak correlation with stature.

Perfil sociossanitário de portadores de hipertensão arterial cadastrados na estratégia saúde da família, Divinésia, Minas Gerais / Health and social profile of hypertensive patients enrolled in the family health strategy, Divinésia, Minas Gerais

A Hipertensão Arterial (HA) é um problema grave de saú- de pública no Brasil e no mundo, sendo a mais frequente das doenças cardiovasculares. As modificações no estilo de vida são consideradas fundamentais para prevenção e controle da HA. Destarte, este estudo tem como objetivo descrever o perfil sociossanitário de portadores de HA cadastrados na Estratégia de Saúde da Família (ESF) de Divinésia. Trata-se de um estudo descritivo realizado com 61 portadores de HA cadastrados na ESF. Observou-se predominância do sexo feminino, 73,80%; e de idosos, 54,10%. A média de IMC do grupo foi 28,30+4,19 kg/m2 . Mais de 80% dos indivíduos eram aposentados e, em rela- ção à prática de exercícios físicos, 59,02% não realizavam e 37,70% faziam caminhada. Quanto ao conhecimento da doença, 78,69% afirmaram não saber informar o que é a HA, 21,31% responderam mesmo que com algum grau de imprecisão. Cerca de 70% dos entrevistados mostrou habilidade para identificar algum tipo de tratamento para a HA. Observou-se que grande parte destes desconhecia aspectos importantes de sua morbidade. Os resultados mostram a importância de se introduzir práticas educativas no âmbito da ESF que promovam o empoderamento desses indivíduos.

Arterial Hypertension (AH) is a serious public health problem in Brazil and worldwide, being the most common cardiovascular disease. Changes in lifestyle are considered essential to prevent and control AH. Thus, this study aims to describe the health and social profile of AH patients registered at the Family Health Strategy (FHS) in Divinésia, MG. It is a descriptive study conducted with 61 AH patients enrolled in the FHS. There was a predominance of females, 73.80%; and of the elderly, 54.10%. The mean BMI was 28.30+4.19 kg/m2 . More than 80% were retired and, in relation to physical activity, 59.02% did no activity and 37.70% did walking. Regarding their knowledge about the disease, 78.69% were not able to answer "what is hypertension?", only 21.31% answered the question, though with some inaccuracy. Roughly 70% of the respondents displayed an ability to identify some type of treatment for AH. It was observed that most of them were unaware of important aspects of their morbidity. The results show the importance of introducing educational practices in the FHS context that promote the empowerment of these individuals.

Low energy and carbohydrate intake associated with higher total antioxidant capacity in apparently healthy adults.

OBJECTIVES: The aim of this study was to investigate the associations between plasma total antioxidant capacity (TAC) and anthropometric, biochemical, clinical, and dietary measurements in young and apparently healthy individuals. METHODS: We evaluated 156 individuals (91 women and 65 men; ages 23.1 ± 3.5 y; body mass index 22 ± 2.9 kg/m(2)) for anthropometrics, biochemical markers, clinical, dietary, and some components of the antioxidant defense system, including the plasma TAC. Statistical analyses were performed to detect differences between individuals with TAC higher and lower than the mean value and to screen the associations between TAC and variables of interest. A linear regression model was fitted to identify TAC predictors. RESULTS: Daily caloric intake and macronutrient consumption were lower in individuals who exhibited the highest TAC values (P < 0.05). Linear regression analysis showed that daily calories and carbohydrate intake was a possible negative TAC predictor (P < 0.05). Nevertheless, there was no difference in the values of oxidized low-density lipoprotein in the individuals separated by means of TAC. In contrast, individuals whose plasma TAC values were above the mean showed higher low-density lipoprotein cholesterol concentrations, total cholesterol/high-density lipoprotein cholesterol values, and selenium in nails (P < 0.05). CONCLUSIONS: In physiological conditions, the caloric intake level seems to be an important factor to act in the modulation of plasma TAC, before establishing anthropometric impairments of body or metabolic composition, or both. Additionally, the plasma TAC increase may be able to act as a compensatory mechanism.

[Insulin resistance and components of metabolic syndrome, analysis by gender and stage of adolescence]. / Resistência à insulina e componentes da síndrome metabólica, análise por sexo e por fase da adolescência.

OBJECTIVE: To analyze the influence of metabolic syndrome components in insulin resistance, by gender and adolescence phase. SUBJECTS AND METHODS: We evaluated biochemical, clinical, lifestyle and body composition data of 800 adolescents from 10 to 19 years old, from both genders, from Viçosa, MG/Brasil, and there was the division by stage: early (10 to 13 years), intermediate (14 to 16 years) and late (17 to 19 years). RESULTS: 10.3 and 3.4% had, respectively, insulin resistance and metabolic syndrome. In the initial phase there was a higher prevalence of dyslipidemia and intermediate hyperuricemia and excess body fat. Females had a higher prevalence of dyslipidemia, excess body fat and insulin resistance and higher male prevalence of low HDL, hyperuricemia and blood pressure changes. Those from the initial phase had higher levels of total cholesterol, LDL, HDL, triglycerides, fasting glucose and waist/hip ratio, stayed less time sitting and had more meals (p < 0.05) in relation to other phases. The final model, adjusted for gender, was different for each phase of adolescence. CONCLUSIONS: Insulin resistance is associated with inadequate body composition, in biochemical levels and lifestyle, being the factors associated different in each phase of adolescence.

Fortificação de massas de pizza com farinha integral de soja do novo cultivar 'UFVTN 105AP' / Fortification of pizza dough's with whole soybean flour of new cultivar 'UFVTN 105AP'

Objetivou-se caracterizar as propriedades físico-químicas e a correlação entre a textura instrumental e a aceitação sensorial de massas de pizza fortificadas com farinha integral de soja. Foram desenvolvidas formulações contendo 0%, 30%, 50% e 70% de farinha integral de soja. A análise de textura indicou que a adição de 50% de soja elevou (P<0,05) a dureza, gomosidade, elasticidade e mastigabilidade da massa de pizza. Os teores de proteína, fibra alimentar e dos minerais cálcio, zinco, magnésio, potássio, cobre e fósforo foram maiores (P<0,05) com o aumento da concentração da farinha de soja. O conteúdo de lipídio foi maior (P<0,05) na massa de pizza com 70% de farinha integral de soja. A formulação controle e aquela contendo 30% de farinha integral de soja foram as mais aceitas, sendo positivamente correlacionadas com a textura instrumental, uma vez que apresentaram menor dureza, gomosidade, elasticidade e mastigabilidade. Portanto, a farinha de soja adicionou minerais antioxidantes, proteína, fibra dietética, ácidos graxos essenciais (ω-6 e ω-3) e manteve a aceitação das massas de pizza, possibilitando o preparo de um alimento com alegação de saúde e qualidade sensorial.

This study aimed to characterize the physicochemical properties and the correlation between the instrumental texture and the sensory acceptance of pizza dough's fortified with whole soybean flour. Formulations were developed to contain 0%, 30%, 50% and 70% whole soybean flour. The texture analysis indicated that the addition of 50% soybean increased (P<0.05) firmness, gumminess, springiness and chewiness of pizza dough. The contents of protein, dietary fiber and and minerals calcium zinc, magnesium, potassium, copper and phosphorus were higher (P<0.05) with increasing concentration of soybean flour. The content of lipid was higher (P<0.05) in the pizza dough with 70% whole soybean flour. The control formulation and that containing 30% whole soybean flour were the most accepted, being positively correlated with the instrumental texture, since it had a lower firmness, gumminess, springiness and chewiness. Thus, the whole soybean flour added antioxidant minerals, protein, dietary fiber, essential fatty acids (ω-6 and ω-3) and maintained the acceptance of the pizza dough's, allowing to prepare food with health claim and sensory quality.

Resistência à insulina e componentes da síndrome metabólica, análise por sexo e por fase da adolescência / Insulin resistance and components of metabolic syndrome, analysis by gender and stage of adolescence

Objetivo: Analisar a influência dos componentes da síndrome metabólica na resistência à insulina, por sexo e fase da adolescência. Sujeitos e métodos: Avaliaram-se dados bioquímicos, clínico, de estilo de vida e composição corporal de 800 adolescentes de 10 a 19 anos, de ambos os sexos, de Viçosa-MG/Brasil, divididos em fases: inicial (10 a 13 anos), intermediária (14 a 16 anos) e final (17 a 19 anos). Resultados: 10,3 e 3,4% apresentavam, respectivamente, resistência à insulina e síndrome metabólica. Na fase inicial, observaram-se maior prevalência de dislipidemia e na intermediária, de hiperuricemia e excesso de gordura corporal. O sexo feminino apresentou maior prevalência de dislipidemia, excesso de gordura corporal e resistência à insulina e o masculino, maior prevalência de HDL baixo, hiperuricemia e pressão arterial alterada. Os da fase inicial apresentaram maiores valores de colesterol total, LDL, HDL, triglicerídeos, glicemia de jejum e relação cintura/quadril, ficaram menos tempo sentados e realizavam maior número de refeições (p < 0,05) em relação às outras fases. O modelo final, ajustado por sexo, foi diferente para cada fase da adolescência. Conclusões: A resistência à insulina está associada à inadequação na composição corporal, nos níveis bioquímicos e no estilo de vida, sendo os fatores associados diferentes em cada fase da adolescência. Arq Bras Endocrinol Metab. 2014;58(6):610-8 .

Objective: To analyze the influence of metabolic syndrome components in insulin resistance, by gender and adolescence phase. Subjects and methods: We evaluated biochemical, clinical, lifestyle and body composition data of 800 adolescents from 10 to 19 years old, from both genders, from Viçosa, MG/Brasil, and there was the division by stage: early (10 to 13 years), intermediate (14 to 16 years) and late (17 to 19 years). Results: 10.3 and 3.4% had, respectively, insulin resistance and metabolic syndrome. In the initial phase there was a higher prevalence of dyslipidemia and intermediate hyperuricemia and excess body fat. Females had a higher prevalence of dyslipidemia, excess body fat and insulin resistance and higher male prevalence of low HDL, hyperuricemia and blood pressure changes. Those from the initial phase had higher levels of total cholesterol, LDL, HDL, triglycerides, fasting glucose and waist/hip ratio, stayed less time sitting and had more meals (p < 0.05) in relation to other phases. The final model, adjusted for gender, was different for each phase of adolescence. Conclusions: Insulin resistance is associated with inadequate body composition, in biochemical levels and lifestyle, being the factors associated different in each phase of adolescence. Arq Bras Endocrinol Metab. 2014;58(6):610-8 .

Modulators of erythrocyte glutathione peroxidase activity in healthy adults: an observational study.

The aim of this study was to investigate the potential modulators of erythrocyte glutathione peroxidase (GPx) activity in young and apparently healthy individuals. One hundred one individuals (53 women and 48 men) were evaluated for anthropometric measurements, biochemical markers, clinical, dietary, and endogenous and exogenous components of the antioxidant defense system. Statistical analysis was performed to detect differences among subjects by the median of GPx activity. A linear regression model and Spearman correlation coefficients were used to screen the associations between GPx activity and interest variables. Individuals with higher GPx enzymatic activity were older and higher circulating levels of oxidized low-density lipoprotein (ox-LDL) values, but conversely lower nail concentrations of selenium and copper (P < 0.05). The GPx activity was positively correlated to truncal fat percentage values (r = 0.24, P = 0.016), circulating levels of ox-LDL (r = 0.28, P = 0.004), and daily vitamin C intake (r = 0.28, P = 0.007), and negatively correlated to the nail concentration of selenium (r = -0.24, P = 0.026). Interesting, it was noticed that the truncal fat percentage and circulating levels of ox-LDL explained 5.9 and 7.4% of the GPx enzymatic activity. Thus, preventive measures such as adequate antioxidant intake and proper fat percentage would be a priority in the nutritional care of young and apparently healthy individuals.

Meal replacement based on Human Ration modulates metabolic risk factors during body weight loss: a randomized controlled trial.

PURPOSE: A meal replacement may be an effective strategy in the management of obesity to increase antioxidant intake, attenuating oxidative stress and inflammation. In the present study, we investigated the efficacy of a new nutritional supplement to reduce metabolic risk parameters in obese women. METHODS: In a randomized controlled crossover study (2 × 2), 22 women (percentage body fat 40.52 ± 3.75%; body mass index-BMI 28.72 ± 2.87 kg/m²; 35.04 ± 5.6 years old) were allocated into two treatments: hypocaloric diet and drink containing "Human Ration" (HR) consumption (CRHR), and hypocaloric diet and control drink consumption (CR). The study consisted of 2 periods of 5 weeks with 1 week of washout in two orders (CR → CRHR and CRHR → CR). Caloric restriction was 15%, based on estimated energy requirement. Anthropometric, clinical and metabolic risk parameters were assessed at baseline and at the end of each period. RESULTS: Some metabolic risk factors were favorably modulated in both interventions: reduction in body weight (CR -0.74 ± 1.27 kg; p = 0.01; CRHR -0.77 ± 1.3 kg; p = 0.02), body mass index (BMI) (CR -0.27 ± 0.51 kg/m²; p = 0.02; CRHR -0.30 ± 0.52 kg/m²; p = 0.01) and HOMA-IR (CR -0.35 ± 0.82; p = 0.02, CRHR -0.41 ± 0.83; p = 0.03). However, CRHR reduced waist circumference (-2.54 ± 2.74 cm; p < 0.01) and gynoid fat (-0.264 ± 0.28 g; p < 0.01), and increased HDL-c levels (0.08 ± 0.15 mmol/l; p = 0.04). CONCLUSION: Associated with hypocaloric diet, the intake of a nutritional supplement rich in phytochemicals as a breakfast substitute for 5 weeks had no additional effect on weight reduction than caloric restriction alone, but increased central lipolysis and improved the lipoprotein profile.